Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Umberto Kucich"'
Publikováno v:
Journal of Periodontal Research. 33:500-508
Periodontal ligament fibroblasts (PDLFs) are a heterogeneous population of cells that are involved in the normal maintenance, repair and regeneration of both the ligament and adjacent hard tissues. Additionally, the ability of these cells to respond
Autor:
Shidan Lotfi, Ellen Puré, Aili L. Lazaar, Susan K. P. Das, Michael Plotnick, Joel Rosenbloom, Reynold A. Panettieri, Sibyl A. Kane, Norman M. Schechter, Umberto Kucich, Irene Crichton
Publikováno v:
The Journal of Immunology. 169:1014-1020
The hallmarks of chronic, severe asthma include prominent airway inflammation and airway smooth muscle (ASM) hypertrophy and hyperplasia. One of the factors that contribute to the injury and repair process within the airway is activation of proteases
Autor:
Joel Rosenbloom, Paul C. Billings, Pamela S. Howard, Umberto Kucich, William R. Abrams, Beatrice N. Engelsberg, David J. Herrick, Edward J. Macarak
Publikováno v:
Journal of Cellular Biochemistry. 79:261-273
The extracellular matrix (ECM) plays an essential role in bladder structure and function. In this study, expression of beta ig-h3, a recently identified extracellular matrix protein, was investigated in human bladder tissue, and human bladder smooth-
Autor:
Andrew D. Hamilton, Sergio A. Jimenez, Svetlana Gaidarova, Umberto Kucich, William R. Abrams, Nora Sandorfi, J. Rosenbloom, Biagio Saitta, Joel Rosenbloom, Said M. Sebti
Publikováno v:
Arthritis & Rheumatism. 43:1624-1632
Objective To examine the effects of specific inhibition of geranylgeranyl transferase I on the expression of types I and III collagen genes in normal and systemic sclerosis (SSc) dermal fibroblasts in vitro. Methods Fibroblasts from 2 normal subjects
Autor:
Junko Ohkanda, Andrew D. Hamilton, Michelle A. Blaskovich, Umberto Kucich, William R. Abrams, Joel Rosenbloom, J. Rosenbloom, Gloria Shen, Said M. Sebti
Publikováno v:
Biochemical and Biophysical Research Communications. 252:111-116
The TGF-betas are multipotent in their biological activity, modulating cell growth and differentiation as well as extracellular matrix deposition and degradation. Most of these activities involve modulation of gene transcription. However, TGF-beta1 h
Autor:
Umberto Kucich, William R. Abrams, Catherine M. Deveaud, David H. Ewalt, Pamela S. Howard, Edward J. Macarak
Publikováno v:
The Journal of Urology. :1518-1527
Purpose: Fibrosis of bladder tissue is characterized by an abnormal deposition of connective tissue within different layers of the bladder wall, resulting in a low volume, high pressure vesical which may ultimately contribute to renal scarring and fa
Autor:
Waseem Ahmed, Umberto Kucich, William Abrams, Muhammad Bashir, Joan Rosenbloom, Fernando Segade, Robert Mecham, Joel Rosenbloom
Publikováno v:
Connective Tissue Research. 37:263-276
The cytokine transforming growth factor-beta has multiple effects on a wide variety of cell types. These effects include modulation of growth and regulation of gene transcription. In the present work, we demonstrate that TGF-beta1 increases transcrip
Autor:
Sylvia Decker, Robert P. Mecham, J. Rosenbloom, Edward J. Macarak, Umberto Kucich, William R. Abrams, Pamela S. Howard, Joel Rosenbloom
Publikováno v:
Urology. 49:287-292
Objectives To determine the occurrence and potential function of proteins composing elastic microfibrils in the developing bovine bladder. Methods Monospecific antibodies, generated against two well-characterized microfibrillar proteins, microfibril-
Autor:
Carolyn W. Gibson, Umberto Kucich, Gloria Shen, Muhammad M. Bashir, Joel Rosenbloom, P. M. Collier, Sylvia Decker
Publikováno v:
Connective Tissue Research. 32:109-114
Amelogenins are the predominant proteins found in the developing enamel matrix and are believed to play a crucial role in normal mineralization. Although the amelogenin gene is found as a single copy in all species in which it has been examined, mult
Autor:
Muhammad M. Bashir, William R. Abrams, Joan Rosenbloom, Umberto Kucich, Michelle Bacarra, Ming Da Han, Patricia Brown-Augsberger, Robert Mecham, Joel Rosenbloom
Publikováno v:
Biochemistry. 33:593-600
Microfibrils having a diameter of 10-12 nm, found either in association with elastin or independently, are an important component of the extracellular matrix of many tissues. Because isolation of native proteins composing the microfibrils has proven