Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Unjoo Lee"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Alcoholic-associated liver disease (ALD) and metabolic dysfunction-associated steatotic liver disease (MASLD) show a high prevalence rate worldwide. As gut microbiota represents current state of ALD and MASLD via gut-liver axis, typical char
Externí odkaz:
https://doaj.org/article/51df071176964bf0a9d1dad0782a28e9
Autor:
Santosh Kumar, Zobia Umair, Vijay Kumar, Ravi Shankar Goutam, Soochul Park, Unjoo Lee, Jaebong Kim
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The Bmp/Smad1 pathway plays a crucial role in developmental processes and tissue homeostasis. Mitogen-activated protein kinase (Mapk)/Erk mediated phosphorylation of Smad1 in the linker region leads to Smad1 degradation, cytoplasmic retentio
Externí odkaz:
https://doaj.org/article/a772200bad67419496b8b1a95d12e036
Autor:
Ingyu Park, Sang-Kyu Lee, Hui-Chul Choi, Moo-Eob Ahn, Ohk-Hyun Ryu, Daehun Jang, Unjoo Lee, Yeo Jin Kim
Publikováno v:
Brain Sciences, Vol 14, Iss 5, p 480 (2024)
In patients with mild cognitive impairment (MCI), a lower level of cognitive function is associated with a higher likelihood of progression to dementia. In addition, gait disturbances and structural changes on brain MRI scans reflect cognitive levels
Externí odkaz:
https://doaj.org/article/07a31a323da840f38844833a862107dd
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Cellular aging is the most severe risk factor for neurodegenerative disease. Simultaneously, oxidative stress (OS) is a critical factor in the aging process, resulting from an imbalance between reactive oxygen and nitrogen species and the antioxidant
Externí odkaz:
https://doaj.org/article/a66a23410fd1476b872071ecfcd24511
Publikováno v:
Cells, Vol 12, Iss 6, p 874 (2023)
The reciprocal inhibition between two signaling centers, the Spemann organizer (dorsal mesoderm) and ventral region (mesoderm and ectoderm), collectively regulate the overall development of vertebrate embryos. Each center expresses key homeobox trans
Externí odkaz:
https://doaj.org/article/fc618b22808145fbab8b3af2128a5e68
Autor:
Zobia Umair, Santosh Kumar, Khezina Rafiq, Vijay Kumar, Zia Ur Reman, Seung-Hwan Lee, SungChan Kim, Jae-Yong Lee, Unjoo Lee, Jaebong Kim
Publikováno v:
Animal Cells and Systems, Vol 24, Iss 6, Pp 359-370 (2020)
Activin, a member of the transforming growth factor (TGF-β) superfamily, induces mesoderm, endoderm and neuro-ectoderm formation in Xenopus embryos. Despite several previous studies, the complicated gene regulatory network and genes involved in this
Externí odkaz:
https://doaj.org/article/f57a4d157cb243c2a52afaeb103ceb31
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0259051 (2021)
BackgroundSeveral studies have reported changes in the corpus callosum (CC) in Alzheimer's disease. However, the involved region differed according to the study population and study group. Using deep learning technology, we ensured accurate analysis
Externí odkaz:
https://doaj.org/article/6d3cc42b23c34ed5a419a2896ead6cea
Autor:
Jaeho Yoon, Vijay Kumar, Ravi Shankar Goutam, Sung-Chan Kim, Soochul Park, Unjoo Lee, Jaebong Kim
Publikováno v:
Cells, Vol 11, Iss 1, p 44 (2021)
Gastrulation is a critical step in the establishment of a basic body plan during development. Convergence and extension (CE) cell movements organize germ layers during gastrulation. Noncanonical Wnt signaling has been known as major signaling that re
Externí odkaz:
https://doaj.org/article/63183c3f503e4016abba2ead8d01962d
Publikováno v:
Journal of Developmental Biology, Vol 9, Iss 4, p 47 (2021)
Germ layer specification and axis formation are crucial events in embryonic development. The Spemann organizer regulates the early developmental processes by multiple regulatory mechanisms. This review focuses on the responsive signaling in organizer
Externí odkaz:
https://doaj.org/article/8a13124fe7d84e40a19a4ac5f3a8d9dd
Publikováno v:
Cells, Vol 10, Iss 10, p 2779 (2021)
Inhibition of the bone morphogenetic proteins (BMPs) is the primary step toward neuroectoderm formation in vertebrates. In this process, the Spemann organizer of the dorsal mesoderm plays a decisive role by secreting several extracellular BMP inhibit
Externí odkaz:
https://doaj.org/article/1511a957c8cb425db4541088a5dceae5