PK/PD modeling and simulation of the in vitro activity of the combinations of isavuconazole with echinocandins against Candida auris

Autor: Unai Caballero, Elena Eraso, Guillermo Quindós, Valvanera Vozmediano, Stephan Schmidt, Nerea Jauregizar

Publikováno v: CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 6, Pp 770-782 (2023)

Abstract In vitro combination of echinocandins and isavuconazole against the emerging species Candida auris is mainly synergistic. However, this combination has not been evaluated in clinical settings. A pharmacokinetic/pharmacodynamic modeling and s

Externí odkaz: https://doaj.org/article/c5d5753bcfc74921aed47867cd1ff918

In Vitro Interaction and Killing-Kinetics of Amphotericin B Combined with Anidulafungin or Caspofungin against Candida auris

Autor: Unai Caballero, Elena Eraso, Guillermo Quindós, Nerea Jauregizar

Publikováno v: Pharmaceutics, Vol 13, Iss 9, p 1333 (2021)

Treatment of invasive infections caused by Candida auris is challenging due to the limited therapeutic options. The combination of antifungal drugs may be an interesting and feasible approach to be investigated. The aim of this study was to examine t

Externí odkaz: https://doaj.org/article/fff22c1549384b2484a8096577a6569a

PK / PD modeling and simulation of the in vitro activity of the combinations of isavuconazole with echinocandins against Candida auris

Autor: Unai Caballero, Elena Eraso, Guillermo Quindós, Valvanera Vozmediano, Stephan Schmidt, Nerea Jauregizar

Publikováno v: CPT: Pharmacometrics & Systems Pharmacology.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f67c317b1e36abcae8b363e786087da9
https://doi.org/10.1002/psp4.12949

In Vitro Synergistic Interactions of Isavuconazole and Echinocandins against Candida auris

Autor: Valvanera Vozmediano, Sarah Kim, Unai Caballero, Stephan Schmidt, Elena Eraso, Guillermo Quindós, Nerea Jauregizar

Publikováno v: Addi. Archivo Digital para la Docencia y la Investigación
instname
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Antibiotics
Volume 10
Issue 4
Antibiotics, Vol 10, Iss 355, p 355 (2021)

Candida auris is an emergent fungal pathogen that causes severe infectious outbreaks globally. The public health concern when dealing with this pathogen is mainly due to reduced susceptibility to current antifungal drugs. A valuable alternative to ov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a17c6d7f0964588c9a91ca00c082bd74
http://hdl.handle.net/10810/51195