Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Ulrike Winkler"'
Publikováno v:
JMIR Human Factors, Vol 11, p e45302 (2024)
BackgroundThere are no uniform regulations for the osteopathic profession in Europe. It is subject to country-specific regulations defining who shall be allowed to practice osteopathy and which qualification shall be required. In recent years, legal
Externí odkaz:
https://doaj.org/article/4e9cc497a00c4b23bf6895a4648af451
Autor:
Andrea Trevisiol, Kathrin Kusch, Anna M Steyer, Ingo Gregor, Christos Nardis, Ulrike Winkler, Susanne Köhler, Alejandro Restrepo, Wiebke Möbius, Hauke B Werner, Klaus-Armin Nave, Johannes Hirrlinger
Publikováno v:
PLoS Biology, Vol 18, Iss 11, p e3000943 (2020)
In several neurodegenerative disorders, axonal pathology may originate from impaired oligodendrocyte-to-axon support of energy substrates. We previously established transgenic mice that allow measuring axonal ATP levels in electrically active optic n
Externí odkaz:
https://doaj.org/article/61c88fbc528c462a986b38a93992e117
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Adenosine triphosphate (ATP) is the central energy carrier of all cells and knowledge on the dynamics of the concentration of ATP ([ATP]) provides important insights into the energetic state of a cell. Several genetically encoded fluorescent nanosens
Externí odkaz:
https://doaj.org/article/8ac6b191e45e4a2cbe5531628b7a35d1
Autor:
Johannes Hirrlinger, Grit Marx, Stefanie Besser, Marit Sicker, Susanne Köhler, Petra G. Hirrlinger, Sonja M. Wojcik, Volker Eulenburg, Ulrike Winkler, Swen Hülsmann
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Inhibitory neurons crucially contribute to shaping the breathing rhythm in the brain stem. These neurons use GABA or glycine as neurotransmitter; or co-release GABA and glycine. However, the developmental relationship between GABAergic, glycinergic a
Externí odkaz:
https://doaj.org/article/eacf9a0efb82488e95e9bb06cc3b99f4
Autor:
Dorit Schleinitz, Anna Seidel, Ruth Stassart, Jürgen Klammt, Petra G. Hirrlinger, Ulrike Winkler, Susanne Köhler, John T. Heiker, Ria Schönauer, Joanna Bialek, Knut Krohn, Katrin Hoffmann, Peter Kovacs, Johannes Hirrlinger
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Microcephaly is a devastating condition defined by a small head and small brain compared to the age- and sex-matched population. Mutations in a number of different genes causative for microcephaly have been identified, e.g., MCPH1, WDR62, and ASPM. R
Externí odkaz:
https://doaj.org/article/ca7ee63e04ea4bef90e3730765618b66
Autor:
Andrea Trevisiol, Aiman S Saab, Ulrike Winkler, Grit Marx, Hiromi Imamura, Wiebke Möbius, Kathrin Kusch, Klaus-Armin Nave, Johannes Hirrlinger
Publikováno v:
eLife, Vol 6 (2017)
In several neurodegenerative diseases and myelin disorders, the degeneration profiles of myelinated axons are compatible with underlying energy deficits. However, it is presently impossible to measure selectively axonal ATP levels in the electrically
Externí odkaz:
https://doaj.org/article/5086699597c04e8a86a1cc312f1942f1
Autor:
Stefanie Besser, Marit Sicker, Grit Marx, Ulrike Winkler, Volker Eulenburg, Swen Hülsmann, Johannes Hirrlinger
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129934 (2015)
GABAergic inhibitory neurons are a large population of neurons in the central nervous system (CNS) of mammals and crucially contribute to the function of the circuitry of the brain. To identify specific cell types and investigate their functions labe
Externí odkaz:
https://doaj.org/article/ad3782215ec64d4db8d42789bfc2d5d4
Autor:
Petra G Hirrlinger, Thomas Pannicke, Ulrike Winkler, Thomas Claudepierre, Shweta Varshney, Christine Schulze, Andreas Reichenbach, William J Brunken, Johannes Hirrlinger
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16106 (2011)
Glial cells such as retinal Müller glial cells are involved in potassium ion and water homeostasis of the neural tissue. In these cells, inwardly rectifying potassium (Kir) channels and aquaporin-4 water channels play an important role in the proces
Externí odkaz:
https://doaj.org/article/c748fe01692340e690836adf35eec646
Autor:
Susanna Marg, Ulrike Winkler, Marcello Sestu, Mirko Himmel, Madeleine Schönherr, Janina Bär, Amrit Mann, Markus Moser, Claudia T Mierke, Klemens Rottner, Manfred Blessing, Johannes Hirrlinger, Wolfgang H Ziegler
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11530 (2010)
BackgroundThe cytoskeletal adaptor protein vinculin plays a fundamental role in cell contact regulation and affects central aspects of cell motility, which are essential to both embryonal development and tissue homeostasis. Functional regulation of t
Externí odkaz:
https://doaj.org/article/7e403a87d6c74e40a5011fc9a5b5b55a
Autor:
Johannes Hirrlinger, Robert P Requardt, Ulrike Winkler, Franziska Wilhelm, Christine Schulze, Petra G Hirrlinger
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8354 (2009)
BACKGROUND:DNA recombination technologies such as the Cre/LoxP system advance modern biological research by allowing conditional gene regulation in vivo. However, the precise targeting of a particular cell type at a given time point has remained chal
Externí odkaz:
https://doaj.org/article/4db0cc37e8434fcf906dadea482a7070