Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ulrike Strobel"'
Publikováno v:
Thrombosis Research. 196:400-403
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::987fff6da847f079b258bfb00a6e390f
https://doi.org/10.1016/j.thromres.2020.09.032
https://doi.org/10.1016/j.thromres.2020.09.032
Autor:
Jian Liu, Wen Zhou, Ricarda Raschke, Sven Brandt, Yongmei Xu, Mihaela Delcea, Ulrike Strobel, Martin Mandelkow, Andreas Greinacher, Thi-Huong Nguyen
Publikováno v:
Journal of thrombosis and haemostasis : JTH
Background Heparins are usually produced from animal tissues. It is now possible to synthesize heparins. This provides the abilities to overcome shortages of heparin, to optimize biological effects, and to reduce adverse drug effects. Heparins intera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c894daa85d160479c11ad350f4b6d395
https://doi.org/10.1111/jth.14657
https://doi.org/10.1111/jth.14657
Autor:
Thi-Huong Nguyen, Ricarda Raschke, Jan Wesche, Van-Chien Bui, Mihaela Delcea, Ulrike Strobel, Andreas Greinacher
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 17(7)
Essentials At low pH and low salt concentrations: Maximal conformational change of PF4 upon complexation with heparin occurs. Changing physicochemical conditions may become an approach to better discriminate the signal of platelet-activating- and non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad945935485f8bd3744bd91118bb26a
https://pubmed.ncbi.nlm.nih.gov/31009154
https://pubmed.ncbi.nlm.nih.gov/31009154
Autor:
Volker Kiefel, Tamam Bakchoul, Andreas Greinacher, Jan Wesche, Gregor Jatzlauk, Karina Althaus, Ulrike Strobel, Klaus Muehlenberg
Publikováno v:
Transfusion. 56:67-72
BACKGROUND Drug-induced immune thrombocytopenia (DITP) is an adverse drug reaction associated with platelet (PLT) destruction by drug-dependent antibodies. Demonstration of drug-dependent PLT antibodies is often difficult and can only be rendered by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e241fcc068df14cba7fe7da8d1e9dc9
https://doi.org/10.1111/trf.13284
https://doi.org/10.1111/trf.13284
Autor:
A. Rogolino, Karina Althaus, Rosanna Abbate, Andreas Greinacher, Simon J. Davidson, Tamam Bakchoul, Ulrike Strobel, Gregor Hron
Publikováno v:
Thrombosis Research. 131:e85-e90
Background Heparin-induced thrombocytopenia (HIT) is caused by platelet-activating antibodies that recognize platelet factor 4/heparin (PF4/hep) complexes. The in vitro demonstration of PF4/hep antibodies using functional and immunological methods is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83de6180e8a44c873fd1f9ef2937de6
https://doi.org/10.1016/j.thromres.2013.01.005
https://doi.org/10.1016/j.thromres.2013.01.005
Publikováno v:
Thrombosis Research. 128:256-260
IgG-specific anti-PF4/heparin enzyme-immunoassays (EIAs) are sensitive but not specific for platelet-activating antibodies, the cause of heparin-induced thrombocytopenia (HIT). Two features of EIA reactivity predict for presence of HIT antibodies - t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80f3c2a1e908635741a4c37ea80f531
https://doi.org/10.1016/j.thromres.2011.05.003
https://doi.org/10.1016/j.thromres.2011.05.003
Autor:
Ulrike Strobel, Thomas Kohlmann, Andreas Greinacher, Theodore E. Warkentin, Jo-Ann I. Sheppard
Publikováno v:
Blood. 113:4970-4976
The immune response in heparin-induced thrombocytopenia (HIT) is puzzling: heparin-naive patients can develop IgG antibodies and clinical HIT as early as day 5, and evidence for an anamnestic response on heparin reexposure is lacking. We assessed dai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af071fedc2e2a304e639c930aab15f3
https://doi.org/10.1182/blood-2008-08-173062
https://doi.org/10.1182/blood-2008-08-173062
Autor:
Heyo K. Kroemer, Tetsuya Terasaki, Junichi Kamiie, Juliane Niessen, Gabriele Jedlitschky, Stefan Oswald, Dieter Rosskopf, Hirotaka Kawakami, Sumio Ohtsuki, Katharina Starke, Werner Siegmund, Ulrike Strobel, Markus Grube, Hansjörg Schwertz, Andreas Greinacher, Sandra Bien
Publikováno v:
Drug Metabolism and Disposition. 37:1129-1137
Statins are widely used to treat dyslipidemia. Effects of statins in addition to low-density lipoprotein lowering include altered platelet aggregation, requiring drug uptake into platelets. Possible candidates for mediating intraplatelet accumulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de346e719584cf603f4b9107560674b
https://doi.org/10.1124/dmd.108.024570
https://doi.org/10.1124/dmd.108.024570
Autor:
Gregor, Jatzlauk, Karina, Althaus, Ulrike, Strobel, Volker, Kiefel, Jan, Wesche, Klaus, Muehlenberg, Andreas, Greinacher, Tamam, Bakchoul
Publikováno v:
Transfusion. 56(1)
Drug-induced immune thrombocytopenia (DITP) is an adverse drug reaction associated with platelet (PLT) destruction by drug-dependent antibodies. Demonstration of drug-dependent PLT antibodies is often difficult and can only be rendered by extensive l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c85825a386e36576b71fdd14c1f25cf
https://pubmed.ncbi.nlm.nih.gov/26331798
https://pubmed.ncbi.nlm.nih.gov/26331798
Autor:
Theodore E. Warkentin, Mahmoud A. Omer-Adam, Ulrike Strobel, Werner Weitschies, Georg Papastavrou, Manesh Gopinadhan, Andreas Greinacher, Jens-Uwe Günther, Christiane A. Helm
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 26:2386-2393
Objective— Heparin-induced thrombocytopenia (HIT) is a prothrombotic drug reaction caused by antibodies that recognize positively charged platelet factor 4 (PF4), bound to the polyanion, heparin. The resulting immune complexes activate platelets. U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a88ab77baba0798f5d2dec8f13fe75da
https://doi.org/10.1161/01.atv.0000238350.89477.88
https://doi.org/10.1161/01.atv.0000238350.89477.88