Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ulysses Tsz Fung Lam"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The detection of cancer-driving mutations is important for understanding cancer pathology and therapeutics development. Prediction tools have been created to streamline the computation process. However, most tools available have heterogeneou
Externí odkaz:
https://doaj.org/article/90b54d1762c04004b27a8eb2dea346a9
Publikováno v:
Epigenetics & Chromatin, Vol 15, Iss 1, Pp 1-20 (2022)
Abstract The methylation of histone H3 at lysine 36 (H3K36me) is essential for maintaining genomic stability. Indeed, this methylation mark is essential for proper transcription, recombination, and DNA damage response. Loss- and gain-of-function muta
Externí odkaz:
https://doaj.org/article/1a37bd7da96549a9b3ff57e883da97f1
Publikováno v:
Epigeneticschromatin. 15(1)
The methylation of histone H3 at lysine 36 (H3K36me) is essential for maintaining genomic stability. Indeed, this methylation mark is essential for proper transcription, recombination, and DNA damage response. Loss- and gain-of-function mutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f611315238f952e7875965efeb6f7fa6
https://pubmed.ncbi.nlm.nih.gov/35581654
https://pubmed.ncbi.nlm.nih.gov/35581654
Autor:
Kim Kiat Lim, Ee Sin Chen, Yi Bing Zeng, Hwei Yee Teo, Yuan Yee Tan, Ulysses Tsz Fung Lam, Mahesh Choolani
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 639, p 639 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 2
International Journal of Molecular Sciences
Volume 22
Issue 2
Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the folate metabolic pathway, and its loss of function through polymorphisms is often associated with human conditions, including cancer, congenital heart disease, and Down syndrome. MTHF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::955da042533b7072828383bb2ecd0f8e
https://www.mdpi.com/1422-0067/22/2/639
https://www.mdpi.com/1422-0067/22/2/639
Autor:
Ulysses Tsz Fung, Lam, Ee Sin, Chen
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 144:106155
Epigenetic dysregulation is an important contributor to carcinogenesis. This is not surprising, as chromatin-genomic DNA organized around structural histone scaffolding-serves as the template on which occurs essential nuclear processes, such as trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88019602daca4f3d3e1e69daeee9718a
https://doi.org/10.1016/j.biocel.2021.106155
https://doi.org/10.1016/j.biocel.2021.106155
Autor:
Ulysses Tsz-Fung Lam, Thi Thuy Trang Nguyen, Raechell Raechell, Jay Yang, Harry Singer, Ee Sin Chen
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2829 (2023)
Edge effect denotes better growth of microbial organisms situated at the edge of the solid agar media. Although the precise reason underlying edge effect is unresolved, it is generally attributed to greater nutrient availability with less competing n
Externí odkaz:
https://doaj.org/article/818ce6701fa243039489ec4e4d0cd12c