SIFamide Translates Hunger Signals into Appetitive and Feeding Behavior in Drosophila

Autor: Carlotta Martelli, Ulrike Pech, Simon Kobbenbring, Dennis Pauls, Britta Bahl, Mirjam Vanessa Sommer, Atefeh Pooryasin, Jonas Barth, Carmina Warth Perez Arias, Chrystalleni Vassiliou, Abud Jose Farca Luna, Haiko Poppinga, Florian Gerhard Richter, Christian Wegener, André Fiala, Thomas Riemensperger

Publikováno v: Cell Reports, Vol 20, Iss 2, Pp 464-478 (2017)

Animal behavior is, on the one hand, controlled by neuronal circuits that integrate external sensory stimuli and induce appropriate motor responses. On the other hand, stimulus-evoked or internally generated behavior can be influenced by motivational

Externí odkaz: https://doaj.org/article/1e9e77379a6b42cb88dfd265cec21c54

A Single Dopamine Pathway Underlies Progressive Locomotor Deficits in a Drosophila Model of Parkinson Disease

Autor: Thomas Riemensperger, Abdul-Raouf Issa, Ulrike Pech, Hélène Coulom, Mỹ-Vân Nguyễn, Marlène Cassar, Mélanie Jacquet, André Fiala, Serge Birman

Publikováno v: Cell Reports, Vol 5, Iss 4, Pp 952-960 (2013)

Expression of the human Parkinson-disease-associated protein α-synuclein in all Drosophila neurons induces progressive locomotor deficits. Here, we identify a group of 15 dopaminergic neurons per hemisphere in the anterior medial region of the brain

Externí odkaz: https://doaj.org/article/c810518659ba41b7a4a7b748d12bc7b6

Aralar Sequesters GABA into Hyperactive Mitochondria, Causing Social Behavior Deficits

Autor: André Fiala, Brett S. Abrahams, J. Douglas Armstrong, August B. Smit, Colin Mclean, Young Jae Woo, Claudia Bagni, Angela Giangrande, Tilmann Achsel, Marco Spinazzi, Ka Wan Li, Ulrike Pech, Patrick Callaerts, Alexandros K. Kanellopoulos, Vittoria Mariano

Publikováno v: Kanellopoulos, A K, Mariano, V, Spinazzi, M, Woo, Y J, McLean, C, Pech, U, Li, K W, Armstrong, J D, Giangrande, A, Callaerts, P, Smit, A B, Abrahams, B S, Fiala, A, Achsel, T & Bagni, C 2020, ' Aralar Sequesters GABA into Hyperactive Mitochondria, Causing Social Behavior Deficits ', Cell, vol. 180, no. 6, e20, pp. 1178-1197 . https://doi.org/10.1016/j.cell.2020.02.044
Cell
Cell, Elsevier, 2020, 180 (6), pp.1178-1197.e20. ⟨10.1016/j.cell.2020.02.044⟩
Cell, 180(6), 1178-1197.e20. Cell Press
Kanellopoulos, A K, Mariano, V, Spinazzi, M, Woo, Y J, McLean, C, Pech, U, Li, K W, Armstrong, J D, Giangrande, A, Callaerts, P, Smit, A B, Abrahams, B S, Fiala, A, Achsel, T & Bagni, C 2020, ' Aralar Sequesters GABA into Hyperactive Mitochondria, Causing Social Behavior Deficits ', Cell, vol. 180, no. 6, pp. 1178-1197.e20 . https://doi.org/10.1016/j.cell.2020.02.044
Cell 180(6), 1178-1197.e20 (2020). doi:10.1016/j.cell.2020.02.044
Signal Transduction and Targeted Therapy

Social impairment is frequently associated with mitochondrial dysfunction and altered neurotransmission. Although mitochondrial function is crucial for brain homeostasis, it remains unknown whether mitochondrial disruption contributes to social behav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c7fe07f583c42e40b1ba624b773e56
https://hdl.handle.net/20.500.11820/24a7c2ca-e248-42f0-814f-2b1af9b8d1e4

SIFamide Translates Hunger Signals into Appetitive and Feeding Behavior in Drosophila

Autor: Dennis Pauls, Carmina Warth Perez Arias, André Fiala, Jonas Barth, Christian Wegener, Atefeh Pooryasin, Abud J. Farca Luna, Carlotta Martelli, Britta Bahl, Haiko Poppinga, Ulrike Pech, Simon Kobbenbring, Thomas Riemensperger, Florian Gerhard Richter, Chrystalleni Vassiliou, Mirjam Vanessa Sommer

Publikováno v: Cell Reports, Vol 20, Iss 2, Pp 464-478 (2017)

Animal behavior is, on the one hand, controlled by neuronal circuits that integrate external sensory stimuli and induce appropriate motor responses. On the other hand, stimulus-evoked or internally generated behavior can be influenced by motivational

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf333667c2d89995d339acbc9dcd6be
https://doi.org/10.1016/j.celrep.2017.06.043

Spermidine Suppresses Age-Associated Memory Impairment by Preventing Adverse Increase of Presynaptic Active Zone Size and Release

Autor: Till F. M. Andlauer, Frank Madeo, Joern Dengjel, Stephan J. Sigrist, Ulrike Pech, Varun K Gupta, Marta Maglione, Martin Schwärzel, Christine B. Beuschel, Anuradha Bhukel, André Fiala, Anatoli Ender, Kerstin Thriene, Andreas Fulterer, Thorsten Mielke, René Bushow, Christine Quentin, Stephan F. Mauermann, Emmanuel Antwi-Adjei

Publikováno v: PLOS BIOLOGY
PLoS Biology, Vol 14, Iss 9, p e1002563 (2016)
PLoS Biology

Memories are assumed to be formed by sets of synapses changing their structural or functional performance. The efficacy of forming new memories declines with advancing age, but the synaptic changes underlying age-induced memory impairment remain poor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45ee7add12e765405b83747828353ea
https://hdl.handle.net/11858/00-001M-0000-002C-5E6F-C11858/00-001M-0000-002C-5EED-1