Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Ulrike Schleicher"'
Autor:
Lisa Kohl, Md Nur A Alam Siddique, Barbara Bodendorfer, Raffaela Berger, Annica Preikschat, Christoph Daniel, Martha Ölke, Elisabeth Liebler‐Tenorio, Jan Schulze‐Luehrmann, Michael Mauermeir, Kai‐Ting Yang, Inaya Hayek, Manuela Szperlinski, Jennifer Andrack, Ulrike Schleicher, Aline Bozec, Gerhard Krönke, Peter J Murray, Stefan Wirtz, Masahiro Yamamoto, Valentin Schatz, Jonathan Jantsch, Peter Oefner, Daniel Degrandi, Klaus Pfeffer, Katja Mertens‐Scholz, Simon Rauber, Christian Bogdan, Katja Dettmer, Anja Lührmann, Roland Lang
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 2, Pp n/a-n/a (2023)
Abstract Infection with the intracellular bacterium Coxiella (C.) burnetii can cause chronic Q fever with severe complications and limited treatment options. Here, we identify the enzyme cis‐aconitate decarboxylase 1 (ACOD1 or IRG1) and its product
Externí odkaz:
https://doaj.org/article/1b69987f304e4114b08d5e4633d04bb6
Autor:
Ketema Abdissa, Nanthapon Ruangkiattikul, Wiebke Ahrend, Andreas Nerlich, Andreas Beineke, Kristin Laarmann, Nina Janze, Ulrike Lobermeyer, Abdulhadi Suwandi, Christine Falk, Ulrike Schleicher, Christian Bogdan, Siegfried Weiss, Ralph Goethe
Publikováno v:
Virulence, Vol 11, Iss 1, Pp 465-481 (2020)
Mycobacterium avium subspecies paratuberculosis (MAP) causes Johne’s disease (JD), an incurable chronic intestinal bowel disease in ruminants. JD occurs worldwide and causes enormous economic burden in dairy industry. Research on JD pathobiology is
Externí odkaz:
https://doaj.org/article/195f88f0255048ea8a7eff1678f92304
Autor:
Carolin Sasse, David Barinberg, Stephanie Obermeyer, Andrea Debus, Ulrike Schleicher, Christian Bogdan
Publikováno v:
Pathogens, Vol 11, Iss 8, p 828 (2022)
Interleukin (IL)-4 plays a central role in the initiation of a type 2 T helper cell (Th2) response, which leads to non-healing and progressive infections with the protozoan parasite Leishmania (L.) major. Here, we tested the hypothesis that type 2 in
Externí odkaz:
https://doaj.org/article/90385fb8fa8f4bfebd9fe75517781267
Autor:
Tobias Straub, Marina A. Freudenberg, Ulrike Schleicher, Christian Bogdan, Georg Gasteiger, Hanspeter Pircher
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Exposure to multiple pathogens is common in nature, yet interactions between the immune components targeting bacterial and viral pathogens during co-infection are poorly understood. Here the authors show that bacteria-derived LPS induces cytotoxic NK
Externí odkaz:
https://doaj.org/article/ea8d1ad39a4f4d37855579d39f274857
Autor:
Markus Kindermann, Lisa Knipfer, Stephanie Obermeyer, Uwe Müller, Gottfried Alber, Christian Bogdan, Ulrike Schleicher, Markus F. Neurath, Stefan Wirtz
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Cryptococcus neoformans is an opportunistic fungal pathogen preferentially causing disease in immunocompromised individuals such as organ-transplant-recipients, patients receiving immunosuppressive medications or, in particular, individuals suffering
Externí odkaz:
https://doaj.org/article/89e438a067154663a07bd2d067838e76
Autor:
Natascha Brigo, Christa Pfeifhofer-Obermair, Piotr Tymoszuk, Egon Demetz, Sabine Engl, Marina Barros-Pinkelnig, Stefanie Dichtl, Christine Fischer, Lara Valente De Souza, Verena Petzer, Laura von Raffay, Richard Hilbe, Sylvia Berger, Markus Seifert, Ulrike Schleicher, Christian Bogdan, Günter Weiss
Publikováno v:
Cells, Vol 10, Iss 7, p 1823 (2021)
Arginase 1 (ARG1) is a cytosolic enzyme that cleaves L-arginine, the substrate of inducible nitric oxide synthase (iNOS), and thereby impairs the control of various intracellular pathogens. Herein, we investigated the role of ARG1 during infection wi
Externí odkaz:
https://doaj.org/article/cc2852003617465baa90ac1ff0b2e4c4
Autor:
Eliana Ribechini, James A. Hutchinson, Sabine Hergovits, Marion Heuer, Jörg Lucas, Ulrike Schleicher, Ana-Laura Jordán Garrote, Sarah J. Potter, Paloma Riquelme, Heike Brackmann, Nora Müller, Hartmann Raifer, Ingolf Berberich, Magdalena Huber, Andreas Beilhack, Michael Lohoff, Christian Bogdan, Matthias Eyrich, Heike M. Hermanns, Edward K. Geissler, Manfred B. Lutz
Publikováno v:
Blood Advances, Vol 1, Iss 14, Pp 947-960 (2017)
Abstract: Granulocyte-macrophage colony-stimulating factor (GM-CSF) controls proliferation and survival of myeloid cells including monocytes. Here, we describe a time-dependent licensing process driven by GM-CSF in murine Ly6Chigh and human CD14+ mon
Externí odkaz:
https://doaj.org/article/01939da1159e4606bd40390d8e10d0d3
Autor:
Ketema Abdissa, Andreas Nerlich, Andreas Beineke, Nanthapon Ruangkiattikul, Vinay Pawar, Ulrike Heise, Nina Janze, Christine Falk, Dunja Bruder, Ulrike Schleicher, Christian Bogdan, Siegfried Weiss, Ralph Goethe
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Myeloid-derived suppressor cells (MDSC) are immature myeloid cells with immunomodulatory function. To study the mechanism by which MDSC affect antimicrobial immunity, we infected mice with two M. avium strains of differential virulence, highly virule
Externí odkaz:
https://doaj.org/article/7fc6cfa80e9443f985c5e473de8e5ae6
Autor:
Francisca F. Almeida, Sara Tognarelli, Antoine Marçais, Andrew J. Kueh, Miriam E. Friede, Yang Liao, Simon N. Willis, Kylie Luong, Fabrice Faure, Francois E. Mercier, Justine Galluso, Matthew Firth, Emilie Narni-Mancinelli, Bushra Rais, David T. Scadden, Francesco Spallotta, Sandra Weil, Ariane Giannattasio, Franziska Kalensee, Tobias Zöller, Nicholas D. Huntington, Ulrike Schleicher, Andreas G. Chiocchetti, Sophie Ugolini, Marco J. Herold, Wei Shi, Joachim Koch, Alexander Steinle, Eric Vivier, Thierry Walzer, Gabrielle T. Belz, Evelyn Ullrich
Publikováno v:
OncoImmunology, Vol 7, Iss 10 (2018)
NKp46 (CD335) is a surface receptor shared by both human and mouse natural killer (NK) cells and innate lymphoid cells (ILCs) that transduces activating signals necessary to eliminate virus-infected cells and tumors. Here, we describe a spontaneous p
Externí odkaz:
https://doaj.org/article/8e7af400c12d41358fe2c4876853dbc4
Autor:
Ulrike Schleicher, Katrin Paduch, Andrea Debus, Stephanie Obermeyer, Till König, Jessica C. Kling, Eliana Ribechini, Diana Dudziak, Dimitrios Mougiakakos, Peter J. Murray, Renato Ostuni, Heinrich Körner, Christian Bogdan
Publikováno v:
Cell Reports, Vol 15, Iss 5, Pp 1062-1075 (2016)
Neutralization or deletion of tumor necrosis factor (TNF) causes loss of control of intracellular pathogens in mice and humans, but the underlying mechanisms are incompletely understood. Here, we found that TNF antagonized alternative activation of m
Externí odkaz:
https://doaj.org/article/6fad66d1b5b74e94a18ab67af0adf4d1