Zobrazeno 1 - 10
of 313
pro vyhledávání: '"Umar Mahmood"'
Autor:
Nicoleta Sinevici, Christine E. Edmonds, Brian N. Dontchos, Gary Wang, Constance D. Lehman, Steven Isakoff, Umar Mahmood
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-16 (2024)
Abstract Purpose HER3, a member of the EGFR receptor family, plays a central role in driving oncogenic cell proliferation in breast cancer. Novel HER3 therapeutics are showing promising results while recently developed HER3 PET imaging modalities aid
Externí odkaz:
https://doaj.org/article/3cedc56817ad4450ac02fb6c9a7e53d0
Autor:
Ben Lambert, Sassy Molyneux, Claire Marriott Keene, Prabin Dahal, Kasia Stepniewska, Sheetal Silal, Richard Lewis, Sabine Dittrich, Sunil Pokharel, Siyu Chen, Bo Gao, Umar Mahmood, Ricardo Aguas, Marta Wanat, Lisa White, Rima Shretta, Wirichada Pan-Ngum, Ainura Moldokmatova, Caroline Franco, Sompob Saralamba, Jared Norman, Rachel Hounsell, Reshania Naidoo, Melinda C Mills, Lisa J White, Merryn Voysey, Liberty Cantrell, Sophie Dickinson, Billie Andersen-Waine, Angus Ferguson-Lewis, Anastasia Polner, Ma’ayan Amswych, Anastasiia Polner, Claire Keene, Emily Rowe, Kweku Bimpong, Joseph L-H Tsui, Ma'ayan Amswych, Muhammad Kasim, Randolph Ngwafor Anye, Richard Creswell, Sumali Bajaj, Tracy Evans
Publikováno v:
BMJ Open, Vol 14, Iss 3 (2024)
Objective Testing for COVID-19 was a key component of the UK’s response to the COVID-19 pandemic. This strategy relied on positive individuals self-isolating to reduce transmission, making isolation the lynchpin in the public health approach. There
Externí odkaz:
https://doaj.org/article/e7080cbb8e1e4a56a3a5fcb7cc8dc050
Publikováno v:
Optics, Vol 4, Iss 2, Pp 340-350 (2023)
Image-guided liver biopsies can improve their success rate when combined with the optical detection of Indocyanine Green (ICG) fluorescence accumulated in tumors. Previous works used a camera coupled to a thin borescope to capture and quantify images
Externí odkaz:
https://doaj.org/article/f845aed62ee8484788765ce75bffe023
Autor:
Ivan bermejo Altamar, MD, James Wong, MD, PhD, Sujeev Mathur, MD, MB, Hannah Bellsham-Revell, MD, Aaron Bell, MD, Umar Mahmood, MD, Reza Razavi, MD, William Regan, MD, Kuberan Pushparajah, MD, BMSc
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 26, Iss , Pp 100044- (2024)
Externí odkaz:
https://doaj.org/article/5528873c39694bcfb3726c4bf2e3bfe9
Autor:
Ivan bermejo Altamar, MD, James Wong, MD, PhD, Sujeev Mathur, MD, MB, Hannah Bellsham-Revell, MD, Aaron Bell, MD, Umar Mahmood, MD, Reza Razavi, MD, Kuberan Pushparajah, MD, BMSc
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 26, Iss , Pp 100527- (2024)
Externí odkaz:
https://doaj.org/article/1c6c4021774f4e8e84cea757372ff90c
Autor:
Ashish Chikermane, Konstantinos Dimopoulos, Michael A Gatzoulis, Sonya V Babu-Narayan, Zdenka Reinhardt, Natali AY Chung, Paul F Clift, Dirk Wilson, Petra Jenkins, Rachel Knowles, Bernadette Khodaghalian, Benjamin Smith, Owen Miller, Umar Mahmood, Heba Nashat, Aoife Cleary, John M Simpson, Clive Lewis, Catherine Head, Sian Chivers, Tara Bharucha, Dominic Hares, Piers EF Daubeney, Caroline B Jones, Milos Prica, James Anthony, Victoria Jowett, Antonia Hardiman, Frances A Bu'Lock, Tristan KW Ramcharan, Jennifer Shortland, Andrew Tometzki, David S Crossland, Leila Rittey, Olga Panagiotopoulou, Muhammad Najih L
Publikováno v:
Open Heart, Vol 10, Iss 2 (2023)
Background COVID-19 has caused significant worldwide morbidity and mortality. Congenital heart disease (CHD) is likely to increase vulnerability and understanding the predictors of adverse outcomes is key to optimising care.Objective Ascertain the im
Externí odkaz:
https://doaj.org/article/aa0a267f0ab34f7ea87523ab44afe4f7
Autor:
Yousef Khazaei Monfared, Pedram Heidari, Samuel J. Klempner, Umar Mahmood, Aparna R. Parikh, Theodore S. Hong, Matthew R. Strickland, Shadi A. Esfahani
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2761 (2023)
DNA is an organic molecule that is highly vulnerable to chemical alterations and breaks caused by both internal and external factors. Cells possess complex and advanced mechanisms, including DNA repair, damage tolerance, cell cycle checkpoints, and c
Externí odkaz:
https://doaj.org/article/80e7bf35a72b4e689356fed3aede8204
Autor:
Tonya M. Gilbert, Nicole R. Zürcher, Mary C. Catanese, Chieh-En J. Tseng, Maria A. Di Biase, Amanda E. Lyall, Baileigh G. Hightower, Anjali J. Parmar, Anisha Bhanot, Christine J. Wu, Matthew L. Hibert, Minhae Kim, Umar Mahmood, Steven M. Stufflebeam, Frederick A. Schroeder, Changning Wang, Joshua L. Roffman, Daphne J. Holt, Douglas N. Greve, Ofer Pasternak, Marek Kubicki, Hsiao-Ying Wey, Jacob M. Hooker
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Gene transcription is known to vary with age and sex, although the underlying mechanisms are unresolved. Here, the authors show that epigenetic enzymes known as HDACs, which regulate gene transcription, are increasingly expressed with age in the livi
Externí odkaz:
https://doaj.org/article/fd891fe0074148ad83476fb18c8b1d21
Autor:
Carolina de Aguiar Ferreira, Pedram Heidari, Bahar Ataeinia, Nicoleta Sinevici, Alyssa Granito, Hritik Mahajan Kumar, Eric Wehrenberg-Klee, Umar Mahmood
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1460 (2022)
Although immune checkpoint inhibitors (ICI) have revolutionized cancer management, patient response can be heterogeneous, and the development of ICI resistance is increasingly reported. Novel treatment strategies are necessary not only to expand the
Externí odkaz:
https://doaj.org/article/32c52d25bf914713bd2d3d544cafb437
Autor:
Nicoleta Sinevici, Bahar Ataeinia, Veronica Zehnder, Kevin Lin, Lauren Grove, Pedram Heidari, Umar Mahmood
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Triple Negative Breast Cancer (TNBC) is an aggressive form of Breast Cancer (BC). Numerous kinase inhibitors (KI) targeting different pathway nodes have shown limited benefit in the clinical setting. In this study, we aim to characterize the extent o
Externí odkaz:
https://doaj.org/article/28ff39c286a44025976bf050a3465576