STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses

Autor: Isabelle K. Vila, Hanane Chamma, Alizée Steer, Mathilde Saccas, Clara Taffoni, Evgenia Turtoi, Line S. Reinert, Saqib Hussain, Johanna Marines, Lei Jin, Xavier Bonnefont, Mathieu Hubert, Olivier Schwartz, Soren R. Paludan, Gaetan Van Simaeys, Gilles Doumont, Bijan Sobhian, Dimitrios Vlachakis, Andrei Turtoi, Nadine Laguette

Publikováno v: Cell Metabolism
Cell Metabolism, 2022, 34 (1), pp.125-139.e8. ⟨10.1016/j.cmet.2021.12.007⟩
Vila, I K, Chamma, H, Steer, A, Saccas, M, Taffoni, C, Turtoi, E, Reinert, L S, Hussain, S, Marines, J, Jin, L, Bonnefont, X, Hubert, M, Schwartz, O, Paludan, S R, Van Simaeys, G, Doumont, G, Sobhian, B, Vlachakis, D, Turtoi, A & Laguette, N 2022, ' STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses ', Cell Metabolism, vol. 34, no. 1, pp. 125-139.e8 . https://doi.org/10.1016/j.cmet.2021.12.007
Cell Metabolism, Elsevier, 2022, 34 (1), pp.125-139.e8. ⟨10.1016/j.cmet.2021.12.007⟩

Summary Concerted alteration of immune and metabolic homeostasis underlies several inflammation-related pathologies, ranging from metabolic syndrome to infectious diseases. Here, we explored the coordination of nucleic acid-dependent inflammatory res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbf4272494abb034b39c4311bc04b74d
https://doi.org/10.1016/j.cmet.2021.12.007

A microglial cell model for acyl-CoA oxidase 1 deficiency

Autor: Mustapha Cherkaoui-Malki, Michel Jadot, Stéphane Savary, Quentin Raas, Yannick Hamon, Catherine Gondcaille, Valerio Leoni, Claudio Caccia, Franck Ménétrier, Doriane Trompier, Boubker Nasser, Gérard Lizard, Pierre Andreoletti, Fatima-Ezzahra Saih

Publikováno v: Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids
Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids, 2019, 1864 (4), pp.567-576. ⟨10.1016/j.bbalip.2018.10.005⟩
Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids
Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, Elsevier, 2019, 1864 (4), pp.567-576. ⟨10.1016/j.bbalip.2018.10.005⟩
Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 2019, 1864 (4), pp.567-576. ⟨10.1016/j.bbalip.2018.10.005⟩

Acyl-CoA oxidase 1 (ACOX1) deficiency is a rare and severe peroxisomal leukodystrophy associated with a very long-chain fatty acid (VLCFA) β–oxidation defect. This neurodegenerative disease lacks relevant cell models to further decipher the pathom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6f3ecebeab89d9110a18d1ae1e300d
https://hal.archives-ouvertes.fr/hal-02359450

Quantification and Potential Functions of Endogenous Agonists of Transient Receptor Potential Channels in Patients With Irritable Bowel Syndrome

Autor: Corinne Rolland, Nicholas A. Veldhuis, Jessica Bertrand, Daniel P. Poole, Pauline Le Faouder, Nicolas Cenac, Nathalie Vergnolle, Lisa Zecchi, Tereza Bautzova, Vincenzo Stanghellini, Wolfgang Liedtke, Marc Dubourdeau, Justine Bertrand-Michel, Nigel W. Bunnett, Giovanni Barbara

Publikováno v: Gastroenterology, Vol. 149, No 2 (2015) pp. 433-44.e7

Background & Aims In mice, activation of the transient receptor potential cation channels (TRP) TRPV1, TRPV4, and TRPA1 causes visceral hypersensitivity. These receptors and their agonists might be involved in development of irritable bowel syndrome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af0ebef82cc860b51440105fd898509
https://archive-ouverte.unige.ch/unige:94521

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.