Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Umji Choi"'
Publikováno v:
mSystems, Vol 9, Iss 10 (2024)
ABSTRACT Tetracyclines and glycylcycline are among the important antibiotics used to combat infections caused by multidrug-resistant Gram-negative pathogens. Despite the clinical importance of these antibiotics, their mechanisms of resistance remain
Externí odkaz:
https://doaj.org/article/9957d67a5cd0446889f4228848cfe79c
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Peptidoglycan (PG) is an essential bacterial architecture pivotal for shape maintenance and adaptation to osmotic stress. Although PG synthesis and modification are tightly regulated under harsh environmental stresses, few related mechanisms
Externí odkaz:
https://doaj.org/article/588585861526483398156a0b43d7f06f
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT Vancomycin and β-lactams are clinically important antibiotics that inhibit the formation of peptidoglycan cross-links, but their binding targets are different. The binding target of vancomycin is d-alanine-d-alanine (d-Ala-d-Ala), whereas t
Externí odkaz:
https://doaj.org/article/c81fbf3ec16b419185c2f1532661c818
Publikováno v:
Molecules, Vol 28, Iss 8, p 3638 (2023)
Pyrrole-ligated 1,3,4-oxadiazole is a very important pharmacophore which exhibits broad therapeutic effects such as anti-tuberculosis, anti-epileptic, anti-HIV, anti-cancer, anti-inflammatory, antioxidant, and antibacterial activities. A one-pot Mail
Externí odkaz:
https://doaj.org/article/8f40886919a74624b9f2da512112bcd6
Autor:
Yung Jae Kim, Byoung Jun Choi, Si Hyoung Park, Han Byeol Lee, Ji Eun Son, Umji Choi, Won-Jae Chi, Chang-Ro Lee
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Peptidoglycan (PG) hydrolases play important roles in various aspects of bacterial physiology, including cytokinesis, PG synthesis, quality control of PG, PG recycling, and antibiotic resistance. However, the regulatory mechanisms of their expression
Externí odkaz:
https://doaj.org/article/5caf73bc31c34b53bce75c132c6b2b53
Autor:
Umji Choi, Chang-Ro Lee
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
A defining characteristic of Gram-negative bacteria is the presence of an outer membrane, which functions as an additional barrier inhibiting the penetration of toxic chemicals, such as antibiotics. Porins are outer membrane proteins associated with
Externí odkaz:
https://doaj.org/article/70e4659a41164228bff5ee22eb5eb17f
Peptidoglycan (PG) is an essential bacterial architecture pivotal for shape maintenance and adaptation to osmotic stress. Although PG synthesis and modification are tightly regulated under harsh environmental stresses, few related mechanisms have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d6e3b89d0b945f71d3387df172b77a5
https://doi.org/10.1101/2022.09.06.506770
https://doi.org/10.1101/2022.09.06.506770
Vancomycin and β-lactams are clinically important antibiotics that inhibit the formation of peptidoglycan cross-links, but their binding targets are different. The binding target of vancomycin is D-alanine-D-alanine (D-Ala-D-Ala), whereas that of β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fab766609e30e599262dccfa0570c62
https://doi.org/10.1101/2022.04.04.487088
https://doi.org/10.1101/2022.04.04.487088
Autor:
Sangho Koo, Umji Choi, Hui Jin, Chang-Ro Lee, Chul Gi Sung, Haiyang Yu, Xia Jiang, Hyebin Yoo, Tingshu Wang
Publikováno v:
ChemistrySelect. 5:12421-12424
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc7cd85eb1ee4cc6364b27cb1a435769
https://doi.org/10.1002/slct.202003397
https://doi.org/10.1002/slct.202003397
Publikováno v:
Journal of Microbiology. 58:598-605
Although bacteria have diverse membrane proteins, the function of many of them remains unknown or uncertain even in Escherichia coli. In this study, to investigate the function of hypothetical membrane proteins, genome-wide analysis of phenotypes of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c59b6c8291909b92d2406a2d0e2885
https://doi.org/10.1007/s12275-020-0078-4
https://doi.org/10.1007/s12275-020-0078-4