Zobrazeno 1 - 10
of 234
pro vyhledávání: '"Unconventional T cells"'
Publikováno v:
Data in Brief, Vol 56, Iss , Pp 110786- (2024)
Mucosal-associated invariant T (MAIT) cells represent a unique unconventional T cell population important in eliciting immunomodulatory responses in a range of diseases, including infectious diseases, autoimmunity and cancer. This innate-like T cell
Externí odkaz:
https://doaj.org/article/85aa6affd00e46bcae20680cfbafbc7b
Autor:
Daniel G. Pellicci, Naeimeh Tavakolinia, Louis Perriman, Stuart P. Berzins, Christopher Menne
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Invariant natural killer T (iNKT) cells are a subset of lipid-reactive, unconventional T cells that have anti-tumor properties that make them a promising target for cancer immunotherapy. Recent studies have deciphered the developmental pathway of hum
Externí odkaz:
https://doaj.org/article/c1de806c8b184af89096bcb32a7a2ebc
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Adoptive cellular immunotherapy as a new paradigm to treat cancers is exemplified by the FDA approval of six chimeric antigen receptor-T cell therapies targeting hematological malignancies in recent years. Conventional αβ T cells applied in these t
Externí odkaz:
https://doaj.org/article/69472357978f47b8999c2bb0edaf4ee0
Autor:
Michael Manoharan Valerio, Kathya Arana, Jian Guan, Shiao Wei Chan, Xiaokun Yang, Nadia Kurd, Angus Lee, Nilabh Shastri, Laurent Coscoy, Ellen A. Robey
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
MHC-E restricted CD8 T cells show promise in vaccine settings, but their development and specificity remain poorly understood. Here we focus on a CD8 T cell population reactive to a self-peptide (FL9) bound to mouse MHC-E (Qa-1b) that is presented in
Externí odkaz:
https://doaj.org/article/39ecc32a95a34e96b4b07cd3ca823fbb
Autor:
Ramon A. Lujan, Luxin Pei, John P. Shannon, Nathânia Dábilla, Patrick T. Dolan, Heather D. Hickman
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
After recognition of cognate antigen (Ag), effector CD8+ T cells secrete serine proteases called granzymes in conjunction with perforin, allowing granzymes to enter and kill target cells. While the roles for some granzymes during antiviral immune res
Externí odkaz:
https://doaj.org/article/7c0fe53a5ce04007a06470d8bca5d607
Akademický článek
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Autor:
Erik D. Hanson, Samy Sakkal, Lauren C. Bates-Fraser, Shadney Que, Eunhan Cho, Guillaume Spielmann, Elif Kadife, John A. Violet, Claudio L. Battaglini, Lee Stoner, David B. Bartlett, Glenn K. McConell, Alan Hayes
Publikováno v:
Frontiers in Sports and Active Living, Vol 5 (2023)
BackgroundReduced testosterone levels can influence immune system function, particularly T cells. Exercise during cancer reduces treatment-related side effects and provide a stimulus to mobilize and redistribute immune cells. However, it is unclear h
Externí odkaz:
https://doaj.org/article/e542ae7e8af74c2e8b552d2d8fe126f9
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
In the last years, the tumor microenvironment (TME) has emerged as a promising target for therapeutic interventions in cancer. Cancer cells are highly dependent on the TME to growth and evade the immune system. Three major cell subpopulations are fac
Externí odkaz:
https://doaj.org/article/8ce8e6ff3cc34a5dac524eda9c72addb
Autor:
Daniel R Labuz, Giavonni Lewis, Irma D Fleming, Callie M Thompson, Yan Zhai, Matthew A Firpo, Daniel T Leung
Publikováno v:
eLife, Vol 12 (2023)
Burn injuries are a leading cause of unintentional injury, associated with a dysfunctional immune response and an increased risk of infections. Despite this, little is known about the role of T cells in human burn injury. In this study, we compared t
Externí odkaz:
https://doaj.org/article/bb21d4530b43465091764caf3fc3846b
Akademický článek
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