Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Umeko Semba"'
Publikováno v:
Pathology International. 64:543-550
Sera of human, guinea pig or mouse contain a strong monocyte chemoattractant capacity that is attributed to the ribosomal protein S19 (RP S19) oligomers generated during blood coagulation. In contrast, sera prepared from Gln137Glu-RP S19 gene knock-i
Autor:
Jun Chen, Tetsuro Yamamoto, Umeko Semba, Masato Oda, Shinichiro Hattori, Seiji Okada, Rui Zhao, Tomoyasu Suzuki, Ken Toba
Publikováno v:
Experimental and Molecular Pathology. 95:364-375
We performed a series of experiments under a working hypothesis that cross-linked oligomers of ribosomal protein S19 (RP S19) play an essential role in definitive erythropoiesis as a ligand of the C5a receptor of erythroblasts and macrophages. We fou
Autor:
Jun Chen, Umeko Semba, Tetsuro Yamamoto, Hiroshi Nishiura, Rui Zhao, Peiyu Xie, Akihiko Kuniyasu
Publikováno v:
International Immunopharmacology. 12:158-168
A recombinant complement anaphylatoxin, C4a, inhibited chemotaxis, respiratory burst and histamine release in mast cell-like HMC-1 cells that were treated with recombinant C5a anaphylatoxin. C4a also inhibited histamine release from HMC-1 cells that
Autor:
Kenichi Tsujita, Hiroshi Nishiura, Umeko Semba, Sumio Tanase, Hisao Ogawa, Seigo Sugiyama, Tetsuro Yamamoto, Tomohiro Nakagaki
Publikováno v:
European Journal of Haematology. 86:436-441
We have demonstrated that the cross-linking of ribosomal protein S19 (RP S19) on platelets by activated factor XIII provides chemotactic potency to monocytes/macrophages for a resolution of coagulum. Factor XIII is activated by an active form of prot
Autor:
Hiroshi Nishiura, Jun Chen, Yoshihiko Ota, Hirofumi Higuchi, Tetsuro Yamamoto, Umeko Semba, Toshihiro Nakashima
Publikováno v:
International Immunopharmacology. 10:1541-1547
The crosslinked homodimer of human ribosomal protein S19 (hRP S19) but not hRP S19 monomer shares the hC5a receptor ligation capacity with anaphylatoxin hC5a. The hRP S19 dimer engages hC5a receptor-bearing monocytes in chemotactic movement and secre
Autor:
Jun Chen, Hidetoshi Arima, Hiroshi Nishiura, Nan Jia, Yoshihiko Ota, Tetsuro Yamamoto, Umeko Semba
Publikováno v:
The American Journal of Pathology. 176:1542-1551
A monocyte-chemoattracting factor is generated during blood coagulation and during clotting of platelet-rich plasma. This chemotactic factor attracts monocytes as a ligand of the C5a receptor; however, it inhibits C5a-induced neutrophil chemotaxis as
Publikováno v:
Inflammation Research. 53:623-630
Objective: To reveal the C5a receptor-mediated monocyte-selective chemoattraction of the homo-dimer of guinea pig S19 ribosomal protein (RP S19), and to study the topological relationship between the RP S19 and C5a receptor genes. Methods: cDNA cloni
Publikováno v:
International Immunopharmacology. 4:1391-1400
Guinea pig high-molecular-weight and low-molecular-weight (HMW and LMW) kininogen cDNA were amplified from liver mRNA by RT-PCR. Their nucleotide sequences were analyzed and deduced to amino acid sequences. The HMW kininogen, composed of 607 amino ac
Autor:
Umeko Semba, Atsunobu Misumi, Hiroaki Okabe, Sebastião Mitsuji Miyazaki, Chizuko Nakamura, Akitoshi Murakami, Yoko Shibuya, Mimian Graciela Matsuda
Publikováno v:
Digestive Endoscopy. 15:35-42
Background: Phospholipids play an important role in gastric mucosal protection. The purpose of the present study was to investigate changes in various phospholipids in the fundic and pyloric gland mucosae of patients with gastric mucosal disease. Met
Publikováno v:
Pathology international. 64(11)
Sera of human, guinea pig or mouse contain a strong monocyte chemoattractant capacity that is attributed to the ribosomal protein S19 (RP S19) oligomers generated during blood coagulation. In contrast, sera prepared from Gln137Glu-RP S19 gene knock-i