Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Unbin Chae"'
Autor:
Hanseop Kim, Bokyung Kim, Unbin Chae, Young-Ho Park, Dong-Seok Lee, Sun-Uk Kim, Seung-Hwan Lee
Publikováno v:
Journal of Biological Research
Background Peroxiredoxins (Prxs) are antioxidant enzymes that protect cells from oxidative stress induced by several factors. They regulate several signaling pathways, such as metabolism, immune response, and intracellular reactive oxygen species (RO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46fbe48747880e23ceb3668fc8b2bcfb
https://doi.org/10.1186/s40709-021-00153-6
https://doi.org/10.1186/s40709-021-00153-6
Publikováno v:
Aging (Albany NY)
Among the many factors that promote cellular senescence, reactive oxygen species (ROS) are a focus of intense research because of their critical role in accelerating cellular senescence and initiating senescence-related diseases that can be fatal. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5b459bd8a5990db037348403bcb3721
http://europepmc.org/articles/PMC6756887
http://europepmc.org/articles/PMC6756887
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 83:409-416
Microglial activation is known to be an important event during innate immunity, but microglial inflammation is also thought to play a role in the etiology of neurodegenerative diseases. Recently, it was reported that autophagy could influence inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31054873c1ec7fb8f843556de009a0b9
https://doi.org/10.1080/09168451.2018.1549933
https://doi.org/10.1080/09168451.2018.1549933
Autor:
Hae-Jun, Yang, Bong-Seok, Song, Bo-Woong, Sim, Yena, Jung, Unbin, Chae, Dong Gil, Lee, Jae-Jin, Cha, Seo-Jong, Baek, Kyung Seob, Lim, Won Seok, Choi, Hwal-Yong, Lee, Hee-Chang, Son, Sung-Hyun, Park, Kang-Jin, Jeong, Philyong, Kang, Seung Ho, Baek, Bon-Sang, Koo, Han-Na, Kim, Yeung Bae, Jin, Young-Ho, Park, Young-Kug, Choo, Sun-Uk, Kim
Publikováno v:
International Journal of Molecular Sciences
In recent decades, many studies on the treatment and prevention of pancreatic cancer have been conducted. However, pancreatic cancer remains incurable, with a high mortality rate. Although mouse models have been widely used for preclinical pancreatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::73d6f8319d74af6b3c72724bf2321e74
https://pubmed.ncbi.nlm.nih.gov/33233448
https://pubmed.ncbi.nlm.nih.gov/33233448
Autor:
Unbin Chae, Kyung-Min Kim, Hyun-Shik Lee, Heejin Lee, Han Seop Kim, Jeen-Woo Park, Dong-Seok Lee
Publikováno v:
Inflammation. 41:1965-1973
In various neuronal diseases, the activation of microglia contributes to the production of excessive neurotoxic factors, such as pro-inflammatory mediators. In particular, the overproduction of pro-inflammatory cytokines and nitric oxide (NO) has cri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9221b76ba0ce2e9d3335494fda3e5b93
https://doi.org/10.1007/s10753-018-0840-5
https://doi.org/10.1007/s10753-018-0840-5
Autor:
Je-Yong Choi, Kim Es, Lee Hs, Na-Rae Park, Dong-Seok Lee, Unbin Chae, Lee S, Lee, Yim M, Park Jw
Publikováno v:
Physiological Research. :487-494
Spinal deformities such as scoliosis and kyphosis are incurable, and can lead to decreased physical function, pain, and reduced quality of life. Despite much effort, no clear therapies for the treatment of these conditions have been found. Therefore,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ac726e249c5bba93ac2b333b59a0cf
https://doi.org/10.33549/physiolres.933711
https://doi.org/10.33549/physiolres.933711
Autor:
Hyun-Shik Lee, Jung-Hak Kim, Joongbae Seong, Dong-Seok Lee, Sang-Rae Lee, Unbin Chae, Sun-Ji Park, Seung-Hoon Lee
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 99:80-90
Insulin signaling is essential for regulating glucose homeostasis. Numerous studies have demonstrated that reactive oxygen species (ROS) affect insulin signaling, and low ROS levels can act as a signal to regulate cellular function. Peroxiredoxins (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98132832c7a827d8abec49b69a72d2de
https://doi.org/10.1016/j.biocel.2018.03.019
https://doi.org/10.1016/j.biocel.2018.03.019
Autor:
Seung-Hoon Lee, Dong Gil Lee, Sang-Rae Lee, Min Kyoung Kam, Unbin Chae, Hyun-Shik Lee, Junghyung Park, Jeen-Woo Park, Bokyung Kim, Dong-Seok Lee
Publikováno v:
Antioxidants & Redox Signaling. 27:715-726
Aims: Aberrant Cdk5 (cyclin-dependent kinase 5) and oxidative stress are crucial components of diverse neurodegenerative disorders, including Alzheimer's disease (AD). We previously reported that a change in peroxiredoxin (Prx) expression is associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25487fada6975cf72f7560fc22aad19d
https://doi.org/10.1089/ars.2016.6810
https://doi.org/10.1089/ars.2016.6810
Autor:
Unbin Chae, Heejin Lee, Dong-Seok Lee, Ann-Hwee Lee, Haiyoung Jung, Bokyung Kim, Byeong Mo Kim, Sang-Hyun Min
Publikováno v:
Oncogenesis, Vol 8, Iss 3, Pp 1-10 (2019)
Oncogenesis
Oncogenesis
In cancer, activation of X-box binding protein (XBP1) has a critical role in tumorigenesis and cancer progression. Transcriptional regulatory mechanism of XBP1 in cancer development has been well known, however, regulation of ubiquitination and degra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf1568781b005fa40078265bbeaddaa8
https://doi.org/10.1038/s41389-019-0124-4
https://doi.org/10.1038/s41389-019-0124-4
Autor:
Hyun-Shik Lee, Hong Jun Lee, Ju-Sik Min, Unbin Chae, Sang-Rae Lee, Hyun Hee Leem, Dong-Seok Lee
Publikováno v:
Pharmacology. 100:153-160
Chrysophanic acid, or chrysophanol, is an anthraquinone found in Rheum palmatum, which was used in the preparation of oriental medicine in ancient China. The hippocampus plays a major role in controlling the activities of the short- and long-term mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::280e2cc430376abec8bb8e45a82b7282
https://doi.org/10.1159/000477814
https://doi.org/10.1159/000477814