P53 and VEGF are promising biomarkers for sorafenib efficacy in an experimental model of NASH-related HCC.

Autor: Nassar-Reis JP; Laboratory of Experimental and Comparative Liver Research (Liver Lab), Department of Pathology, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, 05508-270, Brazil.; Laboratório de Gastroenterologia Clínica e Experimental (LIM-07), Division of Clinical Gastroenterology and Hepatology, Department of Gastroenterology, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, 01246-903, Brazil., Umeta PF; Laboratório de Gastroenterologia Clínica e Experimental (LIM-07), Division of Clinical Gastroenterology and Hepatology, Department of Gastroenterology, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, 01246-903, Brazil., Stefano JT; Laboratório de Gastroenterologia Clínica e Experimental (LIM-07), Division of Clinical Gastroenterology and Hepatology, Department of Gastroenterology, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, 01246-903, Brazil., Longatto-Filho A; Department of Pathology (LIM-14), University of São Paulo School of Medicine, São Paulo, 05808-010, Brazil.; School of Medicine, Life and Health Sciences Research Institute (ICVS), University of Minho, 4704-553, Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, 4710-057, Braga, Portugal.; Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, 14784-400, Brazil., Carrilho FJ; Laboratório de Gastroenterologia Clínica e Experimental (LIM-07), Division of Clinical Gastroenterology and Hepatology, Department of Gastroenterology, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, 01246-903, Brazil., Alves VAF; Department of Pathology (LIM-14), University of São Paulo School of Medicine, São Paulo, 05808-010, Brazil., Cogliati B; Laboratory of Experimental and Comparative Liver Research (Liver Lab), Department of Pathology, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, 05508-270, Brazil., Oliveira CP; Laboratório de Gastroenterologia Clínica e Experimental (LIM-07), Division of Clinical Gastroenterology and Hepatology, Department of Gastroenterology, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, 01246-903, Brazil. cpm@usp.br.

Publikováno v: Journal of molecular histology [J Mol Histol] 2023 Oct; Vol. 54 (5), pp. 473-488. Date of Electronic Publication: 2023 Aug 21.