Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Understanding and Treating Chlorine-induced Lung Injury"'
Autor:
Sven-Eric Jordt, Bret F. Bessac
Publikováno v:
Proceedings of the American Thoracic Society. 7:269-277
The inhalation of reactive gases and vapors can lead to severe damage of the airways and lung, compromising the function of the respiratory system. Exposures to oxidizing, electrophilic, acidic, or basic gases frequently occur in occupational and amb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049683a64bc1970a24b4aabe00f45594
https://doi.org/10.1513/pats.201001-004sm
https://doi.org/10.1513/pats.201001-004sm
Autor:
Daniel R. Prows, Qian Li, Kiflai Bein, An-Soo Jang, Hannah Pope-Varsalona, Kelly A. Brant, Vincent J. Concel, Naftali Kaminski, Pengyuan Liu, George D. Leikauf, Richard A. Dopico, Louis J. Vuga, Ming You, Mario Medvedovic, Y. Peter Di, Maggie Dietsch
Publikováno v:
Proceedings of the American Thoracic Society. 7:294-296
Acute lung injury can be induced indirectly (e.g., sepsis) or directly (e.g., chlorine inhalation). Because treatment is still limited to supportive measures, mortality remains high ( approximately 74,500 deaths/yr). In the past, accidental (railroad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a82904eb69ddf2815dafb3d7d291d8a8
https://doi.org/10.1513/pats.201001-005sm
https://doi.org/10.1513/pats.201001-005sm
Autor:
David A. Jett, David T. Yeung
Publikováno v:
Proceedings of the American Thoracic Society. 7:254-256
The National Institutes of Health has developed a comprehensive research program that includes research centers of excellence, individual research projects, small business projects, contracts, and interagency agreements to conduct basic, translationa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbf8092ebdd7273563392cfe870af351
https://doi.org/10.1513/pats.201001-003sm
https://doi.org/10.1513/pats.201001-003sm
Autor:
Carl W. White, James G. Martin
Publikováno v:
Proceedings of the American Thoracic Society. 7(4)
Humans can come into contact with chlorine gas during short-term, high-level exposures due to traffic or rail accidents, spills, or other disasters. By contrast, workplace and public (swimming pools, etc.) exposures are more frequently long-term, low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd4c560df06fd7f9ade46ca04523cec
https://pubmed.ncbi.nlm.nih.gov/20601629
https://pubmed.ncbi.nlm.nih.gov/20601629
Autor:
Sadis Matalon, Edward M. Postlethwait, Stephen F. Doran, Andreas Bracher, Martin Leustik, Amit K. Yadav, Giuseppe L. Squadrito
Publikováno v:
Proceedings of the American Thoracic Society. 7(4)
Chlorine (Cl(2)) is a reactive oxidant gas used extensively in industrial processes. Exposure of both humans and animals to high concentrations of Cl(2) results in acute lung injury, which may resolve spontaneously or progress to acute respiratory fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2b57fb04b5297fa779616364753a33
https://pubmed.ncbi.nlm.nih.gov/20601632
https://pubmed.ncbi.nlm.nih.gov/20601632
Exposure to chlorine gas (Cl(2)) primarily causes injury to the lung and is characterized by inflammation and oxidative stress mediated by reactive chlorine species. Reducing lung injury and improving respiratory function are the principal therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e6724284e14be8fb1af1b1079e65853
https://europepmc.org/articles/PMC3136966/
https://europepmc.org/articles/PMC3136966/
Autor:
Gary W. Hoyle
Chlorine is considered a chemical threat agent to which humans may be exposed as a result of accidental or intentional release. Chlorine is highly reactive, and inhalation of the gas causes cellular damage to the respiratory tract, inflammation, pulm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019332ededdc7cf87f92caf1ce95d00e
https://europepmc.org/articles/PMC3136965/
https://europepmc.org/articles/PMC3136965/
Autor:
Roy J. Rando, Edward M. Postlethwait, Yung Sung Cheng, Sadis Matalon, Giuseppe L. Squadrito, Larry E. Bowen
Inhalation experiments using laboratory animals are performed under controlled conditions to assess the toxicity of and to investigate interventional strategies to ameliorate injury resulting from oxidant gas exposures. A variety of dynamic inhalatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d7a4daf5bf937248243208fb8f48fd
https://europepmc.org/articles/PMC3136962/
https://europepmc.org/articles/PMC3136962/