Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Umair Seemab"'
Autor:
Henri Leinonen, Jianye Zhang, Laurence M. Occelli, Umair Seemab, Elliot H. Choi, Luis Felipe L.P. Marinho, Janice Querubin, Alexander V. Kolesnikov, Anna Galinska, Katarzyna Kordecka, Thanh Hoang, Dominik Lewandowski, Timothy T. Lee, Elliott E. Einstein, David E. Einstein, Zhiqian Dong, Philip D. Kiser, Seth Blackshaw, Vladimir J. Kefalov, Marcin Tabaka, Andrzej Foik, Simon M. Petersen-Jones, Krzysztof Palczewski
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Inherited retinopathies are devastating diseases that in most cases lack treatment options. Disease-modifying therapies that mitigate pathophysiology regardless of the underlying genetic lesion are desirable due to the diversity of mutations
Externí odkaz:
https://doaj.org/article/b5b9cf370c114fd1b6b378a34d01cbf7
Autor:
Sonja Korhonen, Katja Stenberg, Umair Seemab, Piia Bartos, Katariina Mäkiniemi, Jørgen Kjems, Daniel Miotto Dupont, Astrid Subrizi
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 4, Pp 102352- (2024)
Ocular diseases create a significant economic burden and decrease in quality of life worldwide. Drugs and carrier molecules that penetrate ocular tissues after intravenous administration are needed for more efficient and patient-friendly treatment of
Externí odkaz:
https://doaj.org/article/f5d64ecff7614091bfcc85a7b1d0e6be
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54630 (2013)
The observed genetic alterations of various extracellular and intracellular WNT (Wingless, Int-1 proto-oncogene) signaling components can result in an increase or decrease in gene expression, and hence can be obstructed proficiently. These genetics t
Externí odkaz:
https://doaj.org/article/9319e21754dd43979b86444396e7d344
Autor:
Florence Bietrix, Petr Pavlis, Umair Seemab, Marian Hajduch, Jing Tang, Jani Saarela, Ziaurrehman Tanoli, Farhan Alam, Matthew D. Hall, Krister Wennerberg, Min Shen, Jehad Aldahdooh, Yinyin Wang, Evgeny Kulesskiy, Kyle R. Brimacombe, Markus Vähä-Koskela, Philip Gribbon, Andrea Zaliani, Maddalena Fratelli
Publikováno v:
Briefings in Bioinformatics
Tanoli, Z, Aldahdooh, J, Alam, F, Wang, Y, Seemab, U, Fratelli, M, Pavlis, P, Hajduch, M, Bietrix, F, Gribbon, P, Zaliani, A, Hall, M D, Shen, M, Brimacombe, K, Kulesskiy, E, Saarela, J, Wennerberg, K, Vähä-Koskela, M & Tang, J 2022, ' Minimal information for chemosensitivity assays (MICHA) : a next-generation pipeline to enable the FAIRification of drug screening experiments ', Briefings in Bioinformatics, vol. 23, no. 1 . https://doi.org/10.1093/bib/bbab350
bioRxiv
article-version (status) pre
article-version (number) 1
Tanoli, Z, Aldahdooh, J, Alam, F, Wang, Y, Seemab, U, Fratelli, M, Pavlis, P, Hajduch, M, Bietrix, F, Gribbon, P, Zaliani, A, Hall, M D, Shen, M, Brimacombe, K, Kulesskiy, E, Saarela, J, Wennerberg, K, Vähä-Koskela, M & Tang, J 2022, ' Minimal information for chemosensitivity assays (MICHA) : a next-generation pipeline to enable the FAIRification of drug screening experiments ', Briefings in Bioinformatics, vol. 23, no. 1 . https://doi.org/10.1093/bib/bbab350
bioRxiv
article-version (status) pre
article-version (number) 1
Chemosensitivity assays are commonly used for preclinical drug discovery and clinical trial optimization. However, data from independent assays are often discordant, largely attributed to uncharacterized variation in the experimental materials and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51c45aaa64d0aac50cf942f4e0a420ef
https://doi.org/10.1101/2020.12.03.409409
https://doi.org/10.1101/2020.12.03.409409
Publikováno v:
Briefings in Bioinformatics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::5661e216014a3e184acf4dc9fff05720
Autor:
Hani El-Nezami, Joseph Ndika, Vittorio Fortino, Umair Seemab, Piia Karisola, Wing-Lam Poon, Harri Alenius
Publikováno v:
Nanotoxicology. 13(10)
After over a decade of nanosafety research, it is indisputable that the vast majority of nano-sized particles induce a plethora of adverse cellular responses - the severity of which is linked to the material's physicochemical properties. Differentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc9b8fd7ab799a3f61e732202ec3483
https://pubmed.ncbi.nlm.nih.gov/31519129
https://pubmed.ncbi.nlm.nih.gov/31519129
Publikováno v:
Genomics, Proteomics & Bioinformatics
Recent advances in the development of high-throughput tools have significantly revolutionized our understanding of molecular mechanisms underlying normal and dysfunctional biological processes. Here we present a novel computational tool, transcriptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e84ca452c82b81f7f52b0c37691aba2
https://doi.org/10.1016/j.gpb.2012.06.007
https://doi.org/10.1016/j.gpb.2012.06.007
Publikováno v:
Bioinformation
In human, WNT gene clusters are highly conserved at specie level and associated with carcinogenesis. Among them, WNT-10A and WNT-6 genes clustered in chromosome 2q35 are homologous to WNT-10B and WNT-1 located in chromosome 12q13, respectively. In an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48573948600bd133c9c0fc227ccf59cc
http://europepmc.org/articles/PMC3280488
http://europepmc.org/articles/PMC3280488