Assessment of malaria transmission intensity and insecticide resistance mechanisms in three rural areas of the Moyen Ogooué Province of Gabon

Autor: Stravensky Térence Boussougou-Sambe, Tamirat Gebru Woldearegai, Ange Gatien Doumba-Ndalembouly, Barclaye Ngossanga, Romuald Beh Mba, Jean Ronald Edoa, Jeannot Fréjus Zinsou, Yabo Josiane Honkpehedji, Ulysse Ateba Ngoa, Jean Claude Dejon-Agobé, Steffen Borrmann, Peter G. Kremsner, Benjamin Mordmüller, Ayôla A. Adegnika

Publikováno v: Parasites & Vectors, Vol 15, Iss 1, Pp 1-13 (2022)

Abstract Background Vector control is considered to be the most successful component of malaria prevention programs and a major contributor to the reduction of malaria incidence over the last two decades. However, the success of this strategy is thre

Externí odkaz: https://doaj.org/article/1beebe6e5a94437dbc9ca14944a9319f

Exploratory analysis of the effect of helminth infection on the immunogenicity and efficacy of the asexual blood-stage malaria vaccine candidate GMZ2.

Autor: Odilon Nouatin, Juliana Boex Mengue, Jean Claude Dejon-Agobé, Rolf Fendel, Javier Ibáñez, Ulysse Ateba Ngoa, Jean Ronald Edoa, Bayodé Roméo Adégbité, Yabo Josiane Honkpéhédji, Jeannot Fréjus Zinsou, Aurore Bouyoukou Hounkpatin, Kabirou Moutairou, Andreas Homoet, Meral Esen, Andrea Kreidenweiss, Stephen L Hoffman, Michael Theisen, Adrian J F Luty, Bertrand Lell, Selidji Todagbe Agnandji, Ghyslain Mombo-Ngoma, Michael Ramharter, Peter Kremsner, Benjamin Mordmüller, Ayôla Akim Adegnika

Publikováno v: PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009361 (2021)

BackgroundHelminths can modulate the host immune response to Plasmodium falciparum and can therefore affect the risk of clinical malaria. We assessed here the effect of helminth infections on both the immunogenicity and efficacy of the GMZ2 malaria v

Externí odkaz: https://doaj.org/article/bb9e94c7a35042c8863884855ee8d7a3

Enhanced laboratory capacity development: a boost for effective tuberculosis control in resource-limited settings

Autor: Abraham Sunday Alabi, Afsatou Ndama Traoré, Marguerite Massinga Loembe, Ulysse Ateba-Ngoa, Matthias Frank, Ayola Akim Adegnika, Bertrand Lell, Jocelyn Mahoumbou, Carsten Köhler, Peter Gottfried Kremsner, Martin Peter Grobusch

Publikováno v: International Journal of Infectious Diseases, Vol 56, Iss C, Pp 81-84 (2017)

Both routine and research tuberculosis (TB) laboratory capacity urgently need to be expanded in large parts of Sub-Saharan Africa. In 2009, the Centre de Recherches Médicales de Lambaréné (CERMEL) took a strategic decision to expand its activities

Externí odkaz: https://doaj.org/article/91b9d8d1eb484d0ea07681d3c73f0c4f

Differences in innate cytokine responses between European and African children.

Autor: Lucja A Labuda, Sanne E de Jong, Lynn Meurs, Abena S Amoah, Moustapha Mbow, Ulysse Ateba-Ngoa, Alwin J van der Ham, André C Knulst, Maria Yazdanbakhsh, Ayola A Adegnika

Publikováno v: PLoS ONE, Vol 9, Iss 4, p e95241 (2014)

Although differences in immunological responses between populations have been found in terms of vaccine efficacy, immune responses to infections and prevalence of chronic inflammatory diseases, the mechanisms responsible for these differences are not

Externí odkaz: https://doaj.org/article/eb20e806408548b7b673ca2b403aea12

Extended follow-up of children in a phase2b trial of the GMZ2 malaria vaccine

Autor: Peter G. Kremsner, Sodiomon B. Sirima, Paul Milligan, Fareed K. N. Arthur, Sylvester Dassah, Benjamin Mordmüller, Donnie Mategula, Michael Theisen, Clare Flach, Bright Adu, Peter Bang, Ulysse Ateba Ngoa, Benedicta A. Mensah, Frank Atuguba, Mark Kaddumukasa

Publikováno v: Dassah, S, Adu, B, Sirima, S B, Mordmüller, B, Ngoa, U A, Atuguba, F, Arthur, F K N, Mensah, B A, Kaddumukasa, M, Bang, P, Kremsner, P G, Mategula, D, Flach, C, Milligan, P & Theisen, M 2021, ' Extended follow-up of children in a phase2b trial of the GMZ2 malaria vaccine ', Vaccine, vol. 39, no. 31, pp. 4314-4319 . https://doi.org/10.1016/j.vaccine.2021.06.024

BACKGROUND: The GMZ2/alum candidate malaria vaccine had an efficacy of 14% (95% confidence interval [CI]: 3.6%, 23%) against clinical malaria over 6 months of follow-up in a phase2b multicentre trial in children 1-5 years of age. Here we report the e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce98f123ff6d3e2de49578952eeeb501
https://curis.ku.dk/portal/da/publications/extended-followup-of-children-in-a-phase2b-trial-of-the-gmz2-malaria-vaccine(c476a403-6050-436c-a6d8-0c2d7c13bda2).html