Zobrazeno 1 - 10
of 300
pro vyhledávání: '"Umberto DIANZANI"'
Autor:
Alessia Provera, Cristina Vecchio, Anteneh Nigussie Sheferaw, Ian Stoppa, Deepika Pantham, Umberto Dianzani, Salvatore Sutti
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35338- (2024)
Metabolic dysfunction associated steatotic liver disease (MASLD) is a progressive pathological condition characterized by the accumulation of triglycerides within hepatocytes that causes histological changes, which, in the long run, might compromise
Externí odkaz:
https://doaj.org/article/165392ea03ad43e38e826b1f18cedd4d
Autor:
Alessia Provera, Naresh Naik Ramavath, Laila Lavanya Gadipudi, Casimiro Luca Gigliotti, Elena Boggio, Cristina Vecchio, Ian Stoppa, Roberta Rolla, Renzo Boldorini, Mario Pirisi, Carlo Smirne, Emanuele Albano, Umberto Dianzani, Salvatore Sutti
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Background and aimsInducible T-cell Co-Stimulator (ICOS) present on T-lymphocytes and its ligand ICOSL expressed by myeloid cells play multiple roles in regulating T-cell functions. However, recent evidence indicates that reverse signalling involving
Externí odkaz:
https://doaj.org/article/f05f4f2e19024bb6aff14a0bd147f227
Autor:
Ian Stoppa, Chiara Dianzani, Nausicaa Clemente, Annalisa Bozza, Valentina Bordano, Sara Garelli, Luigi Cangemi, Umberto Dianzani, Luigi Battaglia
Publikováno v:
Biomolecules, Vol 14, Iss 2, p 238 (2024)
Bone is a site of distant metastases, which are a common cause of morbidity and mortality with a high socio-economic impact, for many malignant tumours. In order to engineer pharmacological therapies that are suitable for this debilitating disease, t
Externí odkaz:
https://doaj.org/article/64c0d3947aa24a85969c2d506d96458c
Autor:
Sara Sacchetti, Matteo Vidali, Teresa Esposito, Stefano Zorzi, Alessia Burgener, Lorenzo Ciccarello, Gianmaria Cammarota, Valentina Zanotti, Luca Giacomini, Mattia Bellan, Mario Pirisi, Ramon Simon Lopez, Umberto Dianzani, Rosanna Vaschetto, Roberta Rolla
Publikováno v:
Diagnostics, Vol 14, Iss 3, p 340 (2024)
Background: Late diagnosis of sepsis is associated with adverse consequences and high mortality rate. The aim of this study was to evaluate the diagnostic value of hematologic research parameters, that reflect the cell morphology of blood cells, avai
Externí odkaz:
https://doaj.org/article/64327779bac34128bed97da370f48e2e
Autor:
Casimiro Luca Gigliotti, Elena Boggio, Francesco Favero, Danny Incarnato, Claudio Santoro, Salvatore Oliviero, Josè Maria Rojo, Silvia Zucchelli, Francesca Persichetti, Gianluca Baldanzi, Umberto Dianzani, Davide Corà
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Costimulatory molecules of the CD28 family play a crucial role in the activation of immune responses in T lymphocytes, complementing and modulating signals originating from the T-cell receptor (TCR) complex. Although distinct functional roles have be
Externí odkaz:
https://doaj.org/article/55eb914dee7e467a8a6a4d3d915b6074
Autor:
Gustavo Ferreira Alves, Ian Stoppa, Eleonora Aimaretti, Chiara Monge, Raffaella Mastrocola, Elisa Porchietto, Giacomo Einaudi, Debora Collotta, Ilaria Bertocchi, Elena Boggio, Casimiro Luca Gigliotti, Nausicaa Clemente, Manuela Aragno, Daniel Fernandes, Carlo Cifani, Christoph Thiemermann, Chiara Dianzani, Umberto Dianzani, Massimo Collino
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Inducible T cell co-stimulator (ICOS), an immune checkpoint protein expressed on activated T cells and its unique ligand, ICOSL, which is expressed on antigen-presenting cells and non-hematopoietic cells, have been extensively investigated in the imm
Externí odkaz:
https://doaj.org/article/1c55e496fa97413c9846216878568c2f
Autor:
Simona Mellone, Chiara Puricelli, Denise Vurchio, Sara Ronzani, Simone Favini, Arianna Maruzzi, Cinzia Peruzzi, Amanda Papa, Alice Spano, Fabio Sirchia, Giorgia Mandrile, Alessandra Pelle, Paolo Rasmini, Fabiana Vercellino, Andrea Zonta, Ivana Rabbone, Umberto Dianzani, Maurizio Viri, Mara Giordano
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: Neurodevelopmental disorders comprise a clinically and genetically heterogeneous group of conditions that affect 2%–5% of children and represents a public health challenge due to complexity of the etiology. Only few patients with unexpl
Externí odkaz:
https://doaj.org/article/edf91342563a4c4b8c9586727480c023
Autor:
Chiara Puricelli, Casimiro Luca Gigliotti, Ian Stoppa, Sara Sacchetti, Deepika Pantham, Anna Scomparin, Roberta Rolla, Stefania Pizzimenti, Umberto Dianzani, Elena Boggio, Salvatore Sutti
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1772 (2023)
Chronic inflammation contributes to the pathogenesis of many diseases, including apparently unrelated conditions such as metabolic disorders, cardiovascular diseases, neurodegenerative diseases, osteoporosis, and tumors, but the use of conventional a
Externí odkaz:
https://doaj.org/article/8467e4ef71cd47deb3a6df40ccb3c0ba
Autor:
Federica Costa, Eleonora Beltrami, Simona Mellone, Sara Sacchetti, Elena Boggio, Casimiro Luca Gigliotti, Ian Stoppa, Umberto Dianzani, Roberta Rolla, Mara Giordano
Publikováno v:
Biomedicines, Vol 11, Iss 4, p 1127 (2023)
Monogenic autoimmune disorders represent an important tool to understand the mechanisms behind central and peripheral immune tolerance. Multiple factors, both genetic and environmental, are known to be involved in the alteration of the immune activat
Externí odkaz:
https://doaj.org/article/1289b07fc1e44e2db079d5c833c339cb
Autor:
Giuseppe Cappellano, Domizia Vecchio, Luca Magistrelli, Nausicaa Clemente, Davide Raineri, Camilla Barbero Mazzucca, Eleonora Virgilio, Umberto Dianzani, Annalisa Chiocchetti, Cristoforo Comi
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 6, Pp 1131-1137 (2021)
Osteopontin is a broadly expressed pleiotropic protein, and is attracting increased attention because of its role in the pathophysiology of several inflammatory, degenerative, autoimmune, and oncologic diseases. In fact, in the last decade, several s
Externí odkaz:
https://doaj.org/article/da8806555c8c4fabb90452e92c4647b3