Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Umesh, Khaniya"'
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Biological membranes are barriers to polar molecules, so membrane embedded proteins control the transfers between cellular compartments. Protein controlled transport moves substrates and activates cellular signaling cascades. In addition, the electro
Externí odkaz:
https://doaj.org/article/59faad757d5c43bb9630b069cc80a9b4
Publikováno v:
The Journal of Physical Chemistry B. 126:2476-2485
Proteins are polyelectrolytes with acidic or basic amino acids making up ≈25% of the residues. The protonation state of all Asp, Glu, Arg, Lys, His and other protonatable residues, cofactors and ligands define each protonation microstate. As all of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e5d6b51094e2a76a5170c23fd7fec5e
https://doi.org/10.1021/acs.jpcb.2c00139
https://doi.org/10.1021/acs.jpcb.2c00139
Publikováno v:
Photosynthesis Research. 152:153-165
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d09d49a16b319b6e6fef3e8951ba819
https://doi.org/10.1007/s11120-022-00906-x
https://doi.org/10.1007/s11120-022-00906-x
Publikováno v:
Photosynthesis research.
Protons participate in many reactions. In proteins, protons need paths to move in and out of buried active sites. The vectorial movement of protons coupled to electron transfer reactions establishes the transmembrane electrochemical gradient used for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a55fd31a9e3e5452f84b8bf1d5a4287
https://pubmed.ncbi.nlm.nih.gov/36307598
https://pubmed.ncbi.nlm.nih.gov/36307598
Autor:
Divya Kaur, Xiuhong Cai, Umesh Khaniya, Yingying Zhang, Junjun Mao, Manoj Mandal, Marilyn R. Gunner
Publikováno v:
Inorganics, Vol 7, Iss 2, p 14 (2019)
Photosystem II (PSII) uses water as the terminal electron donor, producing oxygen in the Mn4CaO5 oxygen evolving complex (OEC), while cytochrome c oxidase (CcO) reduces O2 to water in its heme⁻Cu binuclear center (BNC). Each protein is oriented in
Externí odkaz:
https://doaj.org/article/d840a219f8b64dffab28c62fe7b0006a
Autor:
Marilyn R. Gunner, Xiuhong Cai, Divya Kaur, Kamran Haider, Sergei Y. Noskov, Umesh Khaniya, Junjun Mao, Xuyu Zhu, Van A. Ngo, Yingying Zhang, Themis Lazaridis
Publikováno v:
Journal of Computational Biophysics and Chemistry. 20:111-130
Water molecules play a key role in all biochemical processes. They help define the shape of proteins, and they are reactant or product in many reactions and are released as ligands are bound. They facilitate the transfer of protons through transmembr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10822ea5825a42c8bb0abbd82aff7ec6
https://doi.org/10.1142/s2737416520420016
https://doi.org/10.1142/s2737416520420016
Autor:
Marilyn R. Gunner, Abhishek Singharoy, Chitrak Gupta, Umesh Khaniya, François Dehez, Christophe Chipot, Mrinal Shekhar, Chun Kit Chan, Leonid A. Sazanov
Publikováno v:
Journal of the American Chemical Society
Journal of the American Chemical Society, American Chemical Society, 2020, 142 (20), pp.9220-9230. ⟨10.1021/jacs.9b13450⟩
Journal of the American Chemical Society, American Chemical Society, 2020, 142 (20), pp.9220-9230. ⟨10.1021/jacs.9b13450⟩
The mitochondrial respiratory chain, formed by five protein complexes, utilizes energy from catabolic processes to synthesize ATP. Complex I, the first and the largest protein complex of the chain, harvests electrons from NADH to reduce quinone, whil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba359b4c1f876a8c92faea9702892bc
https://doi.org/10.1021/jacs.9b13450
https://doi.org/10.1021/jacs.9b13450
Publikováno v:
Photosynthesis research. 152(2)
The photosynthetic bacterial reaction centers from purple non-sulfur bacteria use light energy to drive the transfer of electrons from cytochrome c to ubiquinone. Ubiquinone bound in the Q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ad734e327ca03dab11f4ffdb539b6e0f
https://pubmed.ncbi.nlm.nih.gov/35344134
https://pubmed.ncbi.nlm.nih.gov/35344134
Autor:
Chitrak, Gupta, Umesh, Khaniya, John W, Vant, Mrinal, Shekhar, Junjun, Mao, M R, Gunner, Abhishek, Singharoy
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2315
pH conditions are central to the functioning of all biomolecules. However, implications of pH changes are nontrivial on a molecular scale. Though a rigorous microscopic definition of pH exists, its implementation in classical molecular dynamics (MD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c0efd8e816946af0cbe30fd9b34fc9c1
https://pubmed.ncbi.nlm.nih.gov/34302678
https://pubmed.ncbi.nlm.nih.gov/34302678
Autor:
Marilyn R. Gunner, Junjun Mao, Divya Kaur, Victor S. Batista, Mikhail Askerka, Gary W. Brudvig, Krystle Reiss, Umesh Khaniya, Yingying Zhang, Witold Szejgis, Xiuhong Cai, Muhamed Amin
Publikováno v:
Photosynthesis Research, 141(3), 331-341. SPRINGER
The oxidation of water to O-2 is catalyzed by the Oxygen Evolving Complex (OEC), a Mn4CaO5 complex in Photosystem II (PSII). The OEC is sequentially oxidized from state S-0 to S-4. The S-2 state, (Mn-III)(Mn-IV)(3), coexists in two redox isomers: S-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0001d15763b234497dcdd83e858dd2ab
https://hdl.handle.net/11370/747dc65c-ddca-4aeb-8a0e-cd300d5fb55d
https://hdl.handle.net/11370/747dc65c-ddca-4aeb-8a0e-cd300d5fb55d