Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Umberto Bettarini"'
Autor:
Giorgio M. Bressan, Alessandra Ferrari, Maddalena Adorno, Paola Braghetta, Claudio Colonnese, Gennaro Marino, Carmine Vecchione, Angelo Maffei, Giovanni Russo, Umberto Bettarini, Alessandra Aretini, Silvia Maretto, Giuseppe Lembo, Antonella Notte, Paolo Bonaldo, Sandra Soligo, Stefano Piccolo, Giulio Selvetella, Carla Fabbro, Dino Volpin, Giuseppe Cifelli, Sirio Dupont, Michelangelo Cordenonsi, Luca Zacchigna
Publikováno v:
Cell. 124:929-942
TGF-beta proteins are main regulators of blood vessel development and maintenance. Here, we report an unprecedented link between TGF-beta signaling and arterial hypertension based on the analysis of mice mutant for Emilin1, a cysteine-rich secreted g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::406dadb19a931a50cb42f78439a0cca0
https://doi.org/10.1016/j.cell.2005.12.035
https://doi.org/10.1016/j.cell.2005.12.035
Autor:
Giuseppe Lembo, Antonella Notte, Giuseppe Cifelli, Alba Di Pardo, Pierluigi Carullo, Giovanna Antenucci, Giada Mascio, Umberto Bettarini, Alessandro Landolfi, Carmine Vecchione, Alessandro Frati, Daniela Carnevale, Carla L. Busceti, Gian Paolo Cantore, Angelo Maffei, Rosa Carangi, Maria Teresa Gentile
Hypertension can lead to subarachnoid hemorrhage and eventually to cerebral vasospasm. It has been suggested that the latter could be the result of oxidative stress and an inflammatory response evoked by subarachnoid hemorrhage. Because an unavoidabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6a634e4f386d8423e335f588ed0cf35
http://hdl.handle.net/11591/393527
http://hdl.handle.net/11591/393527
Autor:
Umberto Bettarini, Giuseppe Lembo, Carmine Vecchione, Maria Teresa Gentile, Daniela Carnevale, Luca Iorio, Antonio D'Amato, Angelo Maffei, Giovanna Antenucci, Giada Mascio, Germana Cocozza, Alessandro Landolfi, Alba Di Pardo
High blood pressure induces a mechanical stress on vascular walls and evokes oxidative stress and vascular dysfunction. The aim of this study was to characterize the intracellular signaling causing vascular oxidative stress in response to pressure. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80605af61a3f64bc96f336604ee225e1
http://hdl.handle.net/11386/3144477
http://hdl.handle.net/11386/3144477
Publikováno v:
Circulation. 116
Oxidative stress plays a crucial role in the vascular dysfunction present in hypertension. The molecular mechanism involved are not completely elucidated. One of the principal source of oxidative stress at vascular level is the NADPH oxidase enzyme w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cacaa8be7f873db1dd86c1dc8f1bd01b
https://doi.org/10.1161/circ.116.suppl_16.ii_26
https://doi.org/10.1161/circ.116.suppl_16.ii_26
Publikováno v:
Circulation. 116
Subarachnoid hemorrhage is one of the most common events related to hypertensive crisis. The cerebral vasospasm is the complication of subarachnoid hemorrhage that causes more frequently death. Experimental evidences describe a direct relationship be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::970af524e9f51a93a354c41cdf4de3f3
https://doi.org/10.1161/circ.116.suppl_16.ii_73-b
https://doi.org/10.1161/circ.116.suppl_16.ii_73-b
Autor:
Alessandra Aretini, Angelo Maffei, Giuseppe Lembo, Giuseppe Cifelli, Umberto Bettarini, Roberta Poulet, Carmine Vecchione, Maria Teresa Gentile
Background: Nebivolol is a selective β1-adrenergic receptor antagonist that causes a direct vasodilator effect attributed to the action on vascular nitric oxide (NO). This study aimed to investigate whether nebivolol or its metabolites induces NO pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d0d07551f1969281efac4db47f26ce
http://hdl.handle.net/11386/3877488
http://hdl.handle.net/11386/3877488
Autor:
Lucio Pastore, Antonella Notte, Guido Tarone, Alessandra Aretini, Angelo Maffei, Mauro Sbroggiò, Umberto Bettarini, Roberta Poulet, Luca Iorio, Gennaro Marino, Giuseppe Lembo, Maria Teresa Gentile, Carmine Vecchione, Emilio Hirsch
Diabetes mellitus is a main risk factor for vascular diseases. Vascular injury induced by diabetes mellitus is characterized by endothelial dysfunction attributable to an increased oxidative stress. So far, the molecular mechanisms involved in the va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816f100e8f5a9925c26277f2e7dea3f2
http://hdl.handle.net/2318/38763
http://hdl.handle.net/2318/38763
Autor:
Angelo Maffei, Marianna Storto, GianLuca Colussi, Alessandra Aretini, Ornella Azzolino, Mara Brancaccio, Fiorella Altruda, Maria Teresa Gentile, Giuseppe Lembo, Carmine Vecchione, Enrico Patrucco, Guido Tarone, Emilio Hirsch, Lorenzo Silengo, Umberto Bettarini, Roberta Poulet, Mathias P. Wymann, Gennaro Marino, Laura Barberis
Publikováno v:
The Journal of Experimental Medicine
Hypertension affects nearly 20% of the population in Western countries and strongly increases the risk for cardiovascular diseases. In the pathogenesis of hypertension, the vasoactive peptide of the renin-angiotensin system, angiotensin II and its G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f636655d96798c238a41a8031d3498cd
https://pubmed.ncbi.nlm.nih.gov/15824082
https://pubmed.ncbi.nlm.nih.gov/15824082