Cell-cell and cell-substratum contacts in the regulation of MAPK and Akt signalling: Importance in therapy, biopharmacy and bioproduction

Autor: Stulpinas, Aurimas, Uzusienis, Tomas, Imbrasaite, Ausra, Krestnikova, Natalija, Unguryte, Ausra, Kalvelyte, Audrone V.

Publikováno v: In Cellular Signalling August 2021 84

Paracrine Potential of the Human Adipose Tissue-Derived Stem Cells to Modulate Balance between Matrix Metalloproteinases and Their Inhibitors in the Osteoarthritic Cartilage In Vitro

Autor: Jaroslav Denkovskij, Edvardas Bagdonas, Ilona Kusleviciute, Zygmunt Mackiewicz, Ausra Unguryte, Narunas Porvaneckas, Sandrine Fleury, Algirdas Venalis, Christian Jorgensen, Eiva Bernotiene

Publikováno v: Stem Cells International, Vol 2017 (2017)

Adipose tissue represents an abundant source of stem cells. Along with anti-inflammatory effects, ASC secrete various factors that may modulate metabolism of extracellular matrix in osteoarthritic (OA) cartilage, suggesting that the presence of ASC c

Externí odkaz: https://doaj.org/article/a189ad30de8e4dd291ca43a69863df5e

Cell-cell and cell-substratum contacts in the regulation of MAPK and Akt signalling: Importance in therapy, biopharmacy and bioproduction

Autor: Ausra Unguryte, Audrone Kalvelyte, Aurimas Stulpinas, Ausra Imbrasaite, Natalija Krestnikova, Tomas Uzusienis

Publikováno v: Cellular Signalling. 84:110034

The use of cultured cells as a tool for research, precision medicine, biopharmacy, and biomanufacturing is constantly increasing. In parallel, the role of cell-cell and cell-substratum contacts in cell functioning is increasingly validated. Adhesion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ae573ae3d65f6f4e785ca1e47e86c79
https://doi.org/10.1016/j.cellsig.2021.110034

Paracrine potential of the human adipose tissue-derived stem cells to modulate balance between matrix metalloproteinases and their inhibitors in the osteoarthritic cartilage in vitro

Autor: Zygmunt Mackiewicz, Ausra Unguryte, Eiva Bernotiene, Edvardas Bagdonas, Algirdas Venalis, Narunas Porvaneckas, Sandrine Fleury, Christian Jorgensen, Jaroslav Denkovskij, Ilona Kusleviciute

Publikováno v: Stem cells international, London : Hindawi LTD, 2017, vol. 2017, art. no. 9542702, p. [1-14]
Stem Cells International
Stem Cells International, Hindawi Publishing Corporation, 2017, 2017, pp.9542702. ⟨10.1155/2017/9542702⟩
Stem Cells International, Vol 2017 (2017)

Adipose tissue represents an abundant source of stem cells. Along with anti-inflammatory effects, ASC secrete various factors that may modulate metabolism of extracellular matrix in osteoarthritic (OA) cartilage, suggesting that the presence of ASC c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee9ca82e1b2827edf5b707ac19629ef2
https://repository.vu.lt/VU:ELABAPDB48999829&prefLang=en_US

Human articular chondrocytes with higher aldehyde dehydrogenase activity have stronger expression of COL2A1 and SOX9

Autor: Christian Jorgensen, Eiva Bernotiene, Edvardas Bagdonas, Ausra Unguryte, Narūnas Porvaneckas, S. Garberyte

Publikováno v: Osteoarthritis and Cartilage
Osteoarthritis and Cartilage, Elsevier, 2016, 24 (5), pp.873-882. ⟨10.1016/j.joca.2015.11.019⟩

Summary Objective To determine in human articular chondrocytes the activity of Aldehyde dehydrogenase (ALDH), which are reported as stem/progenitor cell marker in various adult tissues and evaluate gene expression of ALDH1A isoforms. Design ALDH acti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3902cb899e39f17f70370fdcf1a2cc
https://pubmed.ncbi.nlm.nih.gov/26687820