Zobrazeno 1 - 10
of 298
pro vyhledávání: '"Umberto Vespasiani"'
Autor:
Grazia Pennisi, Rosaria Maria Pipitone, Marco Enea, Antonio De Vincentis, Salvatore Battaglia, Vito Di Marco, Vincenzo Di Martino, Federica Spatola, Federica Tavaglione, Umberto Vespasiani‐Gentilucci, Rossella Zito, Stefano Romeo, Calogero Cammà, Antonio Craxì, Stefania Grimaudo, Salvatore Petta
Publikováno v:
Hepatology Communications, Vol 6, Iss 5, Pp 1032-1044 (2022)
Nonalcoholic fatty liver disease (NAFLD) is an emerging cause of liver‐related events (LREs). Here, we have assessed the ability of a composite score based on clinical features, metabolic comorbidities, and genetic variants to predict LREs. A total
Externí odkaz:
https://doaj.org/article/ca8d9c8c1ddc49cda262f32703207fe1
Autor:
Filippo Biagi, Francesco Carlomagno, Martina Carbone, Roberta Veralli, Umberto Vespasiani-Gentilucci, Elisabetta Riva, Silvia Manfrini, Dario Tuccinardi, Adriano De Santis, Lucio Gnessi, Mikiko Watanabe
Publikováno v:
Metabolites, Vol 13, Iss 11, p 1119 (2023)
Fibroblast growth factor 21 (FGF-21), previously recognized as a marker of liver damage and a potential drug target in non-alcoholic fatty liver disease (NAFLD), has unclear implications in hepatitis C virus (HCV) infections. This study aimed to inve
Externí odkaz:
https://doaj.org/article/8f4d3c38c1234e8587961683754eb9ad
Autor:
Simone Carotti, Daniele Lettieri-Barbato, Fiorella Piemonte, Sergio Ruggiero, Marco Rosina, Francesca Zalfa, Maria Zingariello, Francesca Arciprete, Francesco Valentini, Maria Francesconi, Jessica D’Amico, Antonio De Vincentis, Andrea Baiocchini, Giuseppe Perrone, Raffaele Antonelli-Incalzi, Sergio Morini, Antonio Picardi, Katia Aquilano, Umberto Vespasiani-Gentilucci
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-10 (2021)
Abstract Recent studies demonstrated reduced blood lysosomal acid lipase (LAL) activity in patients with nonalcoholic fatty liver disease (NAFLD). We aimed to verify hepatic LAL protein content and activity in in vitro and in vivo models of fat overl
Externí odkaz:
https://doaj.org/article/d2687a261333480896347537214e9a61
Autor:
Rodolfo Sacco, Vincenzo Messina, Umberto Vespasiani Gentilucci, Luigi Elio Adinolfi, Antonio Ascione, Giorgio Barbarini, Angelo Barlattani, Giuseppe Cariti, Raffaele Cozzolongo, Basilio Fimiani, Ruggiero Francavilla, Caterina Furlan, Giovanni Garrucciu, Vincenzo Iovinella, Luca Rinaldi, Massimo Marignani, Paola Begini, Valeria Pace Palitti, Adriano M Pellicelli, Gaetano Scifo, Antonio Facciorusso, Luca Giacomelli, Aashni Shah, Gaetano Bertino, Serena Perazzo, Giampaolo Bresci, Antonio Izzi
Publikováno v:
Drugs in Context, Vol 9, Pp 1-6 (2020)
Background: The once-daily oral combination of daclatasvir (DCV) and sofosbuvir (SOF), with or without ribavirin (RBV), is effective and well tolerated in patients with hepatitis C virus (HCV). However, further field-practice studies are necessary to
Externí odkaz:
https://doaj.org/article/bc98ae33658645cdb80df67be1e48624
Autor:
Federica Tavaglione, Antonio De Vincentis, Oveis Jamialahmadi, Roberta Pujia, Rocco Spagnuolo, Antonio Picardi, Susanna Morano, Luca Valenti, Stefano Romeo, Umberto Vespasiani-Gentilucci
Publikováno v:
JHEP Reports, Vol 3, Iss 3, Pp 100262- (2021)
Background & Aims: Type 2 diabetes is a major driver of fatty liver disease and its long-term complications. The aim of this study was to investigate the individual contribution of inborn and acquired risk factors for severe liver disease in individu
Externí odkaz:
https://doaj.org/article/d28330b5fb2244b5a64744815e3326bf
Autor:
Daphne D’Amato, Antonio De Vincentis, Federica Malinverno, Mauro Viganò, Domenico Alvaro, Maurizio Pompili, Antonino Picciotto, Valeria Pace Palitti, Maurizio Russello, Silvia Storato, Marie Graciella Pigozzi, Vincenza Calvaruso, Elisabetta De Gasperi, Ana Lleo, Antonino Castellaneta, Adriano Pellicelli, Nora Cazzagon, Annarosa Floreani, Luigi Muratori, Stefano Fagiuoli, Grazia Anna Niro, Valentina Feletti, Raffaele Cozzolongo, Natalia Terreni, Marco Marzioni, Rinaldo Pellicano, Pietro Pozzoni, Leonardo Baiocchi, Luchino Chessa, Floriano Rosina, Gaetano Bertino, Maria Vinci, Anna Morgando, Ester Vanni, Gaetano Scifo, Rodolfo Sacco, Maria D’Antò, Valentina Bellia, Roberto Boldizzoni, Silvia Casella, Barbara Omazzi, Guido Poggi, Laura Cristoferi, Alessio Gerussi, Vincenzo Ronca, Rosanna Venere, Francesca Ponziani, Maria Cannavò, Alessandro Mussetto, Rosanna Fontana, Francesco Losito, Evelise Frazzetto, Marco Distefano, Francesca Colapietro, Sara Labanca, Giulia Marconi, Giuseppe Grassi, Giovanni Galati, Sarah Elizabeth O’Donnell, Clara Mancuso, Giacomo Mulinacci, Andrea Palermo, Ernesto Claar, Antonio Izzi, Antonio Picardi, Pietro Invernizzi, Marco Carbone, Umberto Vespasiani-Gentilucci
Publikováno v:
JHEP Reports, Vol 3, Iss 2, Pp 100248- (2021)
Background & aims: Obeticholic acid (OCA) is the second-line treatment approved for patients with primary biliary cholangitis (PBC) and an inadequate response or intolerance to ursodeoxycholic acid. We aimed to evaluate the effectiveness and safety o
Externí odkaz:
https://doaj.org/article/ae3bd5090ee148768daea8f1e94b4ae4
Autor:
Fabrizio Citarella, Alessandro Galletti, Marco Russano, Paolo Gallo, Umberto Vespasiani-Gentilucci, Antonio Picardi, Giuseppe Tonini, Bruno Vincenzi, Daniele Santini
Publikováno v:
Future Science OA, Vol 6, Iss 9 (2020)
Cancer immunotherapy has become a stronghold in modern oncology. Immune checkpoint inhibitors, in particular anti-PD-1 and anti-PD-L1 antibodies, are approved for the treatment of several solid cancers. In the near future, an increasing number of pat
Externí odkaz:
https://doaj.org/article/48e0d6954aea4e07887ec05722af477b
Autor:
Simone Carotti, Katia Aquilano, Francesca Zalfa, Sergio Ruggiero, Francesco Valentini, Maria Zingariello, Maria Francesconi, Giuseppe Perrone, Francesca Alletto, Raffaele Antonelli-Incalzi, Antonio Picardi, Sergio Morini, Daniele Lettieri-Barbato, Umberto Vespasiani-Gentilucci
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in Western countries and is associated with aging and features of metabolic syndrome. Lipotoxicity and oxidative stress are consequent to dysregulation of lip
Externí odkaz:
https://doaj.org/article/5c3b06b1ab484f9082947165f65756e2
Autor:
Moises Muley, Umberto Vespasiani-Gentilucci, Antonio De Vincentis, Marco Santonico, Giorgio Pennazza, Simona Sanguedolce, Cristiana De Luca, Francesco Plotti, Antonio Picardi, Raffaele Antonelli-Incalzi
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233350 (2020)
BACKGROUND:Serum-ascites albumin gradient (SAAG) remains the most sensitive and specific marker for the differentiation of ascites due to portal hypertension from ascites due to other causes. SAAG has some limitations and may fail in selected conditi
Externí odkaz:
https://doaj.org/article/8c715e8a11f54f2d8f6917ae1dcd9af0
Autor:
Francesco Valentini, Giulia Rocchi, Umberto Vespasiani-Gentilucci, Michele Pier Luca Guarino, Annamaria Altomare, Simone Carotti
Publikováno v:
Cells, Vol 11, Iss 3, p 562 (2022)
Fetal life and the first few months after birth represent a plastic age, defined as a “window of opportunity”, as the organism is particularly susceptible to environmental pressures and has to adapt to environmental conditions. Several perturbati
Externí odkaz:
https://doaj.org/article/7f4e37feff864970a25dafdd9ec34d99