Výsledky vyhledávání - "Uma Chippada-Venkata"

Constructing Bayesian networks by integrating gene expression and copy number data identifies NLGN4Y as a novel regulator of prostate cancer progression

Autor: William Oh, Jun Zhu, Li Wang, Xudong Dai, Uma Chippada-Venkata, Yixuan Gong

Publikováno v: Oncotarget

// Yixuan Gong 1, * , Li Wang 2, 3, * , Uma Chippada-Venkata 1 , Xudong Dai 2, 3 , William K. Oh 1 , Jun Zhu 1, 2, 3 1 The Tisch Cancer Institute, Division of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265e0170db53289ea3ec9a833f42e704
http://europepmc.org/articles/PMC5356583

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The antidiabetic compound 2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione, isolated from averrhoa carambola L., demonstrates significant antitumor potential against human breast cancer cells

Autor: Eric Vick, Hyo Park, Yixuan Gong, Qingwei Wen, Ying Gao, Uma Chippada-Venkata, Elliot Altman, Nadin Marwan Almosnid, Renbin Huang, Najlaa Abdulrhman Hosain, Anthony L. Farone

Publikováno v: Oncotarget

// Ying Gao 1 , Renbin Huang 2 , Yixuan Gong 3 , Hyo Sim Park 1 , Qingwei Wen 2 , Nadin Marwan Almosnid 1 , Uma D. Chippada-Venkata 3 , Najlaa Abdulrhman Hosain 1 , Eric Vick 1 , Anthony Farone 1 and Elliot Altman 1 1 Tennessee Center for Botanical M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1c34786f4f32b486aea17df1d019b7
https://doi.org/10.18632/oncotarget.4475

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Elevated circulating tissue inhibitor of metalloproteinase 1 (TIMP-1) levels are associated with neuroendocrine differentiation in castration resistant prostate cancer

Autor: Matthew D. Galsky, Yixuan Gong, William Oh, Jiaoti Huang, Uma Chippada-Venkata

Publikováno v: The Prostate. 75:616-627

BACKGROUND. Tissue inhibitor of metalloproteinase-1 (TIMP-1) is a 28.5kDa secreted glycoprotein that inhibits matrix metalloproteinase (MMP) activity. Our group has previously shown that elevated plasma TIMP-1 levels predict poor survival in metastat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cdec905c5be0ee927d7f18623efbcad0
https://doi.org/10.1002/pros.22945

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Roles of Matrix Metalloproteinases and Their Natural Inhibitors in Prostate Cancer Progression

Autor: William Oh, Uma Chippada-Venkata, Yixuan Gong

Publikováno v: Cancers, Vol 6, Iss 3, Pp 1298-1327 (2014)
Cancers

Matrix metalloproteinases (MMPs), a group of zinc-dependent endopeptidases involved in the degradation of the extracellular matrix, play an important role in tissue remodeling associated with various physiological processes such as morphogenesis, ang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31800820e8ac53bc2dd774b84e2c2f8a
http://www.mdpi.com/2072-6694/6/3/1298

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Generation of Prostate Cancer Patient Derived Xenograft Models from Circulating Tumor Cells

Autor: Estrelania S, Williams, Veronica, Rodriguez-Bravo, Veronica, Rodriquez-Bravo, Uma, Chippada-Venkata, Janis, De Ia Iglesia-Vicente, Yixuan, Gong, Matthew, Galsky, William, Oh, Carlos, Cordon-Cardo, Josep, Domingo-Domenech

Publikováno v: Journal of Visualized Experiments.

Patient derived xenograft (PDX) models are gaining popularity in cancer research and are used for preclinical drug evaluation, biomarker identification, biologic studies, and personalized medicine strategies. Circulating tumor cells (CTC) play a crit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f909a03bb9fa78300631b011d231963b
https://doi.org/10.3791/53182-v

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A robust blood gene expression-based prognostic model for castration-resistant prostate cancer

Autor: William Oh, Yixuan Gong, Matthias Heck, Matthew D. Galsky, Roman Nawroth, Eric E. Schadt, Johann S. de Bono, Uma Chippada-Venkata, Li Wang, Margitta Retz, Che-Kai Tsao, David Olmos, Jun Zhu

Publikováno v: Repisalud
Instituto de Salud Carlos III (ISCIII)
BMC Medicine

Castration-resistant prostate cancer (CRPC) is associated with wide variations in survival. Recent studies of whole blood mRNA expression-based biomarkers strongly predicted survival but the genes used in these biomarker models were non-overlapping a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20bece3b92e99eda2d9a7400a20bd626
https://hdl.handle.net/20.500.12105/10315

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Abstract 1098: TIMP-1: A potential biomarker of neuroendocrine differentiation in metastatic castration-resistant prostate cancer (mCRPC)

Autor: Jiaoti Huang, Xudong Dai, Matthew D. Galsky, Uma Chippada-Venkata, Yixuan Gong

Publikováno v: Cancer Research. 74:1098-1098

BACKGROUND: Tissue inhibitor of metalloproteinases-1 (TIMP-1) is a 28.5 kDa secreted glycoprotein that inhibits matrix metalloproteinase (MMP) activity. Recent studies have demonstrated that TIMP-1 promotes tumor growth in an MMP-independent manner.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::82ae3c12259d189861bdeec22b4cc44a
https://doi.org/10.1158/1538-7445.am2014-1098

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Impact of chemotherapy alone, and chemotherapy plus ipilimumab, on circulating immune cells in patients with metastatic bladder cancer

Autor: Nina Bhardwaj, William Oh, Hahn Noah, Manishkumar Patel, Jun Zhu, Sacha Gnjatic, Guru Sonpavde, Ralph J. Hauke, Mark T. Fleming, Costantine Albany, Seunghee Kim-Schulze, Li Wang, Miriam Merad, Matthew D. Galsky, Uma Chippada-Venkata, Alexander Starodub, Przemyslaw Twardowski, Jingjing Qi

Publikováno v: Journal for Immunotherapy of Cancer

Meeting abstracts Metastatic bladder cancer (MBC) is a relatively chemosensitive neoplasm yet response durations are generally short-lived. Recently, immune checkpoint blockade has demonstrated unparalleled activity in heavily pre-treated patients (p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3232095cee3ceb0082ed15661c8c3c4c
http://europepmc.org/articles/PMC4649313

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Impact of gemcitabine + cisplatin + ipilimumab on circulating immune cells in patients (pts) with metastatic urothelial cancer (mUC)

Autor: Ralph J. Hauke, Przemyslaw Twardowski, Nina Bhardwaj, Costantine Albany, Miriam Merad, Matthew D. Galsky, William Oh, Uma Chippada-Venkata, Alexander Starodub, Sacha Gnjatic, Guru Sonpavde, Noah M. Hahn, Mark D. Fleming, Seunghee Kim-Schulze

Publikováno v: Journal of Clinical Oncology. 33:4586-4586

4586 Background: Immune checkpoint blockade may play a role in the treatment of mUC. However, the role of CTLA4 blockade, the impact of chemotherapy on immune cell populations, and the optimal appr...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ae3535d44ac251a13d6b31de206ad91
https://doi.org/10.1200/jco.2015.33.15_suppl.4586

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Influence of prostate cancer disease state and therapeutic selection on peripheral whole-blood RNA signature

Autor: Che-Kai Tsao, Matthias Heck, Matthew D. Galsky, Li Wang, Uma Chippada-Venkata, Jun Zhu, William Oh, Yixuan Gong, Bobby Chi-Hung Liaw

Publikováno v: Journal of Clinical Oncology. 33:166-166

166 Background: Prostate cancer is a heterogeneous disease with differences in tumor stromal interactions contributing to variability in treatment response and outcome. Gene expression of peripheral blood cells is altered by interactions with neoplas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba84ef59022ee028f06ea0ef1b6bf107
https://doi.org/10.1200/jco.2015.33.7_suppl.166

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