Výsledky vyhledávání - "Uosis-Martin M"

C-H functionalization of sp3 centers with Aluminum:A computational and mechanistic study of the baddeley reaction of Decalin

Autor: Lyall, C.L., Sato, M., Uosis-Martin, M., Asghar, S.F., Jones, Matthew, Williams, I.H., Lewis, Simon

Publikováno v: Lyall, C L, Sato, M, Uosis-Martin, M, Asghar, S F, Jones, M, Williams, I H & Lewis, S 2014, ' C-H functionalization of sp 3 centers with Aluminum : A computational and mechanistic study of the baddeley reaction of Decalin ', Journal of the American Chemical Society, vol. 136, no. 39, pp. 13745-13753 . https://doi.org/10.1021/ja5062246

Decalin undergoes reaction with aluminum trichloride and acetyl chloride to form a tricyclic enol ether in good yield, as first reported by Baddeley. This eye-catching transformation, which may be considered to be an aliphatic Friedel-Crafts reaction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1378::6ce4eef63b55bd0f7ad70bc34f9c3177
https://purehost.bath.ac.uk/ws/files/113277594/_JACS_2014_136_13745_.pdf

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Periodical

Rational design, synthesis and testing of novel tricyclic topoisomerase inhibitors for the treatment of bacterial infections part 1Electronic supplementary information (ESI) available. See DOI: 10.1039/d0md00174k

Publikováno v: MedChemComm; 2020, Vol. 11 Issue: 12 p1366-1378, 13p

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Periodical

Rational design, synthesis and testing of novel tricyclic topoisomerase inhibitors for the treatment of bacterial infections part 2Electronic supplementary information (ESI) available. See DOI: 10.1039/d0md00175a

Publikováno v: MedChemComm; 2020, Vol. 11 Issue: 12 p1379-1385, 7p

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Akademický článek

Biological profiling of novel tricyclic inhibitors of bacterial DNA gyrase and topoisomerase IV.

Autor: Savage VJ; Redx Pharma, BioHub, Alderley Park, Cheshire SK10 4TG, UK v.savage@redxpharma.com., Charrier C; Redx Pharma, BioHub, Alderley Park, Cheshire SK10 4TG, UK., Salisbury AM; Redx Pharma, BioHub, Alderley Park, Cheshire SK10 4TG, UK., Moyo E; Redx Pharma, BioHub, Alderley Park, Cheshire SK10 4TG, UK., Forward H; Redx Pharma, BioHub, Alderley Park, Cheshire SK10 4TG, UK., Chaffer-Malam N; Redx Pharma, BioHub, Alderley Park, Cheshire SK10 4TG, UK., Metzger R; Redx Pharma, BioHub, Alderley Park, Cheshire SK10 4TG, UK., Huxley A; Redx Pharma, BioHub, Alderley Park, Cheshire SK10 4TG, UK., Kirk R; Redx Pharma, BioHub, Alderley Park, Cheshire SK10 4TG, UK., Uosis-Martin M; Redx Pharma, BioHub, Alderley Park, Cheshire SK10 4TG, UK., Noonan G; Redx Pharma, BioHub, Alderley Park, Cheshire SK10 4TG, UK., Mohmed S; Redx Pharma, BioHub, Alderley Park, Cheshire SK10 4TG, UK., Best SA; Redx Pharma, BioHub, Alderley Park, Cheshire SK10 4TG, UK., Ratcliffe AJ; Redx Pharma, BioHub, Alderley Park, Cheshire SK10 4TG, UK., Stokes NR; Redx Pharma, BioHub, Alderley Park, Cheshire SK10 4TG, UK.

Publikováno v: The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2016 Jul; Vol. 71 (7), pp. 1905-13. Date of Electronic Publication: 2016 Mar 30.

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Akademický článek

A model system for the synthesis of complanadine alkaloids by "diverted Kondrat'eva" oxazole-olefin cycloaddition.

Autor: Uosis-Martin M; Department of Chemistry, University of Bath, Bath, BA2 7AY, United Kingdom., Pantoş GD, Mahon MF, Lewis SE

Publikováno v: The Journal of organic chemistry [J Org Chem] 2013 Jun 21; Vol. 78 (12), pp. 6253-63. Date of Electronic Publication: 2013 Jun 10.

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Akademický článek

Aliphatic C-H activation with aluminium trichloride-acetyl chloride: expanding the scope of the Baddeley reaction for the functionalisation of saturated hydrocarbons.

Autor: Lyall CL; Department of Chemistry, University of Bath, Bath, UK., Uosis-Martin M, Lowe JP, Mahon MF, Pantoş GD, Lewis SE

Publikováno v: Organic & biomolecular chemistry [Org Biomol Chem] 2013 Mar 07; Vol. 11 (9), pp. 1468-75.

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Akademický článek

Developments in Non-Intercalating Bacterial Topoisomerase Inhibitors: Allosteric and ATPase Inhibitors of DNA Gyrase and Topoisomerase IV.

Autor: Grossman, Scott¹ (AUTHOR) s.grossman@leeds.ac.uk, Fishwick, Colin W. G.¹ (AUTHOR), McPhillie, Martin J.¹ (AUTHOR) s.grossman@leeds.ac.uk

Publikováno v: Pharmaceuticals (14248247). Feb2023, Vol. 16 Issue 2, p261. 17p.

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Akademický článek

Revisiting the Baddeley Reaction: Access to Functionalized Decalins by Charge-Promoted Alkane Functionalization.

Autor: Vavrík M; Institute of Organic Chemistry, University of Vienna, Währinger Straße 38, 1090, Vienna, Austria., Grant PS; Institute of Organic Chemistry, University of Vienna, Währinger Straße 38, 1090, Vienna, Austria., Kaiser D; Institute of Organic Chemistry, University of Vienna, Währinger Straße 38, 1090, Vienna, Austria., Gruene T; Core Facility for Crystal Structure Analysis, University of Vienna, Währinger Straße 42, 1090, Vienna, Austria., Maulide N; Institute of Organic Chemistry, University of Vienna, Währinger Straße 38, 1090, Vienna, Austria.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Nov 08, pp. e202418067. Date of Electronic Publication: 2024 Nov 08.

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