Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ung Seop Jeon"'
Autor:
Rachel Y. Chow, Ung Seop Jeon, Taylor M. Levee, Gurleen Kaur, Daniel P. Cedeno, Linda T. Doan, Scott X. Atwood
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Basal cell carcinoma (BCC) is a locally invasive epithelial cancer that is primarily driven by the Hedgehog (HH) pathway. Advanced BCCs are a critical subset of BCCs that frequently acquire resistance to Smoothened (SMO) inhibitors and identifying pa
Externí odkaz:
https://doaj.org/article/57512013145247da8da7a1914cb3b3af
Autor:
Whitney England, Vama Jhumkhawala, Linda Doan, Kevin C. Tan, Tuyen T. L. Nguyen, Robert C. Spitale, Vinay Kumar, Ung Seop Jeon, Scott X. Atwood
Primary cilia loss is a common feature of advanced cancers. While primary cilia are necessary to initiate Hedgehog (HH)-driven cancers, how HH pathway activity is maintained in advanced cancers devoid of primary cilia is unclear. Here, we find that H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53c1558e92ece401e845f91daffefcbc
https://doi.org/10.1101/2020.06.08.137216
https://doi.org/10.1101/2020.06.08.137216
