Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Umberto di Porzio"'
Autor:
Salvatore Pulcrano, Roberto De Gregorio, Claudia De Sanctis, Laura Lahti, Carla Perrone-Capano, Donatella Ponti, Umberto di Porzio, Thomas Perlmann, Massimiliano Caiazzo, Floriana Volpicelli, Gian Carlo Bellenchi
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 6961 (2022)
The development of midbrain dopaminergic (DA) neurons requires a fine temporal and spatial regulation of a very specific gene expression program. Here, we report that during mouse brain development, the microRNA (miR-) 204/211 is present at a high le
Externí odkaz:
https://doaj.org/article/2e6e1d43887349c980e46c0a694c29c2
Autor:
Floriana Volpicelli, Roberto De Gregorio, Salvatore Pulcrano, Carla Perrone-Capano, Umberto di Porzio, Gian Carlo Bellenchi
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233918 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0030661.].
Externí odkaz:
https://doaj.org/article/24061e8bb8414fbeb8f525d6cba4d9ca
Autor:
Roberto De Gregorio, Salvatore Pulcrano, Claudia De Sanctis, Floriana Volpicelli, Ezia Guatteo, Lars von Oerthel, Emanuele Claudio Latagliata, Roberta Esposito, Rosa Maria Piscitelli, Carla Perrone-Capano, Valerio Costa, Dario Greco, Stefano Puglisi-Allegra, Marten P. Smidt, Umberto di Porzio, Massimiliano Caiazzo, Nicola Biagio Mercuri, Meng Li, Gian Carlo Bellenchi
Publikováno v:
Stem Cell Reports, Vol 10, Iss 4, Pp 1237-1250 (2018)
Summary: The differentiation of dopaminergic neurons requires concerted action of morphogens and transcription factors acting in a precise and well-defined time window. Very little is known about the potential role of microRNA in these events. By per
Externí odkaz:
https://doaj.org/article/3c07e32b8cbb4c9bbf1ce3db9c93dc16
Publikováno v:
Cells, Vol 10, Iss 4, p 735 (2021)
Dopamine (DA) is a key neurotransmitter involved in multiple physiological functions including motor control, modulation of affective and emotional states, reward mechanisms, reinforcement of behavior, and selected higher cognitive functions. Dysfunc
Externí odkaz:
https://doaj.org/article/a5c62ac7b3174dd6a641c2f3c169dee1
Autor:
Floriana Volpicelli, Carla Perrone-Capano, Gian Carlo Bellenchi, Luca Colucci-D’Amato, Umberto di Porzio
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 3995 (2020)
The relatively few dopaminergic neurons in the mammalian brain are mostly located in the midbrain and regulate many important neural functions, including motor integration, cognition, emotive behaviors and reward. Therefore, alteration of their funct
Externí odkaz:
https://doaj.org/article/67c904064ee34d9ea7de5825f288c942
Autor:
Floriana Volpicelli, Claudia Consales, Massimiliano Caiazzo, Luca Colucci-D'Amato, Carla Perrone-Capano, Umberto di Porzio
Publikováno v:
Neural Plasticity, Vol 11, Iss 1-2, Pp 45-57 (2004)
We analyzed the molecular mechanisms involved in the acquisition and maturation of dopaminergic (DA) neurons generated in vitro from rat ventral mesencephalon (MES) cells in the presence of mitogens or specific signaling molecules. The addition of ba
Externí odkaz:
https://doaj.org/article/8b2f11877a2d4fbda2629454b6dde78f
Autor:
Floriana Volpicelli, Massimiliano Caiazzo, Bruno Moncharmont, Umberto di Porzio, Luca Colucci-D'Amato
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109671 (2014)
Estrogens promote a plethora of effects in the CNS that profoundly affect both its development and mature functions and are able to influence proliferation, differentiation, survival and neurotransmission. The biological effects of estrogens are cell
Externí odkaz:
https://doaj.org/article/449cb7eb761e4fa4911c49e1f20cd237
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 4, Pp 581-589 (2001)
Abnormal neurofilament aggregates are pathological hall-mark of most neurodegenerative diseases, although their pathogenic role remains unclear. Increased expression of medium neurofilament (NFM) is an early molecular marker of wobbler mouse, an anim
Externí odkaz:
https://doaj.org/article/2456de0ebdb7479f95a4d2f503f22330
Autor:
Floriana Volpicelli, Roberto De Gregorio, Salvatore Pulcrano, Carla Perrone-Capano, Umberto di Porzio, Gian Carlo Bellenchi
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30661 (2012)
Due to their correlation with major human neurological diseases, dopaminergic neurons are some of the most studied neuronal subtypes. Mesencephalic dopaminergic (mDA) differentiation requires the activation of a cascade of transcription factors, amon
Externí odkaz:
https://doaj.org/article/9402b735a5dd41ce89c6284366b6aa2e
Autor:
Dario Greco, Floriana Volpicelli, Antonio Di Lieto, Damiana Leo, Carla Perrone-Capano, Petri Auvinen, Umberto di Porzio
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4977 (2009)
In the mammalian central nervous system (CNS) an important contingent of dopaminergic neurons are localized in the substantia nigra and in the ventral tegmental area of the ventral midbrain. They constitute an anatomically and functionally heterogene
Externí odkaz:
https://doaj.org/article/42563001c7a2464ea65be53120afc5f7