Zobrazeno 1 - 10
of 207
pro vyhledávání: '"Un Kyung Kim"'
Publikováno v:
Clinical and Experimental Otorhinolaryngology, Vol 16, Iss 4, Pp 403-406 (2023)
Externí odkaz:
https://doaj.org/article/aaf8a182e944465187f8ae1cf8dca73a
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Noise (noise-induced hearing loss), and ototoxic drugs (drug-induced ototoxicity), and aging (age-related hearing loss) are the major environmental factors that lead to acquired sensorineural hearing loss. So far, there have been numerous efforts to
Externí odkaz:
https://doaj.org/article/a3d0e51d29674af1b845290dbfdf490f
Autor:
Jin-Mo Park, Byeonghyeon Lee, Jong-Heun Kim, Seong-Yong Park, Jinhoon Yu, Un-Kyung Kim, Jin-Sung Park
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-6 (2020)
Abstract Hereditary spastic paraplegia (HSP) is a heterogeneous inherited disorder that manifests with lower extremity weakness and spasticity. HSP can be inherited by autosomal dominant, autosomal recessive, and X-linked inheritance patterns. Recent
Externí odkaz:
https://doaj.org/article/6712f85ae685492d94fdef7200c71607
Publikováno v:
Free Radical Biology and Medicine. 204:177-183
Autor:
Min-A Kim, Nari Ryu, Hye-Min Kim, Ye-Ri Kim, Byeonghyeon Lee, Tae-Jun Kwon, Jinwoong Bok, Un-Kyung Kim
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 13, Iss , Pp 197-204 (2019)
Targeting specific cell types in the mammalian inner ear is important for treating genetic hearing loss due to the different cell type-specific functions. Adeno-associated virus (AAV) is an efficient in vivo gene transfer vector, and it has demonstra
Externí odkaz:
https://doaj.org/article/b7c1714cb9374824b6a5cf08af193951
Autor:
Ye-Ri Kim, Jeong-In Baek, Sung Hwan Kim, Min-A Kim, Byeonghyeon Lee, Nari Ryu, Kyung-Hee Kim, Deok-Gyun Choi, Hye-Min Kim, Michael P. Murphy, Greg Macpherson, Yeon-Sik Choo, Jinwoong Bok, Kyu-Yup Lee, Jeen-Woo Park, Un-Kyung Kim
Publikováno v:
Redox Biology, Vol 20, Iss , Pp 544-555 (2019)
Mitochondrial NADP+-dependent isocitrate dehydrogenase 2 (IDH2) is a major NADPH-producing enzyme which is essential for maintaining the mitochondrial redox balance in cells. We sought to determine whether IDH2 deficiency induces mitochondrial dysfun
Externí odkaz:
https://doaj.org/article/d71b374266564676820b6c5f775c1afa
Autor:
Ye-Ri Kim, Hye-Min Kim, Byeonghyeon Lee, Jeong-In Baek, Kyu-Yup Lee, Hong-Joon Park, Un-Kyung Kim
Publikováno v:
Genes & Genomics. 45:225-230
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 126, Iss , Pp 110068- (2020)
Cisplatin (CP) is a chemotherapeutic drug used to treat cancerous solid tumors, but it causes serious side effects, including ototoxicity. The major cause of CP-induced ototoxicity is increased levels of mitochondrial reactive oxygen species (ROS). I
Externí odkaz:
https://doaj.org/article/ebf8c0bc69334820a40cac0cf665d8ce
Publikováno v:
Antioxidants, Vol 10, Iss 10, p 1526 (2021)
Drug-induced hearing loss is a major type of acquired sensorineural hearing loss. Cisplatin and aminoglycoside antibiotics have been known to cause ototoxicity, and excessive accumulation of intracellular reactive oxygen species (ROS) are suggested a
Externí odkaz:
https://doaj.org/article/f2650db040cc4ed6a0637364de6b2d07
Publikováno v:
Clinical and Experimental Otorhinolaryngology, Vol 10, Iss 1, Pp 50-55 (2017)
Objectives We aimed to identify the causative mutation for siblings in a Korean family with nonsyndromic hearing loss (HL) and enlarged vestibular aqueduct (EVA). The siblings were a 19-year-old female with bilateral profound HL and an 11-year-old ma
Externí odkaz:
https://doaj.org/article/75f6584811be4f5ca597ba2900318d45