Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Ulyana A. Boyarskikh"'
Autor:
Ulyana A. Boyarskikh, L. F. Gulyaeva, A. M. Avdalyan, A. A. Kechin, E. A. Khrapov, D. G. Lazareva, N. E. Kushlinskii, A. Melkonyan, A. Arakelyan, Maxim Leonidovich Filipenko
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Objective: Mutations in TP53 lead to loss of function (LOF) or gain of function (GOF) of the corresponding protein p53 and produce a different effect on the tumor. Our goal was to determine the spectrum of somatic TP53 variants in BRCA1/2 associated
Externí odkaz:
https://doaj.org/article/6212bc92777a484e94d370ba926d020e
Autor:
Igor P. Oscorbin, Ekaterina A. Belousova, Aleksandr I. Zakabunin, Ulyana A. Boyarskikh, Maksim L. Filipenko
Publikováno v:
BioTechniques, Vol 61, Iss 1, Pp 20-25 (2016)
Real-time or quantitative loop-mediated isothermal amplification (qLAMP) is a promising technique for the accurate detection of pathogens in organisms and the environment. Here we present a comparative study of the performance of six fluorescent inte
Externí odkaz:
https://doaj.org/article/473069cf09dd49709d5963c0b3aa78d6
Autor:
Sergey G. Scherbak, Ulyana A. Boyarskikh, Darya Boldyreva, Svetlana V. Apalko, Andrey Kechin, Maxim L. Filipenko, Lidia Kaftyreva, Maria Makarova, Viktoriya Borobova, Nikolay Mosyakin
Publikováno v:
The Journal of Biochemistry. 170:675-681
Next-generation sequencing (NGS)-library preparation for whole-genome sequencing (WGS) starts with DNA fragmentation, and sonication is a physical approach used most often due to its simplicity and reproducibility. However, the commercially available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9e7b77c720f8c6ddc710940726c9c5
https://doi.org/10.1093/jb/mvab089
https://doi.org/10.1093/jb/mvab089
Autor:
Igor P. Oscorbin, Maria A. Smertina, Ksenia A. Pronyaeva, Mikhail E. Voskoboev, Ulyana A. Boyarskikh, Andrey A. Kechin, Irina A. Demidova, Maxim L. Filipenko
Publikováno v:
Cancers; Volume 14; Issue 6; Pages: 1458
Non-small-cell lung cancer (NSCLC), a subtype of lung cancer, remains one of the most common tumors with a high mortality and morbidity rate. Numerous targeted drugs were implemented or are now developed for the treatment of NSCLC. Two genes, HER2 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f363f2322c290dedaf8dd067aa6b96
Autor:
T. V. Kekeeva, Svetlana Kazakova, Sergey Subbotin, Maxim L. Filipenko, Evgeniy Khrapov, Olga V. Mishukova, Alexander S Tanas, Ulyana A. Boyarskikh, Andrey Kechin, I. A. Demidova, Anastasia Zhevlova, Alexey Barinov
Pathogenic mutations in BRCA1 and BRCA2 genes are essential biomarkers of an increased breast and ovarian cancer risk and tumor sensitivity to poly ADP ribose (PARP) inhibitors. In many countries, their detection includes patient prescreening with qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dd0067de1d9fd9998460d97409ac993
https://doi.org/10.1101/2021.07.22.21260831
https://doi.org/10.1101/2021.07.22.21260831
Walking pathways with positive feedback loops reveal DNA methylation biomarkers of colorectal cancer
Autor:
Leonid S. Leskov, Alexander E. Kel, Manel Esteller, Olga V. Kel-Margoulis, Ulyana A. Boyarskikh, Sebastian Moran, Philip Stegmaier, Daria Stelmashenko, Anna Martínez-Cardús, Nikita Mandrik, Jeannette Koschmann, Edgar Wingender, Andrey Sokolov, Fedor A. Kolpakov, Ivan S. Yevshin, Mathias Krull, Maxim L. Filipenko
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S4, Pp 1-20 (2019)
BMC Bioinformatics
BMC Bioinformatics
Background The search for molecular biomarkers of early-onset colorectal cancer (CRC) is an important but still quite challenging and unsolved task. Detection of CpG methylation in human DNA obtained from blood or stool has been proposed as a promisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d42cc2870eb3549008c9452f0b637c
http://link.springer.com/article/10.1186/s12859-019-2687-7
http://link.springer.com/article/10.1186/s12859-019-2687-7
Autor:
Maxim L. Filipenko, Evgeniy Khrapov, Sergey Subbotin, Ulyana A. Boyarskikh, Andrey Kechin, Viktoria Borobova
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 12, p e1008468 (2020)
PLoS Computational Biology
PLoS Computational Biology
Multiplex polymerase chain reaction (PCR) has multiple applications in molecular biology, including developing new targeted next-generation sequencing (NGS) panels. We present NGS-PrimerPlex, an efficient and versatile command-line application that d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c8d87377e92e93ed20a7176a01c328
https://doaj.org/article/78a6fc1d623f40cfb563205ab88aea94
https://doaj.org/article/78a6fc1d623f40cfb563205ab88aea94
Autor:
Ulyana A. Boyarskikh, L. F. Gulyaeva, A. M. Avdalyan, A. A. Kechin, E. A. Khrapov, D. G. Lazareva, N. E. Kushlinskii, A. Melkonyan, A. Arakelyan, Maxim Leonidovich Filipenko
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology
Frontiers in Oncology
Objective: Mutations in TP53 lead to loss of function (LOF) or gain of function (GOF) of the corresponding protein p53 and produce a different effect on the tumor. Our goal was to determine the spectrum of somatic TP53 variants in BRCA1/2 associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5303e0ffaea3533b9a88878049420258
https://pubmed.ncbi.nlm.nih.gov/32766142
https://pubmed.ncbi.nlm.nih.gov/32766142
Autor:
Maksim L. Filipenko, N. E. Kushlinskii, A.N. Shirshova, D. A. Shamovskaya, Ulyana A. Boyarskikh
Publikováno v:
MethodsX, Vol 5, Iss, Pp 737-743 (2018)
MethodsX
MethodsX
MicroRNA extraction is an essential procedure when discovering MicroRNA-based biomarkers and approaches. Here we describe a new method for microRNA isolation from human blood plasma, based on isopropanol precipitation from the one-phase lysate. We de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66545bca9eb645bcbeb3e6bb2f298d6
http://www.sciencedirect.com/science/article/pii/S2215016118301092
http://www.sciencedirect.com/science/article/pii/S2215016118301092
Autor:
Igor P. Oscorbin, Maksim L. Filipenko, Ulyana A. Boyarskikh, A. I. Zakabunin, Ekaterina A. Belousova, Evgeny A. Khrapov
Publikováno v:
Nucleic Acids Research
At the moment, one of the actual trends in medical diagnostics is a development of methods for practical applications such as point-of-care testing, POCT or research tools, for example, whole genome amplification, WGA. All the techniques are based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38fd7dad76b5c0e788036dcdffeca419
https://doi.org/10.1093/nar/gkx645
https://doi.org/10.1093/nar/gkx645