Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Uma Gayathri Kamakolanu"'
Autor:
Nurulain T. Zaveri, Michele Morari, Dennis Yasuda, Clarissa Anna Pisanò, Alberto Brugnoli, Matteo Marti, Uma Gayathri Kamakolanu, Michael E Meyer, Daniela Mercatelli, Willma E. Polgar
Publikováno v:
Journal of medicinal chemistry. 63(5)
A novel series of C(3)-substituted piperdinylindoles were developed as nociceptin opioid receptor (NOP) partial agonists to explore a pharmacological hypothesis that NOP partial agonists would afford a dual pharmacological action of attenuating Parki
Autor:
Anna Rizzi, Remo Guerrini, Uma Gayathri Kamakolanu, Federica Ferrari, Nurulain T. Zaveri, V. Blair Journigan, Laila Asth, Chiara Ruzza, Maria Camilla Cerlesi, Michael E Meyer, Davide Malfacini, Dennis Yasuda, Girolamo Calo, Elaine C. Gavioli, Willma E. Polgar
Nociceptin/Orphanin FQ (N/OFQ) regulates several biological functions via selective activation of the N/OFQ receptor (NOP). In this study novel nonpeptide NOP ligands were characterized in vitro in receptor binding and [35S]GTPγS stimulated binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea71250444d3a4152a8803393bd65756
https://europepmc.org/articles/PMC5555400/
https://europepmc.org/articles/PMC5555400/