Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ulysses Tsz Fung Lam"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The detection of cancer-driving mutations is important for understanding cancer pathology and therapeutics development. Prediction tools have been created to streamline the computation process. However, most tools available have heterogeneou
Externí odkaz:
https://doaj.org/article/90b54d1762c04004b27a8eb2dea346a9
Publikováno v:
Epigenetics & Chromatin, Vol 15, Iss 1, Pp 1-20 (2022)
Abstract The methylation of histone H3 at lysine 36 (H3K36me) is essential for maintaining genomic stability. Indeed, this methylation mark is essential for proper transcription, recombination, and DNA damage response. Loss- and gain-of-function muta
Externí odkaz:
https://doaj.org/article/1a37bd7da96549a9b3ff57e883da97f1
Autor:
Kim Kiat Lim, Hwei Yee Teo, Yuan Yee Tan, Yi Bing Zeng, Ulysses Tsz Fung Lam, Mahesh Choolani, Ee Sin Chen
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 639 (2021)
Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the folate metabolic pathway, and its loss of function through polymorphisms is often associated with human conditions, including cancer, congenital heart disease, and Down syndrome. MTHF
Externí odkaz:
https://doaj.org/article/f040bb4ec7eb4cfe9987d89581ce912f
Publikováno v:
Epigeneticschromatin. 15(1)
The methylation of histone H3 at lysine 36 (H3K36me) is essential for maintaining genomic stability. Indeed, this methylation mark is essential for proper transcription, recombination, and DNA damage response. Loss- and gain-of-function mutations in
Autor:
Ulysses Tsz Fung, Lam, Ee Sin, Chen
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 144:106155
Epigenetic dysregulation is an important contributor to carcinogenesis. This is not surprising, as chromatin-genomic DNA organized around structural histone scaffolding-serves as the template on which occurs essential nuclear processes, such as trans
Autor:
Ulysses Tsz-Fung Lam, Thi Thuy Trang Nguyen, Raechell Raechell, Jay Yang, Harry Singer, Ee Sin Chen
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2829 (2023)
Edge effect denotes better growth of microbial organisms situated at the edge of the solid agar media. Although the precise reason underlying edge effect is unresolved, it is generally attributed to greater nutrient availability with less competing n
Externí odkaz:
https://doaj.org/article/818ce6701fa243039489ec4e4d0cd12c