Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Umesh B. Mahajan"'
Autor:
Milind V. Masule, Sumit Rathod, Yogeeta Agrawal, Chandragouda R. Patil, Kartik T. Nakhate, Shreesh Ojha, Sameer N. Goyal, Umesh B. Mahajan
Publikováno v:
Current Research in Pharmacology and Drug Discovery, Vol 3, Iss , Pp 100113- (2022)
Ghrelin is a peptide released by the endocrine cells of the stomach and the neurons in the arcuate nucleus of the hypothalamus. It modulates both peripheral and central functions. Although ghrelin has emerged as a potent stimulator of growth hormone
Externí odkaz:
https://doaj.org/article/4c03a5d41634424195dbd976cc8f6d96
Autor:
Ashwani S. Patil, Umesh B. Mahajan, Yogeeta O. Agrawal, Kalpesh R. Patil, Chandragouda R. Patil, Shreesh Ojha, Charu Sharma, Sameer N. Goyal
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 132, Iss , Pp 110889- (2020)
The endocannabinoid system (ECS) is natural physiological system in the humans. The presence of the ECS system involves different roles in body. The endocannabinoid system involves regulation of most of the centers, which regulates the hunger and lea
Externí odkaz:
https://doaj.org/article/ff9ef893f7724518b7e4bd510b8543d5
Autor:
Harshal D. Pawar, Umesh B. Mahajan, Kartik T. Nakhate, Yogeeta O. Agrawal, Chandragouda R. Patil, M. F. Nagoor Meeran, Charu Sharma, Shreesh Ojha, Sameer N. Goyal
Publikováno v:
Life, Vol 12, Iss 5, p 624 (2022)
Molecular docking revealed curcumin as a potent CB2 cannabinoid receptor (CB2R) agonist. Since CB2R is involved in cardioprotective functions, we explored its role in ameliorative actions of curcumin against myocardial damage triggered by isoproteren
Externí odkaz:
https://doaj.org/article/f392285729e74debb7d574bc30827784
Autor:
Yogeeta O. Agrawal, Umesh B. Mahajan, Vinit V. Agnihotri, Mayur S. Nilange, Hitendra S. Mahajan, Charu Sharma, Shreesh Ojha, Chandragouda R. Patil, Sameer N. Goyal
Publikováno v:
Molecules, Vol 26, Iss 5, p 1485 (2021)
Ezetimibe (EZE) possesses low aqueous solubility and poor bioavailability and in addition, its extensive hepatic metabolism supports the notion of developing a novel carrier system for EZE. Ezetimibe was encapsulated into nanostructured lipid carrier
Externí odkaz:
https://doaj.org/article/89813777aefa44b684ea8ef442bbdda0
Autor:
Sameer N. Goyal, Chaitali P. Prajapati, Prashant R. Gore, Chandragouda R. Patil, Umesh B. Mahajan, Charu Sharma, Sandhya P. Talla, Shreesh K. Ojha
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Thymoquinone, a monoterpene molecule is chemically known as 2-methyl-5-isopropyl-1, 4-benzoquinone. It is abundantly present in seeds of Nigella sativa L. that is popularly known as black cumin or black seed and belongs to the family Ranunculaceae. A
Externí odkaz:
https://doaj.org/article/e0f951d7fd5c42889f95363c33086f75
Autor:
Shreesh Ojha, Sateesh Belemkar, Avinash R Wadkar, Lalit A Birari, Sanjay J. Surana, Umesh B Mahajan, Chandragouda R. Patil, Kalpesh R. Patil, Sameer N. Goyal, Aarti S Kale
Publikováno v:
Asian Pacific Journal of Tropical Biomedicine, Vol 11, Iss 5, Pp 205-213 (2021)
Objective: To investigate the effect of aloin against chronic constriction injury (CCI)-induced neuropathic pain in rats. Methods: Rats were randomly divided into 7 groups: Group I (normal control), Group II (sham-operated), Group III (CCI control) a
Publikováno v:
International Journal of Pharmaceutical Sciences and Drug Research. :181-189
Barringtonia racemosa (B. racemosa) is a tropical medicinal plant possessing interesting biological activities. B. racemosa fruits are traditionally used in India for the treatment of pain, inflammation, and rheumatic conditions. Earlier, we have rep
Autor:
Chaitali Prajapati, Yogeeta O. Agrawal, Vinit V. Agnihotri, Umesh B. Mahajan, Kalpesh R. Patil, Dipak D. Patil, Chandragouda R. Patil
Publikováno v:
International journal of biological macromolecules. 214
Thymoquinone (TQ), the most prominent constituent of Nigella sativa seeds, essential oil, is reported to possess an organ protective effect via Nrf2 expression and activation of Phase-II antioxidant enzymes. Haemorrhagic cystitis is the sudden onset
Autor:
Kalpesh R. Patil, Umesh B Mahajan, Sameer N. Goyal, Chandragouda R. Patil, Harun M. Patel, Shraddha I Khairnar, Sachin D. Shinde, Shreesh Ojha, Sateesh Belemkar
Publikováno v:
Biological Trace Element Research. 193:174-184
The use of cisplatin (CP) in chemotherapy of resistant cancers is limited due to its dose-dependent nephrotoxicity. Disulfiram (DSF), the aversion therapy for alcoholism, has recently emerged as an anticancer and chemopreventive agent. Its anticancer
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 392:659-668
Ferulic acid (FA) is a phenolic compound with potent antioxidant activity. The objective of the study was to study the protective effects of FA on doxorubicin (Dox)-induced myocardial toxicity in rats. Wistar rats received vehicle (control) or Dox (2