Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ulupi S Jhala"'
Autor:
Laura Bordone, Maria Carla Motta, Frederic Picard, Ashley Robinson, Ulupi S Jhala, Javier Apfeld, Thomas McDonagh, Madeleine Lemieux, Michael McBurney, Akos Szilvasi, Erin J Easlon, Su-Ju Lin, Leonard Guarente
Publikováno v:
PLoS Biology, Vol 13, Iss 12, p e1002346 (2015)
Externí odkaz:
https://doaj.org/article/53a2384884e14d228a202f334a7a8de2
Autor:
Laura Bordone, Maria Carla Motta, Frederic Picard, Ashley Robinson, Ulupi S Jhala, Javier Apfeld, Thomas McDonagh, Madeleine Lemieux, Michael McBurney, Akos Szilvasi, Erin J Easlon, Su-Ju Lin, Leonard Guarente
Publikováno v:
PLoS Biology, Vol 4, Iss 9 (2006)
Externí odkaz:
https://doaj.org/article/cdadccbff69a49a8b027e8e3bad2f5aa
Autor:
Laura Bordone, Maria Carla Motta, Frederic Picard, Ashley Robinson, Ulupi S Jhala, Javier Apfeld, Thomas McDonagh, Madeleine Lemieux, Michael McBurney, Akos Szilvasi, Erin J Easlon, Su-Ju Lin, Leonard Guarente
Publikováno v:
PLoS Biology, Vol 4, Iss 2, p e31 (2006)
Sir2 and insulin/IGF-1 are the major pathways that impinge upon aging in lower organisms. In Caenorhabditis elegans a possible genetic link between Sir2 and the insulin/IGF-1 pathway has been reported. Here we investigate such a link in mammals. We s
Externí odkaz:
https://doaj.org/article/4f48d2d275da44578e958920dcf5b1e2
Autor:
Nicholas K. Vinckier, Nisha A. Patel, Ryan J. Geusz, Allen Wang, Jinzhao Wang, Ileana Matta, Austin R. Harrington, Matthew Wortham, Nichole Wetton, Jianxun Wang, Ulupi S. Jhala, Michael G. Rosenfeld, Christopher W. Benner, Hung-Ping Shih, Maike Sander
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
How epigenetic regulation affects pancreatic development is unclear. Here, the authors show that the histone demethylase LSD1 regulates the epigenetic state of developmental enhancers during pancreatic specification and controls how these enhancers r
Externí odkaz:
https://doaj.org/article/219e2bb5225f43dcb77d228c096f4de8
Autor:
Matthew Wortham, Fenfen Liu, Austin R. Harrington, Johanna Y. Fleischman, Martina Wallace, Francesca Mulas, Medhavi Mallick, Nicholas K. Vinckier, Benjamin R. Cross, Joshua Chiou, Nisha A. Patel, Yinghui Sui, Carolyn McGrail, Yesl Jun, Gaowei Wang, Ulupi S. Jhala, Roland Schüle, Orian S. Shirihai, Mark O. Huising, Kyle J. Gaulton, Christian M. Metallo, Maike Sander
Publikováno v:
Journal of Clinical Investigation. 133
Adaptation of the islet β-cell insulin secretory response to changing insulin demand is critical for blood glucose homeostasis, yet the mechanisms underlying this adaptation are unknown. Here, we have shown that nutrient-stimulated histone acetylati
Signaling via IL1β and TLR4 receptors (IL1R-TLR4) plays a crucial role in cytokine and fatty acid-induced beta cell inflammation, in type 1 and type 2 diabetes respectively. IL1R-TLR4 share signaling mechanisms via a common, cytoplasmic, toll-like-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2137e3485ab7891cf4bd4b1c158aaee8
https://doi.org/10.1101/2022.10.09.511391
https://doi.org/10.1101/2022.10.09.511391
Publikováno v:
Journal of Biological Chemistry. :104803
Autor:
Hung Ping Shih, Allen Wang, Christopher Benner, Michael G. Rosenfeld, Matthew Wortham, Nicholas Vinckier, Ileana Matta, Ryan J Geusz, Jianxun Wang, Ulupi S. Jhala, Austin R. Harrington, Jinzhao Wang, Nichole Wetton, Nisha A. Patel, Maike Sander
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature communications, vol 11, iss 1
Nature Communications
Nature communications, vol 11, iss 1
Developmental progression depends on temporally defined changes in gene expression mediated by transient exposure of lineage intermediates to signals in the progenitor niche. To determine whether cell-intrinsic epigenetic mechanisms contribute to sig
Autor:
Wortham M, Cross Br, Harrington Ar, Maike Sander, Wallace M, Gaulton Kj, Furong Liu, Yinghui Sui, Christian M. Metallo, Francesca Mulas, Nikit Patel, Orian S. Shirihai, Mark O. Huising, Nicholas Vinckier, Fleischman Jy, Joshua Chiou, Ulupi S. Jhala
Adaptation of the islet β-cell insulin secretory response to changing insulin demand is critical for blood glucose homeostasis, yet the mechanisms underlying this adaptation are unknown. Here, we show that nutrient-stimulated histone acetylation pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e64f9fb974be35c4ed196ba535249ed8
Autor:
Jinzhao Wang, Christopher Benner, Allen Wang, Michael G. Rosenfeld, Jianxun Wang, Nicholas Vinckier, Ulupi S. Jhala, Hung-Ping Shih, Maike Sander, Nisha A. Patel
Developmental progression depends on temporally defined changes in gene expression mediated by transient exposure of lineage intermediates to signals in the progenitor niche. To identify a possible contribution of cell-intrinsic epigenetic mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::814bc99f9564e1f9a32870c4ab529ff3
https://doi.org/10.1101/716647
https://doi.org/10.1101/716647