Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Umaimainthan, Palendira"'
Autor:
Xinyu Bai, Grace H. Attrill, Tuba N. Gide, Peter M. Ferguson, Kazi J. Nahar, Ping Shang, Ismael A. Vergara, Umaimainthan Palendira, Ines Pires da Silva, Matteo S. Carlino, Alexander M. Menzies, Georgina V. Long, Richard A. Scolyer, James S. Wilmott, Camelia Quek
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The biological underpinnings of therapeutic resistance to immune checkpoint inhibitors (ICI) in adolescent and young adult (AYA) melanoma patients are incompletely understood. Here, we characterize the immunogenomic profile and spatial archi
Externí odkaz:
https://doaj.org/article/4e3968539ed44b5d8e921475912375ae
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 5256-5263 (2022)
Over the past decade, our understanding of human diseases has rapidly grown from the rise of single-cell spatial biology. While conventional tissue imaging has focused on visualizing morphological features, the development of multiplex tissue imaging
Externí odkaz:
https://doaj.org/article/da86f0d8ed5e4b20be84d245ed0e4194
Autor:
Sarah Baird, Caroline L Ashley, Felix Marsh‐Wakefield, Sibel Alca, Thomas M Ashhurst, Angela L Ferguson, Hannah Lukeman, Claudio Counoupas, Jeffrey J Post, Pamela Konecny, Adam Bartlett, Marianne Martinello, Rowena A Bull, Andrew Lloyd, Alice Grey, Owen Hutchings, Umaimainthan Palendira, Warwick J Britton, Megan Steain, James A Triccas
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 8, Pp n/a-n/a (2023)
Abstract Objectives SARS‐CoV‐2 infection causes a spectrum of clinical disease presentation, ranging from asymptomatic to fatal. While neutralising antibody (NAb) responses correlate with protection against symptomatic and severe infection, the c
Externí odkaz:
https://doaj.org/article/b5bb073a3e354d3785e5be131c95ec23
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 5, Pp n/a-n/a (2023)
Abstract The link between Epstein–Barr virus (EBV) and multiple sclerosis (MS) has puzzled researchers since it was first discovered over 40 years ago. Until that point, EBV was primarily viewed as a cancer‐causing agent, but the culmination of e
Externí odkaz:
https://doaj.org/article/fb8e86df17e34a568fd4d71c379b0a0c
Autor:
Claudio Counoupas, Matt D. Johansen, Alberto O. Stella, Duc H. Nguyen, Angela L. Ferguson, Anupriya Aggarwal, Nayan D. Bhattacharyya, Alice Grey, Owen Hutchings, Karishma Patel, Rezwan Siddiquee, Erica L. Stewart, Carl G. Feng, Nicole G. Hansbro, Umaimainthan Palendira, Megan C. Steain, Bernadette M. Saunders, Jason K. K. Low, Joel P. Mackay, Anthony D. Kelleher, Warwick J. Britton, Stuart G. Turville, Philip M. Hansbro, James A. Triccas
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-10 (2021)
Abstract Global control of COVID-19 requires broadly accessible vaccines that are effective against SARS-CoV-2 variants. In this report, we exploit the immunostimulatory properties of bacille Calmette-Guérin (BCG), the existing tuberculosis vaccine,
Externí odkaz:
https://doaj.org/article/54cf1269f483428f921decb5fa5ac562
Autor:
Kazi J. Nahar, Felix Marsh-Wakefield, Robert V. Rawson, Tuba N. Gide, Angela L. Ferguson, Ruth Allen, Camelia Quek, Ines Pires da Silva, Stephen Tattersal, Christopher J. Kiely, Neomal Sandanayake, Matteo S. Carlino, Geoff McCaughan, James S. Wilmott, Richard A. Scolyer, Georgina V. Long, Alexander M. Menzies, Umaimainthan Palendira
Publikováno v:
JCI Insight, Vol 7, Iss 21 (2022)
Immune-related adverse events represent a major hurdle to the success of immunotherapy. The immunological mechanisms underlying their development and relation to antitumor responses are poorly understood. By examining both systemic and tissue-specifi
Externí odkaz:
https://doaj.org/article/3735f33fbccb4897a34d7c5e7b464466
Autor:
Ellis Armitage, Diana Quan, Manuela Flórido, Umaimainthan Palendira, James A. Triccas, Warwick J. Britton
Publikováno v:
Vaccines, Vol 11, Iss 10, p 1549 (2023)
Mycobacterium tuberculosis is a major human pathogen, and new vaccines are needed to prevent transmission. Mucosal vaccination may confer protection against M. tuberculosis by stimulating tissue-resident memory (TRM) CD4+ T cells in the lungs. The ch
Externí odkaz:
https://doaj.org/article/c73951220ee147429e232ac2386938ec
Autor:
Grace H. Attrill, Hansol Lee, Annie T. Tasker, Nurudeen A. Adegoke, Angela L. Ferguson, Ines Pires da Silva, Robyn P. M. Saw, John F. Thompson, Umaimainthan Palendira, Georgina V. Long, Peter M. Ferguson, Richard A. Scolyer, James S. Wilmott
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
While the tumor immune microenvironment (TIME) of metastatic melanoma has been well characterized, the primary melanoma TIME is comparatively poorly understood. Additionally, although the association of tumor-infiltrating lymphocytes with primary mel
Externí odkaz:
https://doaj.org/article/a796eeddfd624bc8b912dd7adc427415
Autor:
Felix Marsh-Wakefield, Angela L Ferguson, Ken Liu, Cositha Santhakumar, Geoffrey McCaughan, Umaimainthan Palendira
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Hepatocellular carcinoma (HCC) is a common and deadly cancer worldwide. Many factors contribute to mortality and place an individual at high risk of developing HCC, including viral infection, alcohol intake, metabolic-associated disease, autoimmunity
Externí odkaz:
https://doaj.org/article/987134dc16a04c899711d41b8b7343b3
Autor:
Andrew J Colebatch, John F Thompson, Serigne Lo, Ines Pires da Silva, Georgina V Long, Richard A Scolyer, Kazi J Nahar, Tasnia Ahmed, Umaimainthan Palendira, Alexander M Menzies, Jordan W Conway, Matteo S Carlino, Ismael A Vergara, James S Wilmott, Grace Heloise Attrill, Carina N Owen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/bc42aa6825a44fdb8db135c1150e97e4