Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Upal Bose"'
Autor:
Hyo-Jin Park, Mi-Jung Kim, Christina Rothenberger, Ashok Kumar, Edith M. Sampson, Dalian Ding, Chul Han, Karessa White, Kevin Boyd, Senthilvelan Manohar, Yong-Hwan Kim, Maria S. Ticsa, Aaron S. Gomez, Isabela Caicedo, Upal Bose, Paul J. Linser, Takuya Miyakawa, Masaru Tanokura, Thomas C. Foster, Richard Salvi, Shinichi Someya
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
A common complication of cisplatin-based chemotherapy is hearing loss. Here, Park et al. show that glutathione transferase α4 (GSTA4) contributes to reducing cisplatin toxicity in the inner ear of female mice by removing 4-hydroxynonenal (4-HNE).
Externí odkaz:
https://doaj.org/article/a4b9d8b940ff4c42bbb2c14bdd319a1a
Autor:
Mi-Jung Kim, Peter B Carmichael, Upal Bose, Yohei Honkura, Jun Suzuki, Dalian Ding, Samantha L Erfe, Shion S Simms, Kishan A Avaiya, Marcus N Milani, Elizabeth J Rymer, Daniella T Fragnito, Nathan Strom, Richard Salvi, Shinichi Someya
Publikováno v:
Hearing Research. 428:108684
Hearing loss is the third most prevalent chronic health condition affecting older adults and age-related hearing loss (ARHL) is the most common form of hearing impairment. Significant sex differences in hearing have been documented in humans and rode
Autor:
Aaron S. Gomez, Yong Hwan Kim, Thomas C. Foster, Mi-Jung Kim, Christina Rothenberger, Upal Bose, Richard Salvi, Isabela Caicedo, Karessa White, Senthilvelan Manohar, Hyo-Jin Park, Dalian Ding, Masaru Tanokura, Edith M. Sampson, Maria S. Ticsa, Paul J. Linser, Ashok V. Kumar, Shinichi Someya, Takuya Miyakawa, Chul Han, Kevin Boyd
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Cisplatin is one of the most widely used chemotherapeutic drugs for the treatment of cancer. Unfortunately, one of its major side effects is permanent hearing loss. Here, we show that glutathione transferase α4 (GSTA4), a member of the Phase II deto
Autor:
Peter Carmichael, Dalian Ding, Masaru Tanokura, Chul Han, Upal Bose, Richard Salvi, Karessa White, Mi-Jung Kim, Shinichi Someya, Kevin Boyd, Christina Rothenberger, Hyo-Jin Park, Paul J. Linser
Publikováno v:
Exp Gerontol
Thioredoxin 2 (TXN2) is a small redox protein found in nearly all organisms. As a mitochondrial member of the thioredoxin antioxidant defense system, TXN2 interacts with peroxiredoxin 3 (PRDX3) to remove hydrogen peroxide. Accordingly, TXN2 is though
Publikováno v:
Pain & Central Nervous System Week; 3/3/2023, p272-272, 1p
Autor:
Park, Hyo-Jin, Kim, Mi-Jung, Rothenberger, Christina, Kumar, Ashok, Sampson, Edith M., Ding, Dalian, Han, Chul, White, Karessa, Boyd, Kevin, Manohar, Senthilvelan, Kim, Yong-Hwan, Ticsa, Maria S., Gomez, Aaron S., Caicedo, Isabela, Bose, Upal, Linser, Paul J., Miyakawa, Takuya, Tanokura, Masaru, Foster, Thomas C., Salvi, Richard
Publikováno v:
Nature Communications; 9/12/2019, Vol. 10 Issue 1, pN.PAG-N.PAG, 1p