The genetic dissection of fetal haemoglobin persistence in sickle cell disease in Nigeria.

Autor: Ojewunmi OO; School of Cancer and Pharmaceutical Sciences, King's College London, 123 Coldharbour Lane, London SE5 9NU, United Kingdom.; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, United Kingdom., Adeyemo TA; Department of Haematology and Blood Transfusion, College of Medicine, University of Lagos, P.M.B 12003, Lagos, Nigeria., Oyetunji AI; Sickle Cell Foundation Nigeria, Ishaga Road, Idi-Araba, P.O. Box 3463, Lagos, Nigeria., Inyang B; Department of Medical Biochemistry, College of Health Sciences, University of Abuja, Mohammed Maccido Road, Airport Road, P.M.B 117, Abuja, Nigeria., Akinrindoye A; Sickle Cell Foundation Nigeria, Ishaga Road, Idi-Araba, P.O. Box 3463, Lagos, Nigeria.; School of Science, University of Greenwich, Central Avenue, Chatham Maritime, Kent ME4 4TB, United Kingdom., Mkumbe BS; Department of Biochemistry and Molecular Biology, Muhimbili University of Health and Allied Sciences, P.O. Box 65001, United Nations Rd, Dar es Salaam, Tanzania.; Department of Artificial Intelligence and Innovative Medicine, Tohoku University Graduate School of Medicine, 980-8573, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan., Gardner K; School of Cancer and Pharmaceutical Sciences, King's College London, 123 Coldharbour Lane, London SE5 9NU, United Kingdom.; Clinical Haematology, Haematology and Oncology Directorate, Guy's Hospital, Great Maze Pond, London SE1 9RT, United Kingdom., Rooks H; School of Cancer and Pharmaceutical Sciences, King's College London, 123 Coldharbour Lane, London SE5 9NU, United Kingdom., Brewin J; School of Cancer and Pharmaceutical Sciences, King's College London, 123 Coldharbour Lane, London SE5 9NU, United Kingdom.; Department of Haematological Medicine, King's College Hospital, London SE5 9RS, United Kingdom., Patel H; NIHR BioResource Centre Maudsley, NIHR Maudsley Biomedical Research Centre (BRC) at South London and Maudsley NHS Foundation Trust (SLaM) and Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, 16 De Crespigny Park, London SE5 8AB, United Kingdom., Lee SH; NIHR BioResource Centre Maudsley, NIHR Maudsley Biomedical Research Centre (BRC) at South London and Maudsley NHS Foundation Trust (SLaM) and Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, 16 De Crespigny Park, London SE5 8AB, United Kingdom., Chung R; NIHR BioResource Centre Maudsley, NIHR Maudsley Biomedical Research Centre (BRC) at South London and Maudsley NHS Foundation Trust (SLaM) and Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, 16 De Crespigny Park, London SE5 8AB, United Kingdom., Rashkin S; St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, United States., Kang G; St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, United States., Chianumba R; Centre of Excellence for Sickle Cell Disease Research and Training (CESRTA), University of Abuja, Mohammed Maccido Road, Airport Road, P.M.B 117, Abuja, Nigeria., Sangeda R; Department of Pharmaceutical Microbiology, Muhimbili University of Health and Allied Sciences, P.O. Box 65001, Dar es Salaam, Tanzania., Mwita L; Department of Pharmaceutical Microbiology, Muhimbili University of Health and Allied Sciences, P.O. Box 65001, Dar es Salaam, Tanzania., Isa H; Centre of Excellence for Sickle Cell Disease Research and Training (CESRTA), University of Abuja, Mohammed Maccido Road, Airport Road, P.M.B 117, Abuja, Nigeria.; Department of Haematology and Blood Transfusion, University of Abuja Teaching Hospital, Gwagwalada, P.M.B. 228, Gwagwalada, FCT Abuja, Nigeria., Agumadu UN; Department of Paediatrics, College of Health Sciences, University of Abuja, Mohammed Maccido Road, Airport Road, P.M.B 117, Abuja, Nigeria., Ekong R; Research Department of Genetics, Evolution and Environment, University College London, Gower Street, London WC1E 6BT, United Kingdom., Faruk JA; Department of Paediatrics, Ahmadu Bello University/Ahmadu Bello University Teaching Hospital, P.M.B 006, Zaria, Nigeria., Jamoh BY; Department of Internal Medicine, Ahmadu Bello University/Ahmadu Bello University Teaching Hospital, P.M.B 006, Zaria, Nigeria., Adebiyi NM; Department of Paediatrics, Ahmadu Bello University/Ahmadu Bello University Teaching Hospital, P.M.B 006, Zaria, Nigeria., Umar IA; Department of Biochemistry, Faculty of Life Sciences, Ahmadu Bello University, Sokoto Road, Samaru, P.M.B 006, Zaria, Nigeria., Hassan A; Department of Haematology and Blood Transfusion, Ahmadu Bello University, Sokoto Road, Samaru, P.M.B 006, Zaria, Nigeria., Grace C; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Centre for Human Genetics, Roosevelt Drive, Oxford OX37BN, United Kingdom., Goel A; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Centre for Human Genetics, Roosevelt Drive, Oxford OX37BN, United Kingdom., Inusa BPD; Evelina London Children's Hospital, Guy's and St. Thomas' NHS Foundation Trust, Westminster Bridge Rd, London SE1 7EH, United Kingdom., Falchi M; Department of Twin Research and Genetic Epidemiology, King's College London, St Thomas' Hospital, Westminster Bridge Road, London SE1 7EH, United Kingdom., Nkya S; Department of Biochemistry and Molecular Biology, Muhimbili University of Health and Allied Sciences, P.O. Box 65001, United Nations Rd, Dar es Salaam, Tanzania.; Tanzania Human Genetics Organisation, Sickle Cell Centre, 1 Kipalapala Street, Dar es Salaam, Tanzania.; Sickle Cell Program, Muhimbili University of Health and Allied Sciences, P.O. Box 65001, United Nations Rd, Dar es Salaam, Tanzania.; Department of Haematology and Blood Transfusion, Muhimbili University of Health and Allied Science, P.O. Box 65001, Dar es Salaam, Tanzania., Makani J; Sickle Cell Program, Muhimbili University of Health and Allied Sciences, P.O. Box 65001, United Nations Rd, Dar es Salaam, Tanzania.; Department of Haematology and Blood Transfusion, Muhimbili University of Health and Allied Science, P.O. Box 65001, Dar es Salaam, Tanzania.; Centre for Haematology, Department of Immunology & Inflammation, Imperial College London, Commonwealth Building, Hammersmith Campus, Du Cane Rd, London W12 0NN, United Kingdom., Ahmad HR; Department of Paediatrics, Ahmadu Bello University/Ahmadu Bello University Teaching Hospital, P.M.B 006, Zaria, Nigeria., Nnodu O; Centre of Excellence for Sickle Cell Disease Research and Training (CESRTA), University of Abuja, Mohammed Maccido Road, Airport Road, P.M.B 117, Abuja, Nigeria.; Department of Haematology and Blood Transfusion, University of Abuja Teaching Hospital, Gwagwalada, P.M.B. 228, Gwagwalada, FCT Abuja, Nigeria., Strouboulis J; School of Cancer and Pharmaceutical Sciences, King's College London, 123 Coldharbour Lane, London SE5 9NU, United Kingdom., Menzel S; School of Cancer and Pharmaceutical Sciences, King's College London, 123 Coldharbour Lane, London SE5 9NU, United Kingdom.

Publikováno v: Human molecular genetics [Hum Mol Genet] 2024 May 04; Vol. 33 (10), pp. 919-929.

Role of the IL8 rs4073 polymorphism in central nervous system toxicity in patients receiving multidrug-resistant tuberculosis treatment.

Autor: Badamasi IM; Pharmacogenomic Unit, Department of Human Anatomy, Faculty of Basic Medical Sciences - FBMS - College of Medicine, Bayero University, Kano, Kano, Nigeria., Muhammad M; Pharmacogenomic Unit, Department of Human Anatomy, Faculty of Basic Medical Sciences - FBMS - College of Medicine, Bayero University, Kano, Kano, Nigeria., Umar AA; Pharmacogenomic Unit, Department of Human Anatomy, Faculty of Basic Medical Sciences - FBMS - College of Medicine, Bayero University, Kano, Kano, Nigeria., Madugu UM; Pharmacogenomic Unit, Department of Human Anatomy, Faculty of Basic Medical Sciences - FBMS - College of Medicine, Bayero University, Kano, Kano, Nigeria., Gadanya MA; Department of Community Medicine, Faculty of Clinical Sciences, Bayero University, Kano, Kano, Nigeria., Aliyu IA; Department of Medical Laboratory Science, Faculty of Allied Health Sciences - FAHS - Bayero University, Kano, Kano, Nigeria., Kabir IM; Department of Medical Laboratory Science, Faculty of Allied Health Sciences - FAHS - Bayero University, Kano, Kano, Nigeria., Umar IA; Kano State TB and Leprosy Control Program, Kano State Ministry of Health, Kano, Nigeria., Johnson O; Kano State Infectious Disease Hospital, Kano State Ministry of Health, Kano, Nigeria., Stanslas J; Pharmacotherapeutics Lab, Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia.

Publikováno v: Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia [J Bras Pneumol] 2024 Feb 12; Vol. 50 (1), pp. e20230338. Date of Electronic Publication: 2024 Feb 12 (Print Publication: 2024).

Kolaviron pre-treatment suppresses 7, 12 dimethylbenzanthracene-induced alterations in estrogen receptor-α, CYP 1A1, oxidative stress and inflammation in female Wistar rats.

Autor: Attah OC; Department of Biochemistry, Faculty of Life Sciences, Ahmadu Bello University, Zaria, Nigeria., Umar IA; Department of Biochemistry, Faculty of Life Sciences, Ahmadu Bello University, Zaria, Nigeria., Ameh DA; Department of Biochemistry, Faculty of Life Sciences, Ahmadu Bello University, Zaria, Nigeria., Forcados GE; Department of Biochemistry, Faculty of Life Sciences, Ahmadu Bello University, Zaria, Nigeria., Muhammad A; Department of Biochemistry, Faculty of Life Sciences, Ahmadu Bello University, Zaria, Nigeria., Sani I; Department of Biochemistry, Faculty of Life Sciences, Ahmadu Bello University, Zaria, Nigeria.

Publikováno v: Journal of food biochemistry [J Food Biochem] 2022 Feb; Vol. 46 (2), pp. e13984. Date of Electronic Publication: 2021 Dec 22.

Bioguided fractionation of hypoglycaemic component in methanol extract of Vernonia amygdalina: an in vivo study.

Autor: Okoduwa SIR; Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria.; Directorate of Research and Development, Nigerian Institute of Leather and Science Technology, Zaria, Nigeria., Umar IA; Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria., James DB; Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria., Inuwa HM; Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria., Habila JD; Department of Chemistry, Ahmadu Bello University, Zaria, Nigeria., Venditti A; Department of Chemistry, 'Sapienza' University of Rome, Rome, Italy.

Publikováno v: Natural product research [Nat Prod Res] 2021 Dec; Vol. 35 (24), pp. 5943-5947. Date of Electronic Publication: 2020 Aug 13.

Isolation and Structural Elucidation of Novel Antidiabetic Compounds from Leaves of Momordica balsamina Linn and Leptadenia hastata (Pers) Decne.

Autor: Kabir N; Department of Biochemistry, Faculty of Science, Federal University Dutse, Jigawa state-Nigeria., Umar IA; Department of Biochemisty, Faculty of Life Sciences, Ahmadu Bello University Zaria, Kaduna State-Nigeria., Dama HA; Department of Chemistry, Faculty of Physical Sciences, Ahmadu Bello University Zaria, Kaduna State-Nigeria., James DB; Department of Biochemisty, Faculty of Life Sciences, Ahmadu Bello University Zaria, Kaduna State-Nigeria., Inuwa HM; Department of Biochemisty, Faculty of Life Sciences, Ahmadu Bello University Zaria, Kaduna State-Nigeria.

Publikováno v: Iranian journal of pharmaceutical research : IJPR [Iran J Pharm Res] 2021 Spring; Vol. 20 (2), pp. 390-402.