Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Uma Sinha-Datta"'
Autor:
Marcia Bellon, Valentina Cecchinato, Genoveffa Franchini, Risaku Fukumoto, Uma Sinha-Datta, Cynthia A. Pise-Masison, Robyn Washington Parks, Vibeke Andresen, Christophe Nicot, Valerio W. Valeri
Publikováno v:
Blood. 118:1549-1559
Disease development in human T-cell leukemia virus type 1 (HTLV-1)–infected individuals is positively correlated with the level of integrated viral DNA in T cells. HTLV-1 replication is positively regulated by Tax and Rex and negatively regulated b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85caff135921e88c1e9891d57973cc4c
https://doi.org/10.1182/blood-2010-06-293340
https://doi.org/10.1182/blood-2010-06-293340
Publikováno v:
Journal of Biological Chemistry. 281:23414-23424
Whereas adaptive immunity has been extensively studied, very little is known about the innate immunity of the host to HTLV-I infection. HTLV-I-infected ATL patients have pronounced immunodeficiency associated with frequent opportunistic infections, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22995e2888ed09ceb69c5689d5766a8
https://doi.org/10.1074/jbc.m600684200
https://doi.org/10.1074/jbc.m600684200
Autor:
Izumi Horikawa, Abhik Datta, Mirdad Kazanji, Janitzia C. Sigler-Nicot, J. Carl Barrett, Christophe Nicot, Eriko Michishita, Uma Sinha-Datta, Megan Brown
Publikováno v:
Blood. 104:2523-2531
In immortal cells, the existence of a mechanism for the maintenance of telomere length is critical. In most cases this is achieved by the reactivation of telomerase, a cellular reverse transcriptase that prevents telomere shortening. Here we report t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ee8b087cde75e303c7f00cedb631c6
https://doi.org/10.1182/blood-2003-12-4251
https://doi.org/10.1182/blood-2003-12-4251
Publikováno v:
Biosimilars. :83
Uma Sinha-Datta, Srijit Khan, Dhananjay WadgaonkarFast Trak, GE Healthcare Life Science, John F Welch Technology Centre, Bangalore, IndiaAbstract: In the biosimilar eon, where various analytical platforms are needed to show biosimilarity, we demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a2fd3c8927de9fa3d14ed02fb6779c
https://doi.org/10.2147/bs.s85537
https://doi.org/10.2147/bs.s85537
Publikováno v:
Journal of virology. 86(8)
Human T-cell leukemia virus type 1 (HTLV-1) is a complex retrovirus associated with the lymphoproliferative disease adult T-cell leukemia/lymphoma (ATL) and the neurodegenerative disorder tropical spastic paraparesis/HTLV-1-associated myelopathy (TSP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c91a5e2987da1b45df3faf99e6de878
https://pubmed.ncbi.nlm.nih.gov/22318152
https://pubmed.ncbi.nlm.nih.gov/22318152
Publikováno v:
The Journal of biological chemistry. 282(19)
Human T-cell lymphotrophic virus type I Rex and p30 are both RNA binding regulatory proteins. Rex is a protein that interacts with a responsive element and stimulates nuclear export of incompletely spliced viral RNAs thereby increasing production of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a210153cdb673f8c35b40b2ccd64b89c
https://pubmed.ncbi.nlm.nih.gov/17360706
https://pubmed.ncbi.nlm.nih.gov/17360706
Autor:
Miroslav Dundr, Uma Sinha-Datta, Sofiane Ghorbel, Megan Brown, Genoveffa Franchini, Christophe Nicot
Publikováno v:
The Journal of biological chemistry. 281(48)
Human T-cell leukemia virus type I is the etiological agent of adult T-cell leukemia/lymphoma, an aggressive and fatal lymphoproliferative malignancy. The virus has evolved strategies to escape immune clearance by remaining latent in most infected ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4288c983fac260ec847132b5743623
https://pubmed.ncbi.nlm.nih.gov/17008317
https://pubmed.ncbi.nlm.nih.gov/17008317
Autor:
Yves Lepelletier, Thomas A. Waldmann, Olivier Hermine, Abhik Datta, Uma Sinha-Datta, Christophe Nicot, Ali Bazarbachi, Marcia Bellon, Danielle Canioni
Publikováno v:
Blood
Blood, American Society of Hematology, 2006, 108, pp.1021-1029
Blood, American Society of Hematology, 2006, 108, pp.1021-1029
The antiviral thymidine analog azidothymidine (AZT) is used to treat several virus-associated human cancers. However, to date the mechanism of AZT action remains unclear and thus, reasons for treatment failure are unknown. Adult T-cell leukemia/lymph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e03f6af26aae52eb4714b10e8ec8fce0
https://hal.archives-ouvertes.fr/hal-00022487
https://hal.archives-ouvertes.fr/hal-00022487
Publikováno v:
Biochemical and biophysical research communications. 332(3)
The segments 10 (S10) of the 11 double stranded RNA genomes from Antheraea mylitta cytoplasmic polyhedrosis virus (AmCPV) encoding a novel polyhedrin polypeptide was converted to cDNA, cloned, and sequenced. Three cDNA clones consisting of 1502 (AmCP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e82dd6f1e73f4bfb1bf9ea31090ec76
https://pubmed.ncbi.nlm.nih.gov/15907799
https://pubmed.ncbi.nlm.nih.gov/15907799
Autor:
Genoveffa Franchini, Cynthia A. Pise-Masison, Robyn Washington Parks, Vibeke Andresen, Uma Sinha-Datta, Risaku Fukumoto, Valentina Cecchinato, Christophe Nicot
Publikováno v:
Retrovirology
Retrovirology, Vol 8, Iss Suppl 1, p A125 (2011)
Retrovirology, Vol 8, Iss Suppl 1, p A125 (2011)
Human T-cell Leukemia Virus type-1 (HTLV-1) is highly immunogenic and has low variability so tight regulation of its expression is essential for virus maintenance in vivo. HTLV-1 replication is positively regulated by Tax and Rex, and negatively by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f07ad5cae59e0c88120f21ce57782bd0