Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ulrike Ziebold"'
Autor:
Jane D. Holland, Balázs Györffy, Regina Vogel, Klaus Eckert, Giovanni Valenti, Liang Fang, Philipp Lohneis, Sefer Elezkurtaj, Ulrike Ziebold, Walter Birchmeier
Publikováno v:
Cell Reports, Vol 5, Iss 5, Pp 1214-1227 (2013)
Prognosis for patients with estrogen-receptor (ER)-negative basal breast cancer is poor, and chemotherapy is currently the best therapeutic option. We have generated a compound-mutant mouse model combining the activation of β-catenin and HGF (Wnt-Me
Externí odkaz:
https://doaj.org/article/138326b544464410abf510578ab14508
Autor:
Agnieszka Rybak, Lea H. Gregersen, Markus Landthaler, Antigoni Elefsinioti, Marvin Jens, Sebastian Memczak, Ulrike Ziebold, Mathias Munschauer, Alexander Loewer, Janna Krueger, Christine Kocks, Nikolaus Rajewsky, Francesca Torti, Sebastian D. Mackowiak, Ferdinand le Noble, Luisa Maier
Publikováno v:
Nature. 495:333-338
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circ
Gene expression of pluripotency determinants is conserved between mammalian and planarian stem cells
Autor:
Pinar Önal, Hans-Peter Rahn, Ulrike Ziebold, Catherine Adamidi, Dominic Grün, Guido Mastrobuoni, Stefan Kempa, Yongbo Wang, Agnieszka Rybak, Wei Chen, Jordi Solana, Nikolaus Rajewsky
Publikováno v:
The EMBO Journal. 31:2755-2769
Freshwater planaria possess extreme regeneration capabilities mediated by abundant, pluripotent stem cells (neoblasts) in adult animals. Although planaria emerged as an attractive in vivo model system for stem cell biology, gene expression in neoblas
Autor:
Ulrike Ziebold, Björn von Eyss, Christoph Loddenkemper, Sebastian Memczak, Nikolaus Rajewsky, Katharina Möllmann, Anja Schuetz, Kathrin Muegge, Udo Heinemann, Albrecht Otto, Jonas Maaskola, Mai-Dinh Tanh
Publikováno v:
The EMBO Journal. 31:972-985
The activating E2F-transcription factors are best known for their dependence on the Retinoblastoma protein and their role in cellular proliferation. E2F3 is uniquely amplified in specific human tumours where its expression is inversely correlated wit
Publikováno v:
Seminars in Cell & Developmental Biology. 21:855-863
Canonical Wnt signaling supports the formation and maintenance of stem and cancer stem cells. Recent studies have elucidated epigenetic mechanisms that control pluripotency and stemness, and allow a first assessment how embryonic and tissue stem cell
Autor:
Daniel Pipeleers, Mark Van de Casteele, Marie Chintinne, Gunter Leuckx, Zhidong Ling, Inge Hoebeke, Yves Heremans, Ulrike Ziebold, Ying Cai, Gael Grouwels, Geert Stangé, Harry Heimberg
Publikováno v:
Diabetes
OBJECTIVE Generating functional β-cells by inducing their proliferation may provide new perspectives for cell therapy in diabetes. Transcription factor E2F1 controls G1- to S-phase transition during the cycling of many cell types and is required for
Autor:
Ulrike Ziebold, Nicolas Tapon
Publikováno v:
EMBO reports. 9:1078-1083
The International Conference on Invasion and Metastasis took place between 26 and 29 March 2008, at the Max Delbruck Center for Molecular Medicine in Berlin‐Buch, Germany, and was organized by W. Birchmeier, J. Behrens and U. Ziebold. ![][1] See Gl
Autor:
Ulrike Ziebold, Maximilian Busch, Heike Taubert, Anna La Rosée, Herbert Jäckle, Thomas Häder, Rolando Rivera-Pomar
Publikováno v:
Mechanisms of Development
Drosophila pair-rule gene expression, in an array of seven evenly spaced stripes along the anterior–posterior axis of the blastoderm embryo, is controlled by distinct cis-acting stripe elements. In the anterior region, such elements mediate transcr
Autor:
Ulrike Ziebold, Karl-Heinz Klempnauer
Publikováno v:
Oncogene. 15:1011-1019
A-myb, a conserved member of the Myb proto-oncogene family, encodes a sequence-specific DNA binding protein (A-Myb) that binds to and transactivates promoters containing myb-binding sites. Previous work has suggested that the C-terminus of A-Myb func
Publikováno v:
Current Biology. 7(4):253-260
Background: Cyclins and their catalytic partners, the cyclin-dependent kinases (Cdks), function as key regulators of the eukaryotic cell cycle. Specific cyclin–Cdk complexes are active at successive stages during the cell cycle and control cell-cyc