Validation of a Preclinical Drug Screening Platform for Pharmacoresistant Epilepsy.

Autor: Barker-Haliski ML; Department of Pharmacy, University of Washington, Seattle, WA, 98195, USA. mhaliski@uw.edu., Johnson K; Anticonvulsant Drug Development Program, University of Utah, Salt Lake City, UT, 84112, USA., Billingsley P; Anticonvulsant Drug Development Program, University of Utah, Salt Lake City, UT, 84112, USA., Huff J; Anticonvulsant Drug Development Program, University of Utah, Salt Lake City, UT, 84112, USA., Handy LJ; Anticonvulsant Drug Development Program, University of Utah, Salt Lake City, UT, 84112, USA., Khaleel R; Anticonvulsant Drug Development Program, University of Utah, Salt Lake City, UT, 84112, USA., Lu Z; Anticonvulsant Drug Development Program, University of Utah, Salt Lake City, UT, 84112, USA., Mau MJ; Anticonvulsant Drug Development Program, University of Utah, Salt Lake City, UT, 84112, USA., Pruess TH; Anticonvulsant Drug Development Program, University of Utah, Salt Lake City, UT, 84112, USA., Rueda C; Anticonvulsant Drug Development Program, University of Utah, Salt Lake City, UT, 84112, USA., Saunders G; Anticonvulsant Drug Development Program, University of Utah, Salt Lake City, UT, 84112, USA., Underwood TK; Anticonvulsant Drug Development Program, University of Utah, Salt Lake City, UT, 84112, USA., Vanegas F; Anticonvulsant Drug Development Program, University of Utah, Salt Lake City, UT, 84112, USA., Smith MD; Anticonvulsant Drug Development Program, University of Utah, Salt Lake City, UT, 84112, USA.; Department of Pharmacology & Toxicology, University of Utah, Salt Lake City, UT, 84112, USA., West PJ; Anticonvulsant Drug Development Program, University of Utah, Salt Lake City, UT, 84112, USA.; Department of Pharmacology & Toxicology, University of Utah, Salt Lake City, UT, 84112, USA., Wilcox KS; Anticonvulsant Drug Development Program, University of Utah, Salt Lake City, UT, 84112, USA.; Department of Pharmacology & Toxicology, University of Utah, Salt Lake City, UT, 84112, USA.

Publikováno v: Neurochemical research [Neurochem Res] 2017 Jul; Vol. 42 (7), pp. 1904-1918. Date of Electronic Publication: 2017 Mar 16.

Quantification of cerivastatin toxicity supports organismal performance assays as an effective tool during pharmaceutical safety assessment.

Autor: Gaukler SM; Department of Biology University of Utah Salt Lake City UT USA; Los Alamos National Laboratory Environmental Stewardship Group Los Alamos NM USA., Ruff JS; Department of Biology University of Utah Salt Lake City UT USA., Galland T; Department of Biology University of Utah Salt Lake City UT USA., Underwood TK; Department of Biology University of Utah Salt Lake City UT USA., Kandaris KA; Department of Biology University of Utah Salt Lake City UT USA., Liu NM; Department of Biology University of Utah Salt Lake City UT USA., Morrison LC; Department of Biology University of Utah Salt Lake City UT USA., Veranth JM; Department of Pharmacology and Toxicology University of Utah Salt Lake City UT USA., Potts WK; Department of Biology University of Utah Salt Lake City UT USA.

Publikováno v: Evolutionary applications [Evol Appl] 2016 Apr 15; Vol. 9 (5), pp. 685-96. Date of Electronic Publication: 2016 Apr 15 (Print Publication: 2016).