Monitoring disease evolution and treatment response in lysosomal disorders by the peripheral benzodiazepine receptor ligand PK11195

Autor: Visigalli I. 1, 2, Moresco R.M. 3, 6, 7, Belloli S. 3, Politi L.S. 2, 4, Gritti A. 1, Ungaro D. 5, Matarrese M, 3, Turolla E. 3, Falini A. 2, Scotti G. 1, Naldini L. 1, Fazio F. 3, Biffi A.1

Publikováno v: Neurobiology of disease 34 (2009): 51–62.
info:cnr-pdr/source/autori:Visigalli I. 1,2, Moresco R.M. 3,6,7, Belloli S. 3,6,7, Politi L.S. 2,4, Gritti A. 1, Ungaro D. 5, Matarrese M, 3,6,7, Turolla E. 3,6,7, Falini A. 2,4, Scotti G. 1,2, Naldini L. 1,2, Fazio F. 3,7, Biffi A.1,2/titolo:Monitoring disease evolution and treatment response in lysosomal disorders by the peripheral benzodiazepine receptor ligand PK11195./doi:/rivista:Neurobiology of disease/anno:2009/pagina_da:51/pagina_a:62/intervallo_pagine:51–62/volume:34

Microglia activation and neuroinflammation play a pivotal role in the pathogenesis of lysosomal storage disorders (LSD) affecting the central nervous system (CNS), which are amenable to treatment by hematopoietic stem cell transplantation (HSCT). HSC

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https://publications.cnr.it/doc/10424