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Autor:
Walter Jeske, Bhavna S Gaikwad, Debra Hoppensteadt, Peter Bacher, Sarfraz Ahmad, Jawed Fareed, Jeanine M. Walenga, N. Bender, Sylvia Haas, Frank Misselwitz, Helen Lietz, Harry L. Messmore, Ulrike Reid
Publikováno v:
Thrombosis research. 108(1)
The pathophysiology of heparin-induced thrombocytopenia (HIT) syndrome is mediated via a heterogeneous group of heparin(s)-platelet factor 4 (H-PF4) complexes bound to their antibodies. These anti-H-PF4 (AHPF4) antibodies that are capable of binding