Design and optimization strategies of PROTACs and its Application, Comparisons to other targeted protein degradation for multiple oncology therapies.

Autor: Malarvannan M; Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Kolkata, West Bengal 700054, India., Unnikrishnan S; Department of Pharmaceutical Analysis, Al Shifa College of Pharmacy, Perinthalmanna, Kerala 679325, India., Monohar S; Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Kolkata, West Bengal 700054, India., Ravichandiran V; Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Kolkata, West Bengal 700054, India., Paul D; Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Kolkata, West Bengal 700054, India. Electronic address: davidpaul@niperkolkata.ac.in.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2024 Nov 22; Vol. 154, pp. 107984. Date of Electronic Publication: 2024 Nov 22.