Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Umut Oguz"'
Autor:
Philip G Wong, Sherry L Winter, Elena Zaika, Thinh V Cao, Umut Oguz, John M Koomen, Joyce L Hamlin, Mark G Alexandrow
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17533 (2011)
Little is known about mammalian preRC stoichiometry, the number of preRCs on chromosomes, and how this relates to replicon size and usage. We show here that, on average, each 100-kb of the mammalian genome contains a preRC composed of approximately o
Externí odkaz:
https://doaj.org/article/de18e5b1d85143e8874f041b4eb79e3a
Autor:
Yun Bai, Fumi Kinose, Eric A. Welsh, Uwe Rix, Eric B. Haura, Amer A. Beg, Steven A. Eschrich, Bin Fang, Lily L. Remsing Rix, Crystina C. Bronk, Umut Oguz, John M. Koomen, Jae-Young Kim
Publikováno v:
Proceedings of the National Academy of Sciences. 110:12414-12419
TANK-binding kinase 1 (TBK1) has emerged as a novel therapeutic target for unspecified subset of lung cancers. TBK1 reportedly mediates prosurvival signaling by activating NF-κB and AKT. However, we observed that TBK1 knockdown also decreased viabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7da06381e6a28146c50828c8056220b
https://doi.org/10.1073/pnas.1220674110
https://doi.org/10.1073/pnas.1220674110
Autor:
Fumi Kinose, Bin Fang, John M. Koomen, Jiannong Li, Elizabeth R. Remily-Wood, Umut Oguz, Richard Z. Liu, Eric B. Haura, Steven A. Eschrich, Hui-Yi Lin, Soner Altiok, Guolin Zhang, Yun Bai
Publikováno v:
Journal of Proteome Research. 10:305-319
The epidermal growth factor receptor (EGFR) plays an important role in cancer by activating downstream signals important in growth and survival. Inhibitors of EGFR are frequently selected as treatment for cancer including lung cancer. We performed an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8cf5f64968aaf58b4d944bdbb34f988
https://doi.org/10.1021/pr1006203
https://doi.org/10.1021/pr1006203
Autor:
Engin U. Akkaya, Umut Oguz
Publikováno v:
Tetrahedron Letters. 39:5857-5860
A novel squaraine with a lariat-crown ether cation-receptor unit was synthesized and shown to selectively respond to Na + ions in polar protic solvents. The selectivity of the novel ligand, together with the impressive spectroscopic properties of squ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d94afd7f8ad112698aedc380a30e3c1
https://doi.org/10.1016/s0040-4039(98)01165-4
https://doi.org/10.1016/s0040-4039(98)01165-4
Autor:
Umut Oguz, Engin U. Akkaya
Publikováno v:
Tetrahedron Letters. 38:4509-4512
A long wavelength fluorescent, squaraine-based chemosensor has been synthesized in one step from commercially available precursors. The resulting squaraine derivative absorbs maximally at 635 nm ( e = 260,000) and the emission peak is at 665 nm. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29848952e228288592592e5c3b849123
https://doi.org/10.1016/s0040-4039(97)00916-7
https://doi.org/10.1016/s0040-4039(97)00916-7
Publikováno v:
Tetrahedron Letters. 43:2873-2875
A convenient route to make α-hydrazino esters from their corresponding α-amino esters is reported. A key step is selective nitrosamine reduction using activated Zn, conc. HCl, and methanol at low temperatures giving nearly quantitative yields of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a70391869336c5baceae4ae5494136d0
https://doi.org/10.1016/s0040-4039(02)00352-0
https://doi.org/10.1016/s0040-4039(02)00352-0
Publikováno v:
ChemInform. 33
A convenient route to make α-hydrazino esters from their corresponding α-amino esters is reported. A key step is selective nitrosamine reduction using activated Zn, conc. HCl, and methanol at low temperatures giving nearly quantitative yields of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c0619f36032c928560129fd30f38a89
https://doi.org/10.1002/chin.200230229
https://doi.org/10.1002/chin.200230229
Autor:
Eric A. Welsh, Jiannong Li, Eric B. Haura, Ann Chen, Crystina C. Bronk, Fumi Kinose, Amer A. Beg, Bin Fang, Umut Oguz, Jae-Young Kim, Steven A. Eschrich, John M. Koomen
Publikováno v:
Cancer Research. 73:937-937
KRAS mutation accounts for development of approximately 30% of lung adenocarcinoma yet therapeutic options remain limited. We report our efforts to explore downstream signaling proteins driven by KRAS, including TANK-binding kinase 1 (TBK1), through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6f932a8f04a997295154d8646c48e76
https://doi.org/10.1158/1538-7445.am2013-937
https://doi.org/10.1158/1538-7445.am2013-937
Autor:
Umut Oguz, Engin U. Akkaya
Publikováno v:
The Journal of organic chemistry. 63(17)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2808a5065536f1ed163a2f6cadf32de0
https://pubmed.ncbi.nlm.nih.gov/11672218
https://pubmed.ncbi.nlm.nih.gov/11672218
Autor:
Jessica Gancar, John M. Koomen, Christopher L. Cubitt, Kenneth H. Shain, Umut Oguz, William S. Dalton, Elizabeth R. Wood, Yun Xiang
Publikováno v:
Cancer Research. 71:5112-5112
Introduction: Proteomic analyses using iTRAQ and reaction monitoring mass spectrometry are used to examine the mechanism of melphalan resistance and build an assessment platform to enable future selection of combination therapy in patients. Experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::859bc053193550dc7eb0f42f047f877a
https://doi.org/10.1158/1538-7445.am2011-5112
https://doi.org/10.1158/1538-7445.am2011-5112