Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Uma A, Mukherjee"'
Autor:
Hilary K Siddall, Derek M Yellon, Sang-Bing Ong, Uma A Mukherjee, Niall Burke, Andrew R Hall, Plamena R Angelova, Marthe H R Ludtmann, Emma Deas, Sean M Davidson, Mihaela M Mocanu, Derek J Hausenloy
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62400 (2013)
Mutations in PTEN inducible kinase-1 (PINK1) induce mitochondrial dysfunction in dopaminergic neurons resulting in an inherited form of Parkinson's disease. Although PINK1 is present in the heart its exact role there is unclear. We hypothesized that
Externí odkaz:
https://doaj.org/article/dde8266e1e2f4f309d4fe3816f92898f
Autor:
Hilary K. Siddall, Derek M. Yellon, Sang-Bing Ong, Uma A. Mukherjee, Niall Burke, Andrew R. Hall, Plamena R. Angelova, Marthe H. R. Ludtmann, Emma Deas, Sean M. Davidson, Mihaela M. Mocanu, Derek J. Hausenloy
Publikováno v:
PLoS ONE, Vol 8, Iss 6 (2013)
Externí odkaz:
https://doaj.org/article/c75a8916fe1b4752b8347e6dbf0e222e
Publikováno v:
Pharmacology & Therapeutics
Ischemic heart disease (IHD) is the leading cause of death and disability worldwide. Therefore, novel therapeutic targets for protecting the heart against acute ischemia/reperfusion injury (IRI) are required to attenuate cardiomyocyte death, preserve
Autor:
Marthe H.R. Ludtmann, Plamena R. Angelova, Hilary K. Siddall, Sang Bing Ong, Sean M. Davidson, Andrew R. Hall, Niall Burke, Derek J. Hausenloy, Derek M. Yellon, Emma Deas, Mihaela M. Mocanu, Uma A. Mukherjee
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62400 (2013)
PLoS ONE
PLoS ONE
Objectives Mutations in PTEN inducible kinase-1 (PINK1) induce mitochondrial dysfunction in dopaminergic neurons resulting in an inherited form of Parkinson’s disease. Although PINK1 is present in the heart its exact role there is unclear. We hypot
Autor:
Niall Burke, Marthe H.R. Ludtmann, Mihaela M. Mocanu, Sean M. Davidson, Derek M. Yellon, Uma A. Mukherjee, Andrew R. Hall, Sang Bing Ong, Emma Deas, Plamena R. Angelova, Hilary K. Siddall, Derek J. Hausenloy
Publikováno v:
PLoS ONE, Vol 8, Iss 6 (2013)
PLoS ONE
PLoS ONE
There were errors in the order of labels and legends. The labels and legends for Figures 5 and 6 were switched. The label and legend that appear under Figure 5 belong under Figure 6, and the label and legend that appear under Figure 6 belong under Fi
Publikováno v:
Heart. 97:e8-e8
Rationale Mutations in the DJ-1 gene are a cause of familial Parkinson9s disease. Dopaminergic neurones deficient in DJ-1 have impaired mitochondrial function and are more susceptible to oxidative stress. DJ-1 is present in the heart but its role the