Výsledky vyhledávání - "Uma Mudunuru"

Data from Combination of Pan-Histone Deacetylase Inhibitor and Autophagy Inhibitor Exerts Superior Efficacy against Triple-Negative Human Breast Cancer Cells

Autor: Kapil N. Bhalla, Peter Atadja, Kyungsoo Ha, Stacey L. Hembruff, Jacqueline E. Smith, Lata Chauhan, Sreedhar Venkannagari, Uma Mudunuru, Warren Fiskus, Ramesh Balusu, Rekha Rao

Histone deacetylase (HDAC) inhibitors (HDI) induce endoplasmic reticulum (ER) stress and apoptosis, while promoting autophagy, which promotes cancer cell survival when apoptosis is compromised. Here, we determined the in vitro and in vivo activity of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ab82ed0996509c2bc9a07a7c3f5a3c5
https://doi.org/10.1158/1535-7163.c.6535620.v1

Zobrazit plný text záznamu

Supplementary Figures 1 - 5 from Superior Efficacy of a Combined Epigenetic Therapy against Human Mantle Cell Lymphoma Cells

Autor: Kapil Bhalla, Victor E. Marquez, Peter Atadja, Stacey L. Hembruff, Jacqueline E. Smith, Uma Mudunuru, Eduardo Sotomayor, Jianguo Tao, Siddhartha Ganguly, Ramesh Balusu, Rekha Rao, Warren Fiskus

PDF file, 659K, Supplemental Figure 1. Treatment with DZNep depletes expression of PRC2 proteins in MCL MO2058 and Z-138 cells. Supplemental Figure 2. Treatment with DZNep upregulates mRNA expression of EZH2 target genes in MCL cells.A-C. Supplementa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31faf36e68913de6e4a28cc8a85ac622
https://doi.org/10.1158/1078-0432.22446656.v1

Zobrazit plný text záznamu

Data from Superior Efficacy of a Combined Epigenetic Therapy against Human Mantle Cell Lymphoma Cells

Purpose: A deregulated epigenome contributes to the transformed phenotype of mantle cell lymphoma (MCL). This involves activity of the polycomb repressive complex (PRC) 2, containing three core proteins, EZH2, SUZ12, and EED, in which the SET domain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e23f1be96c20029bb038751d1fb597c
https://doi.org/10.1158/1078-0432.c.6520814

Zobrazit plný text záznamu

The establishment of resident memory B cells in the lung requires local antigen encounter

Autor: Beth A. Graf, Frances E. Lund, Michael D. Schultz, S. Rameeza Allie, Uma Mudunuru, John E. Bradley, Troy D. Randall

Publikováno v: Nature immunology

Memory B cells are found in lymphoid and non-lymphoid tissues, suggesting that some may be tissue-resident cells. Here we show that pulmonary influenza infection elicited lung-resident memory B cells (BRM cells) that were phenotypically and functiona

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3759d0ffd346806e924aa215ae308bd3
https://doi.org/10.1038/s41590-018-0260-6

Zobrazit plný text záznamu

Superior Efficacy of a Combined Epigenetic Therapy against Human Mantle Cell Lymphoma Cells

Autor: Stacey Hembruff, Siddhartha Ganguly, Peter Atadja, Eduardo M. Sotomayor, Kapil N. Bhalla, Victor E. Marquez, Ramesh Balusu, Warren Fiskus, Jacqueline E. Smith, Rekha Rao, Jianguo Tao, Uma Mudunuru

Publikováno v: Clinical Cancer Research. 18:6227-6238

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c2af9cf01e79f780015cfd13ca7ab37
https://doi.org/10.1158/1078-0432.ccr-12-0873

Zobrazit plný text záznamu

VAT-associated ST2+Tregs from omentum support tolerance to peripheral tumors

Autor: Selene Meza-Perez, Aaron Silva-Sanchez, Maria de la Luz Garcia-Hernandez, Uma Mudunuru, Thomas S. Simpler, Troy D. Randall

Publikováno v: The Journal of Immunology. 198:155.8-155.8

Tumor metastasis to theomentum is associated with poor clinical outcomes. Although the omentum hasimmune function due to the activities of milky spots, the role of this organ inanti-tumor immunity has not been completely described. By implanting tumo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d1c7bc1e8031e87d18b04d4256d1449
https://doi.org/10.4049/jimmunol.198.supp.155.8

Zobrazit plný text záznamu

Identification of antigen-specific, lung resident memory B cells after influenza infection

Autor: S Rameeza Allie, John E Bradley, Uma Mudunuru, Troy D. Randall

Publikováno v: The Journal of Immunology. 198:153.19-153.19

B cells display phenotypic and functional heterogeneity in multiple anatomical locations following vaccination or infection. Influenza-specific memory B cells (Flu+BMEM cells) are found in both lymphoid tissues and lung. It is unclear whether these c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::55a36f1d21361e05382885432b1c3bc3
https://doi.org/10.4049/jimmunol.198.supp.153.19

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání