Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Umut Akinci"'
Autor:
Ksenija Drabek, Laura Gutiérrez, Marcel Vermeij, Thomas Clapes, Sunita R. Patel, Jean-Charles Boisset, Jeffrey van Haren, Ana L. Pereira, Zhe Liu, Umut Akinci, Tatjana Nikolic, Wilfred van IJcken, Mirjam van den Hout, Marjolein Meinders, Clara Melo, Clara Sambade, Dubravka Drabek, Rudi W. Hendriks, Sjaak Philipsen, Mieke Mommaas, Frank Grosveld, Helder Maiato, Joseph E. Italiano, Jr., Catherine Robin, Niels Galjart
Publikováno v:
Cell Reports, Vol 2, Iss 4, Pp 781-788 (2012)
Mammalian CLASPs are microtubule plus-end tracking proteins whose essential function as regulators of microtubule behavior has been studied mainly in cultured cells. We show here that absence of murine CLASP2 in vivo results in thrombocytopenia, prog
Externí odkaz:
https://doaj.org/article/3e5cff7148ce447398adad76a986d785
Autor:
Maaike J. Moen, Johannes H. Brandsma, Raymond A. Poot, W F J van IJcken, D. H. W. Dekkers, Hieab H.H. Adams, S Karkampouna, Christel E M Kockx, Umut Akinci, Zeliha Ozgur, Marti Quevedo, Jeroen Demmers
Publikováno v:
Translational Psychiatry
Translational Psychiatry, 7:e1082. Nature Publishing Group
Translational Psychiatry, 7:e1082. Nature Publishing Group
Mental disorders (MDs) such as intellectual disability (ID), autism spectrum disorders (ASD) and schizophrenia have a strong genetic component. Recently, many gene mutations associated with ID, ASD or schizophrenia have been identified by high-throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d33783c7404232c7ec70337a340694a
https://doi.org/10.1038/tp.2017.52
https://doi.org/10.1038/tp.2017.52
Autor:
Jeroen Demmers, Shoumo Bhattacharya, Maaike J. Moen, Frank Grosveld, Sjaak Philipsen, Dick H. W. Dekkers, Wilfred F. J. van IJcken, Dorota Szumska, Robbert J. Rottier, Jan Christian Bryne, Erikjan Rijkers, Boris Lenhard, Larysa H. Pevny, Raymond A. Poot, Christel E M Kockx, Cristina Gontan, Jun Hou, Erik Engelen, Umut Akinci
Publikováno v:
Nature Genetics, 43(6), 607-U153. Nature Publishing Group
The HMG-box transcription factor Sox2 plays a role throughout neurogenesis and also acts at other stages of development, as illustrated by the multiple organs affected in the anophthalmia syndrome caused by SOX2 mutations. Here we combined proteomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442e0f0621ef8b12d780b8575e00e140
https://doi.org/10.1038/ng.825
https://doi.org/10.1038/ng.825
Autor:
Frank Grosveld, Niels Galjart, Tatiana Stepanova, Jeffrey van Haren, Mieke Mommaas, Ronald W. A. L. Limpens, Umut Akinci, Marja Miedema, Michael I.J.A. van der Reijden, Erik Meijering, Raymond A. Poot, Zhe Liu, Ihor Smal, Marco van Ham
Publikováno v:
Current Biology, 20(11), 1023-1028
Current Biology, 20(11), 1023-1028. Cell Press
Current Biology, 20(11), 1023-1028. Cell Press
SummaryIn Chinese hamster ovary cells, microtubules originate at the microtubule organizing center (MTOC) and grow persistently toward the cell edge, where they undergo catastrophe [1]. In axons, microtubule dynamics must be regulated differently bec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2112117162c4a6afd1e51e996c7523eb
https://hdl.handle.net/1765/21175
https://hdl.handle.net/1765/21175
Autor:
Justin Goodrich, Daniel Schubert, Ueli Grossniklaus, Oliver Clarenz, Umut Akinci, Claudia Köhler, Olivier Leroy, Grigory Makarevich
Publikováno v:
EMBO reports. 7:947-952
Polycomb group (PcG) proteins convey epigenetic inheritance of repressed transcriptional states. Although the mechanism of the action of PcG is not completely understood, methylation of histone H3 lysine 27 (H3K27) is important in establishing PcG-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467ce3d974dbb0c3a319c2ff7fd27680
https://doi.org/10.1038/sj.embor.7400760
https://doi.org/10.1038/sj.embor.7400760
Autor:
Tatjana Nikolic, Joseph E. Italiano, Jean-Charles Boisset, Jeffrey van Haren, Mieke Mommaas, Zhe Liu, Wilfred F. J. van IJcken, Sunita R. Patel, Niels Galjart, Thomas Clapes, Dubravka Drabek, Rudi W. Hendriks, Marcel Vermeij, Sjaak Philipsen, Ana L. Pereira, Catherine Robin, Clara Melo, Helder Maiato, Marjolein Meinders, Mirjam C G N van den Hout, Ksenija Drabek, Umut Akinci, Frank Grosveld, Clara Sambade, Laura Gutierrez
Publikováno v:
Cell reports, 2(4), 781-788. Cell Press
Cell Reports, 2(4), 781-788
Cell Reports
Cell Reports, Vol 2, Iss 4, Pp 781-788 (2012)
Cell Reports, 2(4), 781-788. Cell Press
Cell Reports, 2(4), 781-788
Cell Reports
Cell Reports, Vol 2, Iss 4, Pp 781-788 (2012)
Cell Reports, 2(4), 781-788. Cell Press
Mammalian CLASPs are microtubule plus-end tracking proteins whose essential function as regulators of microtubule behavior has been studied mainly in cultured cells. We show here that absence of murine CLASP2 in vivo results in thrombocytopenia, prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7560b48c2d6156b1a21287c684bb14a8
https://pubmed.ncbi.nlm.nih.gov/23084744
https://pubmed.ncbi.nlm.nih.gov/23084744