Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Umme, Kolsum"'
Autor:
Anna Esteve-Codina, Thomas P. Hofer, Dorothe Burggraf, Marion S. Heiss-Neumann, Wolfgang Gesierich, Anne Boland, Robert Olaso, Marie-Therese Bihoreau, Jean-Francois Deleuze, Winfried Moeller, Otmar Schmid, María Soler Artigas, Kathrin Renner, Jens M. Hohlfeld, Tobias Welte, Thomas Fuehner, Lukas Jerrentrup, Andreas Rembert Koczulla, Timm Greulich, Antje Prasse, Joachim Müller-Quernheim, Sumit Gupta, Christopher Brightling, Deepak R. Subramanian, David G. Parr, Umme Kolsum, Vandana Gupta, Imre Barta, Balázs Döme, János Strausz, Mariarita Stendardo, Marco Piattella, Piera Boschetto, Damian Korzybski, Dorota Gorecka, Adam Nowinski, Marc Dabad, Marcos Fernández-Callejo, David Endesfelder, Wolfgang zu Castell, Pieter S. Hiemstra, Per Venge, Elfriede Noessner, Thasso Griebel, Simon Heath, Dave Singh, Ivo Gut, Loems Ziegler-Heitbrock
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Chronic obstructive pulmonary disease (COPD) is a destructive inflammatory disease and the genes expressed within the lung are crucial to its pathophysiology. We have determined the RNAseq transcriptome of bronchial brush cells from 312 stri
Externí odkaz:
https://doaj.org/article/910271cd28a0431e890028bbd9684f22
Autor:
Augusta S. Beech, Simon Lea, Umme Kolsum, Zhang Wang, Bruce E. Miller, Gavin C. Donaldson, Jadwiga A. Wedzicha, Christopher E. Brightling, Dave Singh
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-13 (2020)
Abstract Background There is evidence that bacterial colonisation in chronic obstructive pulmonary disease (COPD) is associated with increased neutrophilic airway inflammation. This study tested the hypothesis that different bacterial phyla and speci
Externí odkaz:
https://doaj.org/article/5a2293924db94ec4a0b39990a3eb85c8
Autor:
Gabriella H. Long, Thomas Southworth, Umme Kolsum, Gavin C. Donaldson, Jadwiga A. Wedzicha, Christopher E. Brightling, Dave Singh
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-4 (2020)
Abstract Blood eosinophils are a predictive biomarker of inhaled corticosteroid response in chronic obstructive pulmonary disease (COPD). We investigated blood eosinophil stability over 1 year using the Global Initiative for Chronic Obstructive Lung
Externí odkaz:
https://doaj.org/article/b5e9c1d4054b478582f71907727e45ed
Autor:
Zhang Wang, Barbara Maschera, Simon Lea, Umme Kolsum, David Michalovich, Stephanie Van Horn, Christopher Traini, James R. Brown, Edith M. Hessel, Dave Singh
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-14 (2019)
Abstract Background Little is known about the interactions between the lung microbiome and host response in chronic obstructive pulmonary disease (COPD). Methods We performed a longitudinal 16S ribosomal RNA gene-based microbiome survey on 101 sputum
Externí odkaz:
https://doaj.org/article/c51a6388ea8f42bebea01184343a0bf7
Autor:
Umme Kolsum, Gavin C. Donaldson, Richa Singh, Bethan L. Barker, Vandana Gupta, Leena George, Adam J. Webb, Sarah Thurston, Anthony J Brookes, Timothy D. McHugh, Jadwiga A. Wedzicha, Christopher E. Brightling, Dave Singh
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-11 (2017)
Abstract Background Sputum and blood eosinophil counts predict corticosteroid effects in COPD patients. Bacterial infection causes increased airway neutrophilic inflammation. The relationship of eosinophil counts with airway bacterial load in COPD pa
Externí odkaz:
https://doaj.org/article/fd54ce860ca34c0fac71466a6ab5a358
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-7 (2017)
Abstract Eosinophilic COPD appears to be a distinct patient subgroup with an increased corticosteroid response. Eosinophilic COPD has been labelled as part of the asthma COPD overlap syndrome (ACOS). We compared the clinical characteristics of eosino
Externí odkaz:
https://doaj.org/article/87ded3da0fe141e3bcd7cf71b5d9bc82
Autor:
Andrew Higham, Paul Cadden, Thomas Southworth, Matthew Rossall, Umme Kolsum, Simon Lea, Richard Knowles, Dave Singh
Publikováno v:
ERJ Open Research, Vol 2, Iss 4 (2016)
Poor asthma control is associated with increased airway neutrophils. Leukotriene B4 (LTB4) is a potent neutrophil chemoattractant. We examined the levels of LTB4 levels in the sputum of asthma patients and the relationship with disease severity. 47 a
Externí odkaz:
https://doaj.org/article/a8336b78597146d3bd29d197bc8398c4
Autor:
Francesc Castro-Giner, Dave Singh, Antje Prasse, Joachim Müller-Quernheim, David G. Parr, Piera Boschetto, Lidia Agueda, Sophia Derdak, Jean-François Deleuze, Katherine Apunte-Ramos, Loems Ziegler-Heitbrock, Marta Gut, Gian-Andri Thun, Mariarita Stendardo, Matthias Wjst, Timm Greulich, Adam Nowinski, Marion S Heiss-Neumann, Dorota Górecka, Anne Boland, Ivo Gut, Tobias Welte, Imre Barta, Jens M. Hohlfeld, Umme Kolsum, Balazs Dome, Christopher E. Brightling
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Sci. Rep. 9:20158 (2019)
Scientific Reports
Sci. Rep. 9:20158 (2019)
Chronic obstructive pulmonary disease (COPD) is induced by cigarette smoking and characterized by inflammation of airway tissue. Since smokers with COPD have a higher risk of developing lung cancer than those without, we hypothesized that they carry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0434b1ec6209676ffa3794a1778de7b4
http://link.springer.com/article/10.1038/s41598-019-56618-1
http://link.springer.com/article/10.1038/s41598-019-56618-1
Publikováno v:
International Journal of COPD, Vol 2009, Iss default, Pp 149-156 (2009)
Umme Kolsum, Kay Roy, Cerys Starkey, Zoë Borrill, Nick Truman, Jørgen Vestbo, Dave SinghNorth West Lung Research Centre, University of Manchester, South Manchester University Hospitals Trust, Wythenshawe, Manchester, UKBackground: Many of the syste
Externí odkaz:
https://doaj.org/article/166eb68913a04d7fba857a8830d28119
Autor:
Timm Greulich, Simon Heath, Wolfgang Gesierich, Winfried Moeller, David Endesfelder, María Soler Artigas, Thasso Griebel, Andreas Rembert Koczulla, Anna Esteve-Codina, Jens M. Hohlfeld, Umme Kolsum, Robert Olaso, Balazs Dome, Ivo Gut, Mariarita Stendardo, Tobias Welte, János Strausz, Christopher E. Brightling, Deepak Subramanian, Marcos Fernandez-Callejo, Marion S Heiss-Neumann, Antje Prasse, Sunil Gupta, Marie-Thérèse Bihoreau, Dorothe Burggraf, Dave Singh, Marc Dabad, Piera Boschetto, Jean-François Deleuze, Imre Barta, Damian Korzybski, Joachim Müller-Quernheim, Per Venge, Thomas Fuehner, Kathrin Renner, Pieter S. Hiemstra, Loems Ziegler-Heitbrock, Thomas Höfer, Lukas Jerrentrup, Marco Piattella, Otmar Schmid, David G. Parr, Dorota Górecka, Elfriede Noessner, Wolfgang zu Castell, Anne Boland, Adam Nowinski, Vandana Gupta
Publikováno v:
Scientific Reports, 11(1). NATURE RESEARCH
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Sci. Rep. 11:12848 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Sci. Rep. 11:12848 (2021)
Chronic obstructive pulmonary disease (COPD) is a destructive inflammatory disease and the genes expressed within the lung are crucial to its pathophysiology. We have determined the RNAseq transcriptome of bronchial brush cells from 312 stringently d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05121efdd94f77fc1a5a22d10288ed59
http://hdl.handle.net/1887/3238102
http://hdl.handle.net/1887/3238102
