Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Umesh B. Gangadharmath"'
Autor:
Helen Su, Umesh B. Gangadharmath, Joseph C. Walsh, Natalia Gorodny, Fanrong Mu, Gang Chen, Balaji Tamarappoo, Daniel S. Berman, Hartmuth C. Kolb, Luis F. Gomez, Katrin Szardenings
Publikováno v:
Journal of Nuclear Cardiology. 21:553-562
Rupture of unstable atherosclerotic plaque that leads to stroke and myocardial infarction may be induced by macrophage infiltration and neovessel formation. A tracer that selectively binds to integrin αvβ3 a protein expressed by macrophages and neo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac62ecef6152864c8da907f26fb01fcb
https://doi.org/10.1007/s12350-014-9879-3
https://doi.org/10.1007/s12350-014-9879-3
Autor:
Qianwa Liang, Fanrong Mu, Hartmuth C. Kolb, Gang Chen, A. Katrin Szardenings, Luis F. Gomez, Helen Su, Chunfang Xia, Vani P. Mocharla, Joseph C. Walsh, Tieming Zhao, Umesh B. Gangadharmath
Publikováno v:
Molecular Imaging and Biology. 15:748-757
A novel caspase-3 substrate-based probe [(18)F]-CP18 was evaluated as an in vivo positron emission tomography (PET) imaging agent for monitoring apoptosis in tumors.Uptake of [(18)F]-CP18 in cell assays and tumors was measured. Caspase-3/7 activities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e606848960785487621d2ccdb98044
https://doi.org/10.1007/s11307-013-0646-7
https://doi.org/10.1007/s11307-013-0646-7
Autor:
Qianwa Liang, Luis F. Gomez, Joseph C. Walsh, Hartmuth C. Kolb, Fanrong Mu, A. Katrin Szardenings, Helen Su, Chunfang Xia, Gang Chen, Vani P. Mocharla, Umesh B. Gangadharmath, Chul Yu
Publikováno v:
Molecular Imaging and Biology. 15:739-747
We identified and validated [18F]-CP18, a DEVD (the caspase 3 substrate recognition motif) containing substrate-based compound as an imaging tracer for caspase-3 activity in apoptotic cells. CP18 was radiolabeled with fluorine-18 using click chemistr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bcc5cff99ec4ce939a1db50be39b2e1
https://doi.org/10.1007/s11307-013-0644-9
https://doi.org/10.1007/s11307-013-0644-9
Autor:
Janna Arteaga, Chung Lam, Eric Wang, Umesh B. Gangadharmath, Daniel Kurt Cashion, Fanrong Mu, Joseph C. Walsh, Luis F. Gomez, Chul Yu, Tieming Zhao, Hartmuth C. Kolb, A. Katrin Szardenings, Dhanalakshmi Kasi, Qianwa Liang, Changhui Liu, Chunfang Xia, Anjana Sinha, Vani P. Mocharla, Wei Zhang, Gang Chen
Publikováno v:
Journal of Alzheimer's Disease. 31:601-612
Senile plaques and neurofibrillary tangles are prominent neuropathological hallmarks in Alzheimer's disease and are considered to be targets for therapeutic intervention as well as biomarkers for diagnostic in vivo imaging agents. While there are a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e708724e3f611e274fe7d2227e0f57af
https://doi.org/10.3233/jad-2012-120712
https://doi.org/10.3233/jad-2012-120712
Autor:
Fabian Galla, Artem Y. Lebedev, Vani P. Mocharla, Stefan Wagner, Umesh B. Gangadharmath, Hartmuth C. Kolb, Katrin Szardenings, Sven Hermann, Klaus Kopka, Bernhard Wünsch, Verena Hugenberg, Joseph C. Walsh, Michael Schäfers
Publikováno v:
Nuclear medicine and biology. 43(7)
Introduction Dysregulated MMP expression or activation is associated with several diseases. To study MMP activity in vivo by means of PET a radiolabeled MMP inhibitor (MMPI) functioning as radiotracer has been developed by our group based on the lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5a3b27f1f17ee96b8ef4d975c66666
https://pubmed.ncbi.nlm.nih.gov/27179748
https://pubmed.ncbi.nlm.nih.gov/27179748
Autor:
Natalia Gorodny, Fanrong Mu, Joseph C. Walsh, Balaji Tamarappoo, Hartmuth C. Kolb, Gang Chen, Umesh B. Gangadharmath, Helen Su, Luis F. Gomez, Katrin Szardenings
Publikováno v:
Circulation: Cardiovascular Imaging. 8
Background— Anthracycline-induced cardiotoxicity and myocardial dysfunction may be associated with apoptosis. Caspase 3 catalyzes a terminal step in apoptosis, and its expression may serve as a marker of cardiomyocyte apoptosis. We synthesized 18F-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d931124bfd4313aeb06dfdd907ea9e98
https://doi.org/10.1161/circimaging.114.001952
https://doi.org/10.1161/circimaging.114.001952
Autor:
Satish M. Annigeri, Umesh B Gangadharmath, Anil D Naik, Vidyanand K. Revankar, Vijaykumar Reddy, Vinayak B. Mahale
Publikováno v:
Bulletin of the Chemical Society of Japan. 75:2161-2167
The preparation of a novel pentadentate binucleating compartmental ligand, 2-hydroxy-5-methylisophthalaldehyde bis(p-methoxy thiobenzoylhydrazone), is described together with the corresponding chloro-bridged cobalt(II), nickel(II), copper(II) and zin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b15e582f015f68626c34e734f75ebc3a
https://doi.org/10.1246/bcsj.75.2161
https://doi.org/10.1246/bcsj.75.2161
Autor:
Satish M. Annigeri, Vidyanand K. Revankar, Vinayak B. Mahale, Anil D Naik, Umesh B Gangadharmath
Publikováno v:
Journal of Molecular Structure. 616:119-127
2,6-Diformyl-p-cresol serves as a starting point for the generation of multidentate N/O/S chelating agents. Condensation with 4-(X-phenyl) thiosemicarbazide yields the pentadentate ligand having SNONS donor sequences, capable of holding two metal ion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8896566d937ac8d2614220095861cdac
https://doi.org/10.1016/s0022-2860(02)00313-7
https://doi.org/10.1016/s0022-2860(02)00313-7
Autor:
Satish M. Annigeri, Umesh B Gangadharmath, Vidyanand K. Revankar, Vinayak B. Mahale, Anil D Naik
Publikováno v:
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 58:1713-1719
A new binucleating ligand containing phenoxide as an endogenous bridging group, 2,6-diformyl-p-cresol bis(2-furanthiocarboxyhydrazone) and its binuclear Co(II), Ni(II), Cu(II) and Zn(II) complexes with chloride ion as an exogenous bridge, have been o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360d179761c72c8417c1a677baba3402
https://doi.org/10.1016/s1386-1425(01)00624-2
https://doi.org/10.1016/s1386-1425(01)00624-2
Autor:
Vidyanand K. Revankar, Vinayak B. Mahale, Anil D Naik, Umesh B Gangadharmath, Satish M. Annigeri
Publikováno v:
Journal of Inclusion Phenomena and Macrocyclic Chemistry. 43:291-297
New dinuclear complexes of macrocycles/macroacycles/oximeshaving a reactive peripheral thioketo functional group were synthesized using2,6-diformyl-p-cresol as parent compound and thiocarbohydrazide/variousdiamines as side arms. Thioenolization and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85025ab8458ba0f916da1c8812b4616c
https://doi.org/10.1023/a:1021289104845
https://doi.org/10.1023/a:1021289104845