Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Ulus Atasoy"'
Autor:
Yixuan Liao, Raymond G. Cavalcante, Jonathan B. Waller, Furong Deng, Anne M. Scruggs, Yvonne J. Huang, Ulus Atasoy, Yahong Chen, Steven K. Huang
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background DNA methylation plays a critical role in asthma development, but differences in DNA methylation among adults with varying asthma severity are less well-defined. Objective To examine how DNA methylomic patterns differ among adults
Externí odkaz:
https://doaj.org/article/6ce6098a296842a6a00d85c4828f0aed
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
After antigen and/or different cytokine stimulation, CD4+ T cells activated and differentiated into distinct T helper (Th) cells via differential T cell signaling pathways. Transcriptional regulation of the activation and differentiation of naïve CD
Externí odkaz:
https://doaj.org/article/7cafad09550a40cfb1b4acf1de04fd7b
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0129321 (2015)
Due to poor correlation between steady state mRNA levels and protein product, purely transcriptomic profiling methods may miss genes posttranscriptionally regulated by RNA binding proteins (RBPs) and microRNAs (miRNAs). RNA immunoprecipitation (RIP)
Externí odkaz:
https://doaj.org/article/09bf98a11dcc4e42b537eaf0ab308019
Autor:
Rebecca Haffner-Krausz, Noam Kadouri, Jan Dobeš, Eirik Bratland, Golda M. Damari, Yael Goldfarb, Uku Haljasorg, Cristina Peligero-Cruz, Eystein S. Husebye, Bareket Dassa, Amund Holte Berger, Tal Givony, Bergithe E. Oftedal, Ziv Porat, Martina M. Erichsen, Ulus Atasoy, Dena Leshkowitz, Itay Zalayat, Shir Nevo, Yael Gruper, Jakub Abramson, Ayelet Avin, Adi Ulman, Yael Kuperman, Shifra Ben-Dor
Publikováno v:
Journal of Experimental Medicine. 218
The autoimmune regulator (AIRE) is essential for the establishment of central tolerance and prevention of autoimmunity. Interestingly, different AIRE mutations cause autoimmunity in either recessive or dominant-negative manners. Using engineered mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa389fbe83884fdc0eaec1c83101d67f
https://doi.org/10.1084/jem.20201076
https://doi.org/10.1084/jem.20201076
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
After antigen and/or different cytokine stimulation, CD4+ T cells activated and differentiated into distinct T helper (Th) cells via differential T cell signaling pathways. Transcriptional regulation of the activation and differentiation of naïve CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81018eaa6cf40ad540d83cb6f07e895b
Autor:
Fatemeh Fattahi, Jason S Ellis, Michael Sylvester, Kristin Bahleda, Njira L Lugogo, Ulus Atasoy
Publikováno v:
The Journal of Immunology. 208:166.09-166.09
The RNA-binding protein HuR (elavl1) positively regulates the expression of its targets by increasing mRNA stability and translation. Th2 and Th17 related genes play critical roles in airway inflammation in both mouse and human. Using in vitro and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::914560c2293135d8a04339adb8ea4564
https://doi.org/10.4049/jimmunol.208.supp.166.09
https://doi.org/10.4049/jimmunol.208.supp.166.09
Publikováno v:
The Journal of Immunology. 208:44.11-44.11
The RNA-binding protein HuR (Elavl1) plays a critical role in T cell activation and function by regulating the stability and transport of its mRNA targets. To study the role of HuR in regulatory T cell (Treg) development and function, we generated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2a60e5884d9d7dd610149aaf08362c0
https://doi.org/10.4049/jimmunol.208.supp.44.11
https://doi.org/10.4049/jimmunol.208.supp.44.11
Autor:
Fatemeh Fattahi, Jason Ellis, Michael Sylvester, Kristin Bahleda, Samuel Hietanen, Njira Lugogo, Ulus Atasoy
Publikováno v:
Journal of Allergy and Clinical Immunology. 149:AB323
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46ec197dd40a758ea0f3e93437cb1320
https://doi.org/10.1016/j.jaci.2021.12.035
https://doi.org/10.1016/j.jaci.2021.12.035
Autor:
Myriam Gorospe, Suzanne E. Ridenhour, Hao Zhou, Wade Davis, Patsharaporn Techasintana, Ulus Atasoy, Joseph D. Magee, Xiaoxia Li, Marcia L. Hart, Jason S. Ellis, Paul L. Fox, Peng Yao, Maryln S. Whitney, Craig L. Franklin, Jennifer L. Martindale, Jacqueline J. Glascock, Matthew M. Gubin
Publikováno v:
ImmunoHorizons. 1:109-123
Posttranscriptional gene regulation by RNA-binding proteins, such as HuR (elavl1), fine-tune gene expression in T cells, leading to powerful effects on immune responses. HuR can stabilize target mRNAs and/or promote translation by interacting with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::676eb12302c8bc8e7a3a6e6e7505971b
https://doi.org/10.4049/immunohorizons.1700017
https://doi.org/10.4049/immunohorizons.1700017
Autor:
Fatemeh Fattahi, Jason S Ellis, Michael Sylvester, Kristin Bahelda, Sam Hietanen, Luis O Correa, Njira Lugogo, Ulus Atasoy
Publikováno v:
The Journal of Immunology. 206:53.12-53.12
RNA-binding protein human antigen R (HuR) is a master regulator of gene expression in human pathophysiology. Our animal studies in the past showed multiple critical roles for HuR in regulating proinflammatory markers in CD4+ T cells. We hypothesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92c19cae03c515ed38a9284cbb73d4f6
https://doi.org/10.4049/jimmunol.206.supp.53.12
https://doi.org/10.4049/jimmunol.206.supp.53.12