Zobrazeno 1 - 10
of 2 275
pro vyhledávání: '"Unilateral ureteral obstruction"'
Autor:
Divyavani Gowda, Md. Abdul Masum, Siddabasave Gowda B. Gowda, Chandra Shekhar, Md. Zahir Uddin Rubel, Shunnosuke Kira, Osamu Ichii, Yasuhiro Kon, Hitoshi Chiba, Shu-Ping Hui
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Obstructed urine flow is known to cause structural and functional kidney damage leading to renal fibrosis. However, limited information is available on the change in kidney lipids during urinary tract obstruction. In this study, we investiga
Externí odkaz:
https://doaj.org/article/1a207f243d5741da9f3ab3b67c0f4b97
Autor:
Subo Qian, Yongdong Pan, Quan Li, Liying Zhang, Liujian Duan, Yan Xu, Jianwei Cao, Xingang Cui, Yunteng Huang
Publikováno v:
BMC Urology, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Introduction Inflammatory and immunological responses are reported involved in the pathogenesis and progression of obstructive nephropathy (ON). This study was designed to investigate the characteristics of peripheral immunity in patients wi
Externí odkaz:
https://doaj.org/article/d56358fd0a0541848a4a472f5bca75eb
Publikováno v:
Renal Failure, Vol 46, Iss 1 (2024)
Iguratimod is a novel synthetic, small-molecule immunosuppressive agent used to treat rheumatoid arthritis. Through ongoing exploration of its role and mechanisms of action, iguratimod has been observed to have antifibrotic effects in the lung and sk
Externí odkaz:
https://doaj.org/article/c78f9d5d7a3245ca854071fcf65e8e2b
Autor:
Sturla M. Grøndal, Magnus Blø, Linn I. H. Nilsson, Austin J. Rayford, Akil Jackson, Gro Gausdal, James B. Lorens
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe incidence of chronic kidney disease (CKD) is increasing, in parallel with risk factors including obesity and diabetes mellitus. AXL plays a central role in CKD, providing a rationale to evaluate clinical AXL targeting agents.MethodsTo
Externí odkaz:
https://doaj.org/article/fb0ccd45b79b4d14af7b2e872d22b624
Salinomycin attenuates kidney fibrosis and inflammation in mice with unilateral ureteral obstruction
Autor:
Chen, Kuan-Hsing a, b, Hsu, Hsiang-Hao a, Yang, Huang-Yu a, Ko, Yi-Ching a, Hung, Cheng-Chieh a, ⁎
Publikováno v:
In Biochemical and Biophysical Research Communications January 2025 742
Publikováno v:
Tzu-Chi Medical Journal, Vol 36, Iss 1, Pp 59-66 (2024)
Objectives: Ellagic acid (EA), a kind of polyphenol found in numerous fruits and vegetables, has anti-inflammatory, anti-apoptotic, anti-oxidant, and anti-fibrotic effects against a variety of diseases, but its role in mediating renal fibrogenesis re
Externí odkaz:
https://doaj.org/article/571cb66d37a647c5a978a85e9bdc6009
Publikováno v:
Kidney & Blood Pressure Research, Vol 49, Iss 1, Pp 69-80 (2024)
Introduction: Renal fibrosis is a critical event in the development and progression of chronic kidney disease (CKD), and it is considered the final common pathway for all types of CKD. The prevalence of CKD is higher in females; however, males have a
Externí odkaz:
https://doaj.org/article/09e0d46beb354f45a8af8ee4a17d7b1b
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Autor:
Natechanok Thipboonchoo, Somsak Fongsupa, Sanya Sureram, Suliporn Sa-nguansak, Chatchai Kesornpun, Prasat Kittakoop, Sunhapas Soodvilai
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e24983- (2024)
Renal fibrosis is a pathological feature of chronic kidney disease (CKD), progressing toward end-stage kidney disease (ESKD). The aim of this study is to investigate the therapeutic potential of altenusin, a farnesoid X receptor (FXR) agonist derived
Externí odkaz:
https://doaj.org/article/a34a5f2f74874cb3a00e28a2dcc3c7e8
Autor:
Hung, Cheng-Chieh ⁎, Chen, Kuan-Hsing, Hsu, Hsiang-Hao, Chang, Ming-Yang, Ko, Yi-Ching, Yang, Huang-Yu, Yang, Chih-Wei
Publikováno v:
In BBA - Molecular Cell Research January 2024 1871(1)