Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Umberto L. Fulco"'
Autor:
Yuri Alves de Oliveira Só, Katyanna Sales Bezerra, Ricardo Gargano, Fabio L. L. Mendonça, Janeusa Trindade Souto, Umberto L. Fulco, Marcelo Lopes Pereira Junior, Luiz Antônio Ribeiro Junior
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 755 (2024)
Exploring therapeutic options is crucial in the ongoing COVID-19 pandemic caused by SARS-CoV-2. Nirmatrelvir, which is a potent inhibitor that targets the SARS-CoV-2 Mpro, shows promise as an antiviral treatment. Additionally, Ivermectin, which is a
Externí odkaz:
https://doaj.org/article/fd223d651df34205a8b42eb607ef7260
Autor:
Maxsuel M. F. de Lima, Dory H. A. L. Anselmo, Raimundo Silva, Glauber H. S. Nunes, Umberto L. Fulco, Manoel S. Vasconcelos, Vamberto D. Mello
Publikováno v:
Entropy, Vol 24, Iss 9, p 1225 (2022)
We report an analysis of the distribution of lengths of plant DNA (exons). Three species of Cucurbitaceae were investigated. In our study, we used two distinct κ distribution functions, namely, κ-Maxwellian and double-κ, to fit the length distribu
Externí odkaz:
https://doaj.org/article/bd7894e3db9a437986cbbc15b221b86c
Autor:
Valeska S. de Sena Pereira, Flávio da Silva Emery, Lis Lobo, Fátima Nogueira, Jonas I. N. Oliveira, Umberto L. Fulco, Eudenilson L. Albuquerque, Alejandro M. Katzin, Valter F. de Andrade-Neto
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-11 (2018)
Abstract Background Plasmodium falciparum has shown multidrug resistance, leading to the necessity for the development of new drugs with novel targets, such as the synthesis of isoprenic precursors, which are excellent targets because the pathway is
Externí odkaz:
https://doaj.org/article/af877e10390245d8b11e827d55bcac82
Autor:
Eveline M. Bezerra, Érika C. de Alvarenga, Ricardo P. dos Santos, Jeanlex S. de Sousa, Umberto L. Fulco, Valder N. Freire, Eudenilson L. Albuquerque, Roner F. da Costa
Publikováno v:
RSC Advances. 12:28395-28404
Losartan (LST) is a potent and selective angiotensin II (Ang II) type 1 (AT1) receptor antagonist widely used in the treatment of hypertension. The formation of Ang II is catalyzed by the angiotensin I-converting enzyme (ACE) through proteolytic clea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51248bee0a62b9ebeefca2cbbd2822b0
https://doi.org/10.1039/d2ra04340h
https://doi.org/10.1039/d2ra04340h
Autor:
Katyanna S Bezerra, J. I. N. Oliveira, J. X. Lima Neto, Leonardo D. Machado, E. D. Barbosa, Umberto L. Fulco
Publikováno v:
The Journal of Physical Chemistry B. 125:12972-12980
Envenomation via snakebites occurs largely in areas where it is harder to access the hospital. Its mortality rate and sequelae acquired by the survivors symbolize a big challenge for antivenom therapy. In particular, the homologous phospholipase A2 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12cf3fb4856dad918448fa19f8d2d710
https://doi.org/10.1021/acs.jpcb.1c07298
https://doi.org/10.1021/acs.jpcb.1c07298
Autor:
Maria Karolaynne da Silva, Katyanna S Bezerra, Vinícius Manzoni, Daniel Melo de Oliveira Campos, J. I. N. Oliveira, José X. Lima Neto, Umberto L. Fulco, Stephany C Esmaile
Publikováno v:
New Journal of Chemistry. 45:19487-19496
Stroke is the second most common cause of mortality worldwide and the third most common cause of disability. Stroke causes and hemodynamic consequences are heterogeneous, making blood pressure management in stroke patients complex. Knowing that hyper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb93883e8289918d487e4eabc0fa0db5
https://doi.org/10.1039/d1nj03975j
https://doi.org/10.1039/d1nj03975j
Autor:
J. I. N. Oliveira, Umberto L. Fulco, J. L. S. Santos, A. C. L. Pereira, Valder N. Freire, Katyanna S Bezerra
Publikováno v:
Physical Chemistry Chemical Physics. 23:2836-2845
Melanoma is a type of skin cancer with increasing incidence worldwide and high lethality. Conventional forms of treatment are not effective in advanced cancer stages. Hence, immunotherapeutic approaches have been tested to modulate immune response ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c35551770bfe03ac814912e9f5b6400
https://doi.org/10.1039/d0cp05322h
https://doi.org/10.1039/d0cp05322h
Publikováno v:
Physical Chemistry Chemical Physics. 23:21207-21217
We investigate the interaction between the programmed cell death protein 1 (PD-1) and the programmed cell death ligand 1 (PD-L1), as well as the immuno-oncological drugs pembrolizumab (PEM), and nivolumab (NIV), through quantum chemistry methods base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b3c4c7840c25703108e2686b9d48160
https://doi.org/10.1039/d1cp03064g
https://doi.org/10.1039/d1cp03064g
Autor:
Eudenilson L. Albuquerque, J. F. Vianna, Katyanna S Bezerra, Umberto L. Fulco, J. X. Lima Neto, J. Ivan Nobre Oliveira
Publikováno v:
New Journal of Chemistry. 44:5903-5912
Prostate cancer is the most prevalent malignancy in men, and one of the top causes of cancer death. Great advances have been presented regarding the treatment and understanding of the biology of this disease although, unfortunately, the available the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::681ea5ae0b143eaacf5d4b5a0e5ec09b
https://doi.org/10.1039/c9nj06276a
https://doi.org/10.1039/c9nj06276a
Autor:
Daniel Melo de Oliveira Campos, J. I. N. Oliveira, Eudenilson L. Albuquerque, Katyanna S Bezerra, Umberto L. Fulco, Stephany C Esmaile
Publikováno v:
Physical Chemistry Chemical Physics. 22:15683-15695
The emergent Zika virus (ZIKV) infection has become a threat to global health due to its association with severe neurological abnormalities, namely Guillain-Barré Syndrome (GBS) in adults and Congenital Zika virus Syndrome (CZS) in neonates. Many st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59fa854618ca7f8129b28a44e4a7f5cc
https://doi.org/10.1039/d0cp02254c
https://doi.org/10.1039/d0cp02254c